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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLA
Full Name:
Src-like-adapter
Alias:
SLA1; SLAP; SLAP1; Src-like-adaptor
Type:
Adaptor/scaffold
Mass (Da):
31156
Number AA:
276
UniProt ID:
Q13239
International Prot ID:
IPI00009499
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005768
Uniprot
OncoNet
Molecular Function:
GO:0005070
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
G
N
S
M
K
S
T
P
A
P
A
E
R
Site 2
T8
M
G
N
S
M
K
S
T
P
A
P
A
E
R
P
Site 3
S24
P
N
P
E
G
L
D
S
D
F
L
A
V
L
S
Site 4
S35
A
V
L
S
D
Y
P
S
P
D
I
S
P
P
I
Site 5
S39
D
Y
P
S
P
D
I
S
P
P
I
F
R
R
G
Site 6
S53
G
E
K
L
R
V
I
S
D
E
G
G
W
W
K
Site 7
S63
G
G
W
W
K
A
I
S
L
S
T
G
R
E
S
Site 8
S65
W
W
K
A
I
S
L
S
T
G
R
E
S
Y
I
Site 9
T66
W
K
A
I
S
L
S
T
G
R
E
S
Y
I
P
Site 10
S107
L
P
D
T
K
V
G
S
F
M
I
R
E
S
E
Site 11
S113
G
S
F
M
I
R
E
S
E
T
K
K
G
F
Y
Site 12
S121
E
T
K
K
G
F
Y
S
L
S
V
R
H
R
Q
Site 13
S123
K
K
G
F
Y
S
L
S
V
R
H
R
Q
V
K
Site 14
Y132
R
H
R
Q
V
K
H
Y
R
I
F
R
L
P
N
Site 15
Y143
R
L
P
N
N
W
Y
Y
I
S
P
R
L
T
F
Site 16
T149
Y
Y
I
S
P
R
L
T
F
Q
C
L
E
D
L
Site 17
S161
E
D
L
V
N
H
Y
S
E
V
A
D
G
L
C
Site 18
S179
T
T
P
C
L
T
Q
S
T
A
A
P
A
V
R
Site 19
S189
P
A
V
R
A
S
S
S
P
V
T
L
R
Q
K
Site 20
S190
P
A
V
R
A
S
S
S
P
V
T
L
R
Q
K
Site 21
T193
R
A
S
S
S
P
V
T
L
R
Q
K
T
V
D
Site 22
T198
P
V
T
L
R
Q
K
T
V
D
W
R
R
V
S
Site 23
S205
T
V
D
W
R
R
V
S
R
L
Q
E
D
P
E
Site 24
T214
L
Q
E
D
P
E
G
T
E
N
P
L
G
V
D
Site 25
S223
N
P
L
G
V
D
E
S
L
F
S
Y
G
L
R
Site 26
S226
G
V
D
E
S
L
F
S
Y
G
L
R
E
S
I
Site 27
Y227
V
D
E
S
L
F
S
Y
G
L
R
E
S
I
A
Site 28
S235
G
L
R
E
S
I
A
S
Y
L
S
L
T
S
E
Site 29
Y236
L
R
E
S
I
A
S
Y
L
S
L
T
S
E
D
Site 30
S238
E
S
I
A
S
Y
L
S
L
T
S
E
D
N
T
Site 31
S241
A
S
Y
L
S
L
T
S
E
D
N
T
S
F
D
Site 32
T245
S
L
T
S
E
D
N
T
S
F
D
R
K
K
K
Site 33
S246
L
T
S
E
D
N
T
S
F
D
R
K
K
K
S
Site 34
S253
S
F
D
R
K
K
K
S
I
S
L
M
Y
G
G
Site 35
S255
D
R
K
K
K
S
I
S
L
M
Y
G
G
S
K
Site 36
Y258
K
K
S
I
S
L
M
Y
G
G
S
K
R
K
S
Site 37
S261
I
S
L
M
Y
G
G
S
K
R
K
S
S
F
F
Site 38
S265
Y
G
G
S
K
R
K
S
S
F
F
S
S
P
P
Site 39
S266
G
G
S
K
R
K
S
S
F
F
S
S
P
P
Y
Site 40
S269
K
R
K
S
S
F
F
S
S
P
P
Y
F
E
D
Site 41
S270
R
K
S
S
F
F
S
S
P
P
Y
F
E
D
_
Site 42
Y273
S
F
F
S
S
P
P
Y
F
E
D
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation