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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SFRS5
Full Name:
Serine/arginine-rich splicing factor 5
Alias:
Delayed-early protein HRS; HRS; Pre-mRNA splicing factor SRP40; Pre-mRNA-splicing factor SRP40; SFR5; SRP40
Type:
RNA processing; RNA binding protein
Mass (Da):
31264
Number AA:
272
UniProt ID:
Q13243
International Prot ID:
IPI00012341
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0000166
PhosphoSite+
KinaseNET
Biological Process:
GO:0006376
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y27
V
E
R
F
F
K
G
Y
G
R
I
R
D
I
D
Site 2
Y55
R
D
A
D
D
A
V
Y
E
L
D
G
K
E
L
Site 3
S64
L
D
G
K
E
L
C
S
E
R
V
T
I
E
H
Site 4
T68
E
L
C
S
E
R
V
T
I
E
H
A
R
A
R
Site 5
S76
I
E
H
A
R
A
R
S
R
G
G
R
G
R
G
Site 6
Y85
G
G
R
G
R
G
R
Y
S
D
R
F
S
S
R
Site 7
S86
G
R
G
R
G
R
Y
S
D
R
F
S
S
R
R
Site 8
S90
G
R
Y
S
D
R
F
S
S
R
R
P
R
N
D
Site 9
S91
R
Y
S
D
R
F
S
S
R
R
P
R
N
D
R
Site 10
S116
R
L
I
V
E
N
L
S
S
R
V
S
W
Q
D
Site 11
S117
L
I
V
E
N
L
S
S
R
V
S
W
Q
D
L
Site 12
S120
E
N
L
S
S
R
V
S
W
Q
D
L
K
D
F
Site 13
T135
M
R
Q
A
G
E
V
T
F
A
D
A
H
R
P
Site 14
S153
E
G
V
V
E
F
A
S
Y
G
D
L
K
N
A
Site 15
S180
K
I
K
L
I
E
G
S
K
R
H
S
R
S
R
Site 16
S184
I
E
G
S
K
R
H
S
R
S
R
S
R
S
R
Site 17
S186
G
S
K
R
H
S
R
S
R
S
R
S
R
S
R
Site 18
S188
K
R
H
S
R
S
R
S
R
S
R
S
R
T
R
Site 19
S190
H
S
R
S
R
S
R
S
R
S
R
T
R
S
S
Site 20
S192
R
S
R
S
R
S
R
S
R
T
R
S
S
S
R
Site 21
T194
R
S
R
S
R
S
R
T
R
S
S
S
R
S
R
Site 22
S196
R
S
R
S
R
T
R
S
S
S
R
S
R
S
R
Site 23
S197
S
R
S
R
T
R
S
S
S
R
S
R
S
R
S
Site 24
S198
R
S
R
T
R
S
S
S
R
S
R
S
R
S
R
Site 25
S200
R
T
R
S
S
S
R
S
R
S
R
S
R
S
R
Site 26
S202
R
S
S
S
R
S
R
S
R
S
R
S
R
S
R
Site 27
S204
S
S
R
S
R
S
R
S
R
S
R
S
R
K
S
Site 28
S206
R
S
R
S
R
S
R
S
R
S
R
K
S
Y
S
Site 29
S208
R
S
R
S
R
S
R
S
R
K
S
Y
S
R
S
Site 30
S211
S
R
S
R
S
R
K
S
Y
S
R
S
R
S
R
Site 31
Y212
R
S
R
S
R
K
S
Y
S
R
S
R
S
R
S
Site 32
S213
S
R
S
R
K
S
Y
S
R
S
R
S
R
S
R
Site 33
S215
S
R
K
S
Y
S
R
S
R
S
R
S
R
S
R
Site 34
S217
K
S
Y
S
R
S
R
S
R
S
R
S
R
S
R
Site 35
S219
Y
S
R
S
R
S
R
S
R
S
R
S
R
S
K
Site 36
S221
R
S
R
S
R
S
R
S
R
S
R
S
K
S
R
Site 37
S223
R
S
R
S
R
S
R
S
R
S
K
S
R
S
V
Site 38
S225
R
S
R
S
R
S
R
S
K
S
R
S
V
S
R
Site 39
S227
R
S
R
S
R
S
K
S
R
S
V
S
R
S
P
Site 40
S229
R
S
R
S
K
S
R
S
V
S
R
S
P
V
P
Site 41
S231
R
S
K
S
R
S
V
S
R
S
P
V
P
E
K
Site 42
S233
K
S
R
S
V
S
R
S
P
V
P
E
K
S
Q
Site 43
S239
R
S
P
V
P
E
K
S
Q
K
R
G
S
S
S
Site 44
S244
E
K
S
Q
K
R
G
S
S
S
R
S
K
S
P
Site 45
S245
K
S
Q
K
R
G
S
S
S
R
S
K
S
P
A
Site 46
S246
S
Q
K
R
G
S
S
S
R
S
K
S
P
A
S
Site 47
S248
K
R
G
S
S
S
R
S
K
S
P
A
S
V
D
Site 48
S250
G
S
S
S
R
S
K
S
P
A
S
V
D
R
Q
Site 49
S253
S
R
S
K
S
P
A
S
V
D
R
Q
R
S
R
Site 50
S259
A
S
V
D
R
Q
R
S
R
S
R
S
R
S
R
Site 51
S261
V
D
R
Q
R
S
R
S
R
S
R
S
R
S
V
Site 52
S263
R
Q
R
S
R
S
R
S
R
S
R
S
V
D
S
Site 53
S265
R
S
R
S
R
S
R
S
R
S
V
D
S
G
N
Site 54
S267
R
S
R
S
R
S
R
S
V
D
S
G
N
_
_
Site 55
S270
S
R
S
R
S
V
D
S
G
N
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation