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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MPP3
Full Name:
MAGUK p55 subfamily member 3
Alias:
Discs large homolog 3; Discs, large 3; DLG3; Membrane protein palmitoylated 3; Membrane protein, palmitoylated 3; Protein MPP3
Type:
Integral plasma membrane, Cell surface protein
Mass (Da):
66152
Number AA:
585
UniProt ID:
Q13368
International Prot ID:
IPI00396236
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0009986
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0004385
PhosphoSite+
KinaseNET
Biological Process:
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
E
T
L
A
L
L
T
S
Q
L
R
P
D
S
N
Site 2
S25
T
S
Q
L
R
P
D
S
N
H
K
E
E
M
G
Site 3
S39
G
F
L
R
D
V
F
S
E
K
S
L
S
Y
L
Site 4
S42
R
D
V
F
S
E
K
S
L
S
Y
L
M
K
I
Site 5
S44
V
F
S
E
K
S
L
S
Y
L
M
K
I
H
E
Site 6
Y55
K
I
H
E
K
L
R
Y
Y
E
R
Q
S
P
T
Site 7
Y56
I
H
E
K
L
R
Y
Y
E
R
Q
S
P
T
P
Site 8
S60
L
R
Y
Y
E
R
Q
S
P
T
P
V
L
H
S
Site 9
T62
Y
Y
E
R
Q
S
P
T
P
V
L
H
S
A
V
Site 10
S86
L
Q
A
A
S
V
H
S
D
E
R
E
L
L
Q
Site 11
S134
D
E
D
F
D
E
E
S
V
K
I
V
R
L
V
Site 12
T150
N
K
E
P
L
G
A
T
I
R
R
D
E
H
S
Site 13
S157
T
I
R
R
D
E
H
S
G
A
V
V
V
A
R
Site 14
S174
R
G
G
A
A
D
R
S
G
L
V
H
V
G
D
Site 15
S200
H
K
R
P
D
E
I
S
Q
I
L
A
Q
S
Q
Site 16
Y237
F
M
R
A
L
F
H
Y
N
P
R
E
D
R
A
Site 17
S264
R
Q
V
L
E
V
V
S
Q
D
D
P
T
W
W
Site 18
S288
L
R
A
G
L
I
P
S
K
G
F
Q
E
R
R
Site 19
S297
G
F
Q
E
R
R
L
S
Y
R
R
A
A
G
T
Site 20
Y298
F
Q
E
R
R
L
S
Y
R
R
A
A
G
T
L
Site 21
T304
S
Y
R
R
A
A
G
T
L
P
S
P
Q
S
L
Site 22
S307
R
A
A
G
T
L
P
S
P
Q
S
L
R
K
P
Site 23
S310
G
T
L
P
S
P
Q
S
L
R
K
P
P
Y
D
Site 24
Y316
Q
S
L
R
K
P
P
Y
D
Q
P
C
D
K
E
Site 25
Y335
E
G
Y
L
K
G
H
Y
V
A
G
L
R
R
S
Site 26
S342
Y
V
A
G
L
R
R
S
F
R
L
G
C
R
E
Site 27
S354
C
R
E
R
L
G
G
S
Q
E
G
K
M
S
S
Site 28
S360
G
S
Q
E
G
K
M
S
S
G
A
E
S
P
E
Site 29
S361
S
Q
E
G
K
M
S
S
G
A
E
S
P
E
L
Site 30
S365
K
M
S
S
G
A
E
S
P
E
L
L
T
Y
E
Site 31
Y371
E
S
P
E
L
L
T
Y
E
E
V
A
R
Y
Q
Site 32
Y377
T
Y
E
E
V
A
R
Y
Q
H
Q
P
G
E
R
Site 33
T420
F
G
V
A
V
P
H
T
T
R
P
R
K
S
H
Site 34
T421
G
V
A
V
P
H
T
T
R
P
R
K
S
H
E
Site 35
S426
H
T
T
R
P
R
K
S
H
E
K
E
G
V
E
Site 36
Y434
H
E
K
E
G
V
E
Y
H
F
V
S
K
Q
A
Site 37
S438
G
V
E
Y
H
F
V
S
K
Q
A
F
E
A
D
Site 38
Y457
K
F
L
E
H
G
E
Y
K
E
N
L
Y
G
T
Site 39
Y462
G
E
Y
K
E
N
L
Y
G
T
S
L
E
A
I
Site 40
T493
E
A
L
K
Q
L
R
T
S
E
F
K
P
Y
I
Site 41
S494
A
L
K
Q
L
R
T
S
E
F
K
P
Y
I
I
Site 42
Y499
R
T
S
E
F
K
P
Y
I
I
F
V
K
P
A
Site 43
T513
A
I
Q
E
K
R
K
T
P
P
M
S
P
A
C
Site 44
S517
K
R
K
T
P
P
M
S
P
A
C
E
D
T
A
Site 45
T523
M
S
P
A
C
E
D
T
A
A
P
F
D
E
Q
Site 46
S563
E
D
L
Q
G
A
Y
S
Q
L
K
V
V
L
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation