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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KLF1
Full Name:
Krueppel-like factor 1
Alias:
EKLF; Erythroid krueppel-like transcription factor; Erythroid Kruppel-like factor; Erythroid transcription factor; Kruppel-like factor 1 (erythroid)
Type:
Transcription factor
Mass (Da):
38202
Number AA:
362
UniProt ID:
Q13351
International Prot ID:
IPI00012816
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003700
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
L
P
S
I
S
T
L
T
A
L
G
P
F
P
D
Site 2
T23
A
L
G
P
F
P
D
T
Q
D
D
F
L
K
W
Site 3
T47
G
P
G
P
P
D
P
T
E
P
P
L
H
V
K
Site 4
S55
E
P
P
L
H
V
K
S
E
D
Q
P
G
E
E
Site 5
T72
D
E
R
G
A
D
A
T
W
D
L
D
L
L
L
Site 6
T80
W
D
L
D
L
L
L
T
N
F
S
G
P
E
P
Site 7
S83
D
L
L
L
T
N
F
S
G
P
E
P
G
G
A
Site 8
T93
E
P
G
G
A
P
Q
T
C
A
L
A
P
S
E
Site 9
Y106
S
E
A
S
G
A
Q
Y
P
P
P
P
E
T
L
Site 10
T112
Q
Y
P
P
P
P
E
T
L
G
A
Y
A
G
G
Site 11
S133
L
L
G
S
E
D
H
S
G
W
V
R
P
A
L
Site 12
S178
P
G
P
G
A
G
S
S
G
G
Y
F
P
R
T
Site 13
Y181
G
A
G
S
S
G
G
Y
F
P
R
T
G
L
S
Site 14
T185
S
G
G
Y
F
P
R
T
G
L
S
V
P
A
A
Site 15
Y203
P
Y
G
L
L
S
G
Y
P
A
M
Y
P
A
P
Site 16
Y207
L
S
G
Y
P
A
M
Y
P
A
P
Q
Y
Q
G
Site 17
Y212
A
M
Y
P
A
P
Q
Y
Q
G
H
F
Q
L
F
Site 18
T231
G
P
A
P
G
P
A
T
S
P
S
F
L
S
C
Site 19
S264
V
I
A
E
T
A
P
S
K
R
G
R
R
S
W
Site 20
S270
P
S
K
R
G
R
R
S
W
A
R
K
R
Q
A
Site 21
T280
R
K
R
Q
A
A
H
T
C
A
H
P
G
C
G
Site 22
S289
A
H
P
G
C
G
K
S
Y
T
K
S
S
H
L
Site 23
Y290
H
P
G
C
G
K
S
Y
T
K
S
S
H
L
K
Site 24
T291
P
G
C
G
K
S
Y
T
K
S
S
H
L
K
A
Site 25
S293
C
G
K
S
Y
T
K
S
S
H
L
K
A
H
L
Site 26
S294
G
K
S
Y
T
K
S
S
H
L
K
A
H
L
R
Site 27
T302
H
L
K
A
H
L
R
T
H
T
G
E
K
P
Y
Site 28
T304
K
A
H
L
R
T
H
T
G
E
K
P
Y
A
C
Site 29
Y309
T
H
T
G
E
K
P
Y
A
C
T
W
E
G
C
Site 30
T327
F
A
R
S
D
E
L
T
R
H
Y
R
K
H
T
Site 31
Y330
S
D
E
L
T
R
H
Y
R
K
H
T
G
Q
R
Site 32
T334
T
R
H
Y
R
K
H
T
G
Q
R
P
F
R
C
Site 33
S349
Q
L
C
P
R
A
F
S
R
S
D
H
L
A
L
Site 34
S351
C
P
R
A
F
S
R
S
D
H
L
A
L
H
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation