PhosphoNET

           
Protein Info 
   
Short Name:  ADAM15
Full Name:  Disintegrin and metalloproteinase domain-containing protein 15
Alias:  Metalloprotease RGD disintegrin protein;Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15;Metargidin
Type:  Adhesion protein
Mass (Da):  87717
Number AA:  814
UniProt ID:  Q13444
International Prot ID:  IPI00013302
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016021     Uniprot OncoNet
Molecular Function:  GO:0017124  GO:0004222  GO:0008270 PhosphoSite+ KinaseNET
Biological Process:  GO:0007160  GO:0006508   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S20GAGSPLPSWPLPNIG
Site 2S56LQDDLPISLKKVLQT
Site 3T63SLKKVLQTSLPEPLR
Site 4S79KLELDGDSHILELLQ
Site 5T96ELVPGRPTLVWYQPD
Site 6Y100GRPTLVWYQPDGTRV
Site 7T105VWYQPDGTRVVSEGH
Site 8S109PDGTRVVSEGHTLEN
Site 9T113RVVSEGHTLENCCYQ
Site 10Y119HTLENCCYQGRVRGY
Site 11Y126YQGRVRGYAGSWVSI
Site 12Y151VLTPERSYTLEQGPG
Site 13T152LTPERSYTLEQGPGD
Site 14S182PGHTCALSWRESVHT
Site 15S186CALSWRESVHTQTPP
Site 16T189SWRESVHTQTPPEHP
Site 17T191RESVHTQTPPEHPLG
Site 18Y715LVMLGASYWYRARLH
Site 19Y735LKGPTCQYRAAQSGP
Site 20S743RAAQSGPSERPGPPQ
Site 21T758RALLARGTKSQGPAK
Site 22S760LLARGTKSQGPAKPP
Site 23S783DPQGRCPSGDLPGPG
Site 24S800IPPLVVPSRPAPPPP
Site 25T808RPAPPPPTVSSLYL_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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