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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EIF3I
Full Name:
Eukaryotic translation initiation factor 3 subunit I
Alias:
EIF-3 beta; EIF3 p36; EIF3-beta; EIF3i; EIF3-p36; EIF3S2; Eukaryotic translation initiation factor 3 subunit 2; Eukaryotic translation initiation factor 3, subunit I; IF32; TGF-beta receptor interacting protein 1; TRIP1; TRIP-1
Type:
Translation
Mass (Da):
36502
Number AA:
325
UniProt ID:
Q13347
International Prot ID:
IPI00012795
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005852
GO:0032991
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003743
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006412
GO:0006417
GO:0006446
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
L
L
Q
G
H
E
R
S
I
T
Q
I
K
Y
N
Site 2
T14
Q
G
H
E
R
S
I
T
Q
I
K
Y
N
R
E
Site 3
Y18
R
S
I
T
Q
I
K
Y
N
R
E
G
D
L
L
Site 4
Y38
D
P
I
V
N
V
W
Y
S
V
N
G
E
R
L
Site 5
S39
P
I
V
N
V
W
Y
S
V
N
G
E
R
L
G
Site 6
T47
V
N
G
E
R
L
G
T
Y
M
G
H
T
G
A
Site 7
Y48
N
G
E
R
L
G
T
Y
M
G
H
T
G
A
V
Site 8
S71
T
K
H
V
L
T
G
S
A
D
N
S
C
R
L
Site 9
T92
K
Q
L
A
L
L
K
T
N
S
A
V
R
T
C
Site 10
T98
K
T
N
S
A
V
R
T
C
G
F
D
F
G
G
Site 11
Y118
S
T
D
K
Q
M
G
Y
Q
C
F
V
S
F
F
Site 12
S131
F
F
D
L
R
D
P
S
Q
I
D
N
N
E
P
Site 13
Y139
Q
I
D
N
N
E
P
Y
M
K
I
P
C
N
D
Site 14
S151
C
N
D
S
K
I
T
S
A
V
W
G
P
L
G
Site 15
Y173
E
S
G
E
L
N
Q
Y
S
A
K
S
G
E
V
Site 16
S174
S
G
E
L
N
Q
Y
S
A
K
S
G
E
V
L
Site 17
S177
L
N
Q
Y
S
A
K
S
G
E
V
L
V
N
V
Site 18
S207
M
T
M
F
V
T
A
S
K
D
N
T
A
K
L
Site 19
T211
V
T
A
S
K
D
N
T
A
K
L
F
D
S
T
Site 20
S217
N
T
A
K
L
F
D
S
T
T
L
E
H
Q
K
Site 21
T218
T
A
K
L
F
D
S
T
T
L
E
H
Q
K
T
Site 22
T219
A
K
L
F
D
S
T
T
L
E
H
Q
K
T
F
Site 23
T225
T
T
L
E
H
Q
K
T
F
R
T
E
R
P
V
Site 24
T228
E
H
Q
K
T
F
R
T
E
R
P
V
N
S
A
Site 25
S234
R
T
E
R
P
V
N
S
A
A
L
S
P
N
Y
Site 26
S238
P
V
N
S
A
A
L
S
P
N
Y
D
H
V
V
Site 27
Y241
S
A
A
L
S
P
N
Y
D
H
V
V
L
G
G
Site 28
T256
G
Q
E
A
M
D
V
T
T
T
S
T
R
I
G
Site 29
S259
A
M
D
V
T
T
T
S
T
R
I
G
K
F
E
Site 30
S290
G
H
F
G
P
I
N
S
V
A
F
H
P
D
G
Site 31
S299
A
F
H
P
D
G
K
S
Y
S
S
G
G
E
D
Site 32
Y300
F
H
P
D
G
K
S
Y
S
S
G
G
E
D
G
Site 33
S301
H
P
D
G
K
S
Y
S
S
G
G
E
D
G
Y
Site 34
Y308
S
S
G
G
E
D
G
Y
V
R
I
H
Y
F
D
Site 35
Y313
D
G
Y
V
R
I
H
Y
F
D
P
Q
Y
F
E
Site 36
Y318
I
H
Y
F
D
P
Q
Y
F
E
F
E
F
E
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation