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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MMRN1
Full Name:
Multimerin-1
Alias:
ECM; Elastin microfibril interface located 4; Elastin microfibril interface located protein 4; Elastin microfibril interfacer 4; EMILIN4; EMILIN-4; Endothelial cell multimerin; Endothelial cell multimerin 1; Glycoprotein Ia*; GPIa*; MMRN; Multimerin 1; Multimerin-1
Type:
Mass (Da):
138092
Number AA:
1228
UniProt ID:
Q13201
International Prot ID:
IPI00012269
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
GO:0031093
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0007596
GO:0007155
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
G
G
I
G
L
N
N
S
K
H
S
W
T
I
P
Site 2
S35
T
I
P
E
D
G
N
S
Q
K
T
M
P
S
A
Site 3
T38
E
D
G
N
S
Q
K
T
M
P
S
A
S
V
P
Site 4
S41
N
S
Q
K
T
M
P
S
A
S
V
P
P
N
K
Site 5
S43
Q
K
T
M
P
S
A
S
V
P
P
N
K
I
Q
Site 6
S51
V
P
P
N
K
I
Q
S
L
Q
I
L
P
T
T
Site 7
T57
Q
S
L
Q
I
L
P
T
T
R
V
M
S
A
E
Site 8
T68
M
S
A
E
I
A
T
T
P
E
A
R
T
S
E
Site 9
S74
T
T
P
E
A
R
T
S
E
D
S
L
L
K
S
Site 10
S77
E
A
R
T
S
E
D
S
L
L
K
S
T
L
P
Site 11
S81
S
E
D
S
L
L
K
S
T
L
P
P
S
E
T
Site 12
T82
E
D
S
L
L
K
S
T
L
P
P
S
E
T
S
Site 13
S86
L
K
S
T
L
P
P
S
E
T
S
A
P
A
E
Site 14
T88
S
T
L
P
P
S
E
T
S
A
P
A
E
G
V
Site 15
T99
A
E
G
V
R
N
Q
T
L
T
S
T
E
K
A
Site 16
T101
G
V
R
N
Q
T
L
T
S
T
E
K
A
E
G
Site 17
S131
K
F
N
P
G
A
E
S
V
V
L
S
N
S
T
Site 18
S144
S
T
L
K
F
L
Q
S
F
A
R
K
S
N
E
Site 19
S149
L
Q
S
F
A
R
K
S
N
E
Q
A
T
S
L
Site 20
S155
K
S
N
E
Q
A
T
S
L
N
T
V
G
G
T
Site 21
T158
E
Q
A
T
S
L
N
T
V
G
G
T
G
G
I
Site 22
T182
G
N
R
A
P
R
E
T
Y
L
S
R
G
D
S
Site 23
Y183
N
R
A
P
R
E
T
Y
L
S
R
G
D
S
S
Site 24
S185
A
P
R
E
T
Y
L
S
R
G
D
S
S
S
S
Site 25
S189
T
Y
L
S
R
G
D
S
S
S
S
Q
R
T
D
Site 26
S191
L
S
R
G
D
S
S
S
S
Q
R
T
D
Y
Q
Site 27
S192
S
R
G
D
S
S
S
S
Q
R
T
D
Y
Q
K
Site 28
T195
D
S
S
S
S
Q
R
T
D
Y
Q
K
S
N
F
Site 29
Y197
S
S
S
Q
R
T
D
Y
Q
K
S
N
F
E
T
Site 30
S200
Q
R
T
D
Y
Q
K
S
N
F
E
T
T
R
G
Site 31
Y213
R
G
K
N
W
C
A
Y
V
H
T
R
L
S
P
Site 32
Y230
I
L
D
N
Q
V
T
Y
V
P
G
G
K
G
P
Site 33
S249
G
G
S
C
P
Q
R
S
Q
K
I
S
N
P
V
Site 34
S253
P
Q
R
S
Q
K
I
S
N
P
V
Y
R
M
Q
Site 35
Y257
Q
K
I
S
N
P
V
Y
R
M
Q
H
K
I
V
Site 36
Y275
D
W
R
C
C
P
G
Y
S
G
P
K
C
Q
L
Site 37
S289
L
R
A
Q
E
Q
Q
S
L
I
H
T
N
Q
A
Site 38
T293
E
Q
Q
S
L
I
H
T
N
Q
A
E
S
H
T
Site 39
Y330
K
M
T
D
Q
V
N
Y
Q
A
M
K
L
T
L
Site 40
S346
Q
K
K
I
D
N
I
S
L
T
V
N
D
V
R
Site 41
T348
K
I
D
N
I
S
L
T
V
N
D
V
R
N
T
Site 42
T355
T
V
N
D
V
R
N
T
Y
S
S
L
E
G
K
Site 43
Y356
V
N
D
V
R
N
T
Y
S
S
L
E
G
K
V
Site 44
S358
D
V
R
N
T
Y
S
S
L
E
G
K
V
S
E
Site 45
S364
S
S
L
E
G
K
V
S
E
D
K
S
R
E
F
Site 46
S368
G
K
V
S
E
D
K
S
R
E
F
Q
S
L
L
Site 47
S373
D
K
S
R
E
F
Q
S
L
L
K
G
L
K
S
Site 48
S382
L
K
G
L
K
S
K
S
I
N
V
L
I
R
D
Site 49
T412
T
V
A
Q
L
F
K
T
V
S
S
L
S
E
D
Site 50
S414
A
Q
L
F
K
T
V
S
S
L
S
E
D
L
E
Site 51
S415
Q
L
F
K
T
V
S
S
L
S
E
D
L
E
S
Site 52
S417
F
K
T
V
S
S
L
S
E
D
L
E
S
T
R
Site 53
S422
S
L
S
E
D
L
E
S
T
R
Q
I
I
Q
K
Site 54
T452
L
V
Q
E
N
R
P
T
L
T
D
I
V
E
L
Site 55
T473
V
R
Q
E
M
T
L
T
C
E
K
P
I
K
E
Site 56
T486
K
E
L
E
V
K
Q
T
H
L
E
G
A
L
E
Site 57
S497
G
A
L
E
Q
E
H
S
R
S
I
L
Y
Y
E
Site 58
S499
L
E
Q
E
H
S
R
S
I
L
Y
Y
E
S
L
Site 59
Y502
E
H
S
R
S
I
L
Y
Y
E
S
L
N
K
T
Site 60
Y503
H
S
R
S
I
L
Y
Y
E
S
L
N
K
T
L
Site 61
S505
R
S
I
L
Y
Y
E
S
L
N
K
T
L
S
K
Site 62
T509
Y
Y
E
S
L
N
K
T
L
S
K
L
K
E
V
Site 63
S511
E
S
L
N
K
T
L
S
K
L
K
E
V
H
E
Site 64
S522
E
V
H
E
Q
L
L
S
T
E
Q
V
S
D
Q
Site 65
T523
V
H
E
Q
L
L
S
T
E
Q
V
S
D
Q
K
Site 66
T543
E
S
V
S
N
N
V
T
E
Y
M
S
T
L
H
Site 67
Y545
V
S
N
N
V
T
E
Y
M
S
T
L
H
E
N
Site 68
T548
N
V
T
E
Y
M
S
T
L
H
E
N
I
K
K
Site 69
S572
E
D
L
H
I
Q
E
S
K
I
N
N
L
T
V
Site 70
T578
E
S
K
I
N
N
L
T
V
S
L
E
M
E
K
Site 71
S580
K
I
N
N
L
T
V
S
L
E
M
E
K
E
S
Site 72
S587
S
L
E
M
E
K
E
S
L
R
G
E
C
E
D
Site 73
T610
F
K
F
Q
L
K
D
T
E
E
N
L
H
V
L
Site 74
T643
S
E
Q
L
N
D
L
T
Y
D
M
E
I
L
Q
Site 75
Y644
E
Q
L
N
D
L
T
Y
D
M
E
I
L
Q
P
Site 76
S658
P
L
L
E
Q
G
A
S
L
R
Q
T
M
T
Y
Site 77
T662
Q
G
A
S
L
R
Q
T
M
T
Y
E
Q
P
K
Site 78
Y665
S
L
R
Q
T
M
T
Y
E
Q
P
K
E
A
I
Site 79
T682
R
K
K
I
E
N
L
T
S
A
V
N
S
L
N
Site 80
S683
K
K
I
E
N
L
T
S
A
V
N
S
L
N
F
Site 81
T696
N
F
I
I
K
E
L
T
K
R
H
N
L
L
R
Site 82
Y720
L
E
R
R
I
N
E
Y
A
L
E
M
E
D
G
Site 83
T733
D
G
L
N
K
T
M
T
I
I
N
N
A
I
D
Site 84
Y746
I
D
F
I
Q
D
N
Y
A
L
K
E
T
L
S
Site 85
T754
A
L
K
E
T
L
S
T
I
K
D
N
S
E
I
Site 86
T771
K
C
T
S
D
M
E
T
I
L
T
F
I
P
Q
Site 87
T774
S
D
M
E
T
I
L
T
F
I
P
Q
F
H
R
Site 88
S785
Q
F
H
R
L
N
D
S
I
Q
T
L
V
N
D
Site 89
Y796
L
V
N
D
N
Q
R
Y
N
F
V
L
Q
V
A
Site 90
Y837
T
T
S
Q
V
R
K
Y
Q
Q
N
M
S
H
L
Site 91
S842
R
K
Y
Q
Q
N
M
S
H
L
E
E
K
L
L
Site 92
T851
L
E
E
K
L
L
L
T
T
K
I
S
K
N
F
Site 93
T860
K
I
S
K
N
F
E
T
R
L
Q
D
I
E
S
Site 94
S867
T
R
L
Q
D
I
E
S
K
V
T
Q
T
L
I
Site 95
T870
Q
D
I
E
S
K
V
T
Q
T
L
I
P
Y
Y
Site 96
Y877
T
Q
T
L
I
P
Y
Y
I
S
V
K
K
G
S
Site 97
S901
L
Q
L
Q
V
L
N
S
R
F
K
A
L
E
A
Site 98
S919
H
L
S
I
N
F
F
S
L
N
K
T
L
H
E
Site 99
T929
K
T
L
H
E
V
L
T
M
C
H
N
A
S
T
Site 100
S935
L
T
M
C
H
N
A
S
T
S
V
S
E
L
N
Site 101
S937
M
C
H
N
A
S
T
S
V
S
E
L
N
A
T
Site 102
S939
H
N
A
S
T
S
V
S
E
L
N
A
T
I
P
Site 103
T944
S
V
S
E
L
N
A
T
I
P
K
W
I
K
H
Site 104
S993
I
D
R
S
L
P
G
S
L
A
N
V
V
K
S
Site 105
S1000
S
L
A
N
V
V
K
S
Q
K
Q
V
K
S
L
Site 106
S1006
K
S
Q
K
Q
V
K
S
L
P
K
K
I
N
A
Site 107
T1023
K
P
T
V
N
L
T
T
V
L
I
G
R
T
Q
Site 108
T1033
I
G
R
T
Q
R
N
T
D
N
I
I
Y
P
E
Site 109
Y1038
R
N
T
D
N
I
I
Y
P
E
E
Y
S
S
C
Site 110
Y1042
N
I
I
Y
P
E
E
Y
S
S
C
S
R
H
P
Site 111
S1046
P
E
E
Y
S
S
C
S
R
H
P
C
Q
N
G
Site 112
S1091
N
A
L
A
P
D
F
S
K
G
S
Y
R
Y
A
Site 113
S1094
A
P
D
F
S
K
G
S
Y
R
Y
A
P
M
V
Site 114
Y1095
P
D
F
S
K
G
S
Y
R
Y
A
P
M
V
A
Site 115
Y1126
F
N
N
L
D
V
N
Y
G
A
S
Y
T
P
R
Site 116
S1129
L
D
V
N
Y
G
A
S
Y
T
P
R
T
G
K
Site 117
Y1130
D
V
N
Y
G
A
S
Y
T
P
R
T
G
K
F
Site 118
T1131
V
N
Y
G
A
S
Y
T
P
R
T
G
K
F
R
Site 119
T1209
W
L
R
L
A
K
G
T
I
P
A
K
F
P
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation