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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UNC119
Full Name:
Protein unc-119 homolog A
Alias:
HRG4; Retinal 4; Retinal protein 4; RG4; UN119; Unc-119
Type:
Adaptor/scaffold
Mass (Da):
26962
Number AA:
240
UniProt ID:
Q13432
International Prot ID:
IPI00013262
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000267
GO:0005625
GO:0005829
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0003008
GO:0007154
GO:0007267
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
K
G
G
G
G
A
G
T
A
T
E
S
A
P
G
Site 2
T14
G
G
G
A
G
T
A
T
E
S
A
P
G
P
S
Site 3
S16
G
A
G
T
A
T
E
S
A
P
G
P
S
G
Q
Site 4
S24
A
P
G
P
S
G
Q
S
V
A
P
I
P
Q
P
Site 5
S35
I
P
Q
P
P
A
E
S
E
S
G
S
E
S
E
Site 6
S37
Q
P
P
A
E
S
E
S
G
S
E
S
E
P
D
Site 7
S39
P
A
E
S
E
S
G
S
E
S
E
P
D
A
G
Site 8
S41
E
S
E
S
G
S
E
S
E
P
D
A
G
P
G
Site 9
Y75
L
Q
R
I
T
G
D
Y
L
C
S
P
E
E
N
Site 10
S78
I
T
G
D
Y
L
C
S
P
E
E
N
I
Y
K
Site 11
Y84
C
S
P
E
E
N
I
Y
K
I
D
F
V
R
F
Site 12
S98
F
K
I
R
D
M
D
S
G
T
V
L
F
E
I
Site 13
T100
I
R
D
M
D
S
G
T
V
L
F
E
I
K
K
Site 14
S111
E
I
K
K
P
P
V
S
E
R
L
P
I
N
R
Site 15
T134
R
F
V
R
Y
Q
F
T
P
A
F
L
R
L
R
Site 16
T146
R
L
R
Q
V
G
A
T
V
E
F
T
V
G
D
Site 17
T150
V
G
A
T
V
E
F
T
V
G
D
K
P
V
N
Site 18
Y166
F
R
M
I
E
R
H
Y
F
R
N
Q
L
L
K
Site 19
Y194
K
N
T
C
E
H
I
Y
D
F
P
P
L
S
E
Site 20
S200
I
Y
D
F
P
P
L
S
E
E
L
I
S
E
M
Site 21
S205
P
L
S
E
E
L
I
S
E
M
I
R
H
P
Y
Site 22
Y212
S
E
M
I
R
H
P
Y
E
T
Q
S
D
S
F
Site 23
S216
R
H
P
Y
E
T
Q
S
D
S
F
Y
F
V
D
Site 24
S218
P
Y
E
T
Q
S
D
S
F
Y
F
V
D
D
R
Site 25
Y220
E
T
Q
S
D
S
F
Y
F
V
D
D
R
L
V
Site 26
Y234
V
M
H
N
K
A
D
Y
S
Y
S
G
T
P
_
Site 27
Y236
H
N
K
A
D
Y
S
Y
S
G
T
P
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation