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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DRP2
Full Name:
Dystrophin-related protein 2
Alias:
Type:
Cytoskeleton protein
Mass (Da):
107962
Number AA:
957
UniProt ID:
Q13474
International Prot ID:
IPI00298753
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0007417
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S28
A
A
D
Q
F
H
H
S
S
S
L
R
S
T
C
Site 2
S29
A
D
Q
F
H
H
S
S
S
L
R
S
T
C
P
Site 3
S30
D
Q
F
H
H
S
S
S
L
R
S
T
C
P
H
Site 4
S33
H
H
S
S
S
L
R
S
T
C
P
H
P
Q
V
Site 5
T34
H
S
S
S
L
R
S
T
C
P
H
P
Q
V
R
Site 6
S46
Q
V
R
A
A
V
T
S
P
A
P
P
Q
D
G
Site 7
S71
L
N
G
S
V
G
A
S
G
P
L
E
P
P
A
Site 8
S101
R
A
R
L
E
A
F
S
D
H
S
G
K
L
Q
Site 9
S119
Q
E
I
I
D
W
L
S
Q
K
D
E
E
L
S
Site 10
S126
S
Q
K
D
E
E
L
S
A
Q
L
P
L
Q
G
Site 11
S154
A
F
M
E
E
V
K
S
R
G
P
Y
I
Y
S
Site 12
Y158
E
V
K
S
R
G
P
Y
I
Y
S
V
L
E
S
Site 13
Y160
K
S
R
G
P
Y
I
Y
S
V
L
E
S
A
Q
Site 14
S161
S
R
G
P
Y
I
Y
S
V
L
E
S
A
Q
A
Site 15
S171
E
S
A
Q
A
F
L
S
Q
H
P
F
E
E
L
Site 16
S183
E
E
L
E
E
P
H
S
E
S
K
D
T
S
P
Site 17
S185
L
E
E
P
H
S
E
S
K
D
T
S
P
K
Q
Site 18
T188
P
H
S
E
S
K
D
T
S
P
K
Q
R
I
Q
Site 19
S189
H
S
E
S
K
D
T
S
P
K
Q
R
I
Q
N
Site 20
T206
R
F
V
W
K
Q
A
T
V
A
S
E
L
W
E
Site 21
T216
S
E
L
W
E
K
L
T
A
R
C
V
D
Q
H
Site 22
T229
Q
H
R
H
I
E
R
T
L
E
Q
L
L
E
I
Site 23
S244
Q
G
A
M
E
E
L
S
T
T
L
S
Q
A
E
Site 24
T245
G
A
M
E
E
L
S
T
T
L
S
Q
A
E
G
Site 25
T246
A
M
E
E
L
S
T
T
L
S
Q
A
E
G
V
Site 26
S248
E
E
L
S
T
T
L
S
Q
A
E
G
V
R
A
Site 27
T256
Q
A
E
G
V
R
A
T
W
E
P
I
G
D
L
Site 28
S283
K
L
F
K
E
E
F
S
P
M
K
D
G
V
K
Site 29
S307
A
I
S
D
V
H
L
S
M
E
N
S
Q
A
L
Site 30
S311
V
H
L
S
M
E
N
S
Q
A
L
E
Q
I
N
Site 31
S327
R
W
K
Q
L
Q
A
S
V
S
E
R
L
K
Q
Site 32
S329
K
Q
L
Q
A
S
V
S
E
R
L
K
Q
L
Q
Site 33
S346
H
R
D
F
G
P
G
S
Q
H
F
L
S
S
S
Site 34
S351
P
G
S
Q
H
F
L
S
S
S
V
Q
V
P
W
Site 35
S353
S
Q
H
F
L
S
S
S
V
Q
V
P
W
E
R
Site 36
S363
V
P
W
E
R
A
I
S
P
N
K
V
P
Y
Y
Site 37
Y370
S
P
N
K
V
P
Y
Y
I
N
H
Q
A
Q
T
Site 38
T391
K
M
T
E
L
Y
Q
T
L
A
D
L
N
N
I
Site 39
T405
I
K
F
S
A
Y
R
T
A
M
K
L
R
R
V
Site 40
Y455
I
H
C
L
T
A
L
Y
E
R
L
E
E
E
R
Site 41
S485
W
L
L
N
V
F
D
S
G
R
S
G
K
M
R
Site 42
T498
M
R
A
L
S
F
K
T
G
I
A
C
L
C
G
Site 43
Y514
E
V
K
E
K
L
Q
Y
L
F
S
Q
V
A
N
Site 44
S517
E
K
L
Q
Y
L
F
S
Q
V
A
N
S
G
S
Site 45
S522
L
F
S
Q
V
A
N
S
G
S
Q
C
D
Q
R
Site 46
S524
S
Q
V
A
N
S
G
S
Q
C
D
Q
R
H
L
Site 47
S559
G
G
S
N
V
E
P
S
V
R
S
C
F
R
F
Site 48
S562
N
V
E
P
S
V
R
S
C
F
R
F
S
T
G
Site 49
S567
V
R
S
C
F
R
F
S
T
G
K
P
V
I
E
Site 50
T568
R
S
C
F
R
F
S
T
G
K
P
V
I
E
A
Site 51
S576
G
K
P
V
I
E
A
S
Q
F
L
E
W
V
N
Site 52
S588
W
V
N
L
E
P
Q
S
M
V
W
L
A
V
L
Site 53
S625
I
K
G
F
R
Y
R
S
L
K
Q
F
N
V
D
Site 54
T640
I
C
Q
T
C
F
L
T
G
R
A
S
K
G
N
Site 55
S644
C
F
L
T
G
R
A
S
K
G
N
K
L
H
Y
Site 56
Y651
S
K
G
N
K
L
H
Y
P
I
M
E
Y
Y
T
Site 57
Y656
L
H
Y
P
I
M
E
Y
Y
T
P
T
T
S
S
Site 58
Y657
H
Y
P
I
M
E
Y
Y
T
P
T
T
S
S
E
Site 59
T658
Y
P
I
M
E
Y
Y
T
P
T
T
S
S
E
N
Site 60
T672
N
M
R
D
F
A
T
T
L
K
N
K
F
R
S
Site 61
Y682
N
K
F
R
S
K
H
Y
F
S
K
H
P
Q
R
Site 62
S684
F
R
S
K
H
Y
F
S
K
H
P
Q
R
G
Y
Site 63
Y691
S
K
H
P
Q
R
G
Y
L
P
V
Q
S
V
L
Site 64
S696
R
G
Y
L
P
V
Q
S
V
L
E
A
D
Y
S
Site 65
Y702
Q
S
V
L
E
A
D
Y
S
E
T
P
A
S
S
Site 66
S703
S
V
L
E
A
D
Y
S
E
T
P
A
S
S
P
Site 67
T705
L
E
A
D
Y
S
E
T
P
A
S
S
P
M
W
Site 68
S708
D
Y
S
E
T
P
A
S
S
P
M
W
P
H
A
Site 69
S709
Y
S
E
T
P
A
S
S
P
M
W
P
H
A
D
Site 70
T717
P
M
W
P
H
A
D
T
H
S
R
I
E
H
F
Site 71
S719
W
P
H
A
D
T
H
S
R
I
E
H
F
A
S
Site 72
S726
S
R
I
E
H
F
A
S
R
L
A
E
M
E
S
Site 73
S733
S
R
L
A
E
M
E
S
Q
N
C
S
F
F
N
Site 74
S737
E
M
E
S
Q
N
C
S
F
F
N
D
S
L
S
Site 75
S742
N
C
S
F
F
N
D
S
L
S
P
D
D
S
I
Site 76
S744
S
F
F
N
D
S
L
S
P
D
D
S
I
D
E
Site 77
S748
D
S
L
S
P
D
D
S
I
D
E
D
Q
Y
L
Site 78
Y754
D
S
I
D
E
D
Q
Y
L
L
R
H
S
S
P
Site 79
S759
D
Q
Y
L
L
R
H
S
S
P
I
T
D
R
E
Site 80
S760
Q
Y
L
L
R
H
S
S
P
I
T
D
R
E
P
Site 81
T763
L
R
H
S
S
P
I
T
D
R
E
P
A
F
G
Site 82
S776
F
G
Q
Q
A
P
C
S
V
A
T
E
S
K
G
Site 83
S818
E
E
A
A
E
A
P
S
L
A
D
G
S
T
E
Site 84
T824
P
S
L
A
D
G
S
T
E
A
A
T
D
H
R
Site 85
T828
D
G
S
T
E
A
A
T
D
H
R
N
E
E
L
Site 86
S847
R
I
L
R
Q
H
K
S
R
L
E
T
R
M
Q
Site 87
T851
Q
H
K
S
R
L
E
T
R
M
Q
I
L
E
D
Site 88
S865
D
H
N
K
Q
L
E
S
Q
L
Q
R
L
R
E
Site 89
T879
E
L
L
L
Q
P
P
T
E
S
D
G
S
G
S
Site 90
S881
L
L
Q
P
P
T
E
S
D
G
S
G
S
A
G
Site 91
S884
P
P
T
E
S
D
G
S
G
S
A
G
S
S
L
Site 92
S886
T
E
S
D
G
S
G
S
A
G
S
S
L
A
S
Site 93
S889
D
G
S
G
S
A
G
S
S
L
A
S
S
P
Q
Site 94
S890
G
S
G
S
A
G
S
S
L
A
S
S
P
Q
Q
Site 95
S893
S
A
G
S
S
L
A
S
S
P
Q
Q
S
E
G
Site 96
S894
A
G
S
S
L
A
S
S
P
Q
Q
S
E
G
S
Site 97
S898
L
A
S
S
P
Q
Q
S
E
G
S
H
P
R
E
Site 98
S901
S
P
Q
Q
S
E
G
S
H
P
R
E
K
G
Q
Site 99
T909
H
P
R
E
K
G
Q
T
T
P
D
T
E
A
A
Site 100
T910
P
R
E
K
G
Q
T
T
P
D
T
E
A
A
D
Site 101
T913
K
G
Q
T
T
P
D
T
E
A
A
D
D
V
G
Site 102
S923
A
D
D
V
G
S
K
S
Q
D
V
S
L
C
L
Site 103
S927
G
S
K
S
Q
D
V
S
L
C
L
E
D
I
M
Site 104
S943
K
L
R
H
A
F
P
S
V
R
S
S
D
V
T
Site 105
S947
A
F
P
S
V
R
S
S
D
V
T
A
N
T
L
Site 106
T950
S
V
R
S
S
D
V
T
A
N
T
L
L
A
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation