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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ADAM9
Full Name:
Disintegrin and metalloproteinase domain-containing protein 9
Alias:
A disintegrin and metalloproteinase domain 9; ADAM metallopeptidase domain 9; Cellular disintegrin-related protein; Disintegrin and metalloproteinase domain-containing protein 9: Metalloprotease/disintegrin/cysteine-rich protein 9: Myeloma cell metalloproteinase: Meltrin-gamma: Cellular disintegrin-related protein; KIAA0021; MCMP; MDC9; Meltrin gamma; Metalloprotease/disintegrin/cysteine-rich protein 9; Mltng; Myeloma cell metalloproteinase
Type:
EC 3.4.24.-; Protease
Mass (Da):
90556
Number AA:
819
UniProt ID:
Q13443
International Prot ID:
IPI00440932
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005615
GO:0016021
GO:0031233
Uniprot
OncoNet
Molecular Function:
GO:0017124
GO:0005518
GO:0005178
PhosphoSite+
KinaseNET
Biological Process:
GO:0051088
GO:0000186
GO:0033631
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
G
S
G
A
R
F
P
S
G
T
L
R
V
R
W
Site 2
Y213
A
V
L
P
Q
T
R
Y
V
E
L
F
I
V
V
Site 3
S726
K
R
D
Q
L
W
R
S
Y
F
R
K
K
R
S
Site 4
Y727
R
D
Q
L
W
R
S
Y
F
R
K
K
R
S
Q
Site 5
S733
S
Y
F
R
K
K
R
S
Q
T
Y
E
S
D
G
Site 6
T735
F
R
K
K
R
S
Q
T
Y
E
S
D
G
K
N
Site 7
Y736
R
K
K
R
S
Q
T
Y
E
S
D
G
K
N
Q
Site 8
S738
K
R
S
Q
T
Y
E
S
D
G
K
N
Q
A
N
Site 9
S747
G
K
N
Q
A
N
P
S
R
Q
P
G
S
V
P
Site 10
S752
N
P
S
R
Q
P
G
S
V
P
R
H
V
S
P
Site 11
S758
G
S
V
P
R
H
V
S
P
V
T
P
P
R
E
Site 12
T761
P
R
H
V
S
P
V
T
P
P
R
E
V
P
I
Site 13
Y769
P
P
R
E
V
P
I
Y
A
N
R
F
A
V
P
Site 14
T777
A
N
R
F
A
V
P
T
Y
A
A
K
Q
P
Q
Site 15
Y778
N
R
F
A
V
P
T
Y
A
A
K
Q
P
Q
Q
Site 16
S788
K
Q
P
Q
Q
F
P
S
R
P
P
P
P
Q
P
Site 17
S799
P
P
Q
P
K
V
S
S
Q
G
N
L
I
P
A
Site 18
Y815
P
A
P
A
P
P
L
Y
S
S
L
T
_
_
_
Site 19
S816
A
P
A
P
P
L
Y
S
S
L
T
_
_
_
_
Site 20
S817
P
A
P
P
L
Y
S
S
L
T
_
_
_
_
_
Site 21
T819
P
P
L
Y
S
S
L
T
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation