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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TCIRG1
Full Name:
V-type proton ATPase 116 kDa subunit a isoform 3
Alias:
A3; Atp6i; Atp6n1c; Atp6v0a3; Oc116; Oc-116kda; Optb1; Stv1; T-cell, immune regulator 1; T-cell, immune regulator 1 isoform a; T-cell, immune regulator 1 isoform b; T-cell, immune regulator 1, Atpase, h+ transporting, lysosomal v0 subunit a3; Tcirg1; Tirc7; Tirc7 protein; Vph1; Vpp3
Type:
Mass (Da):
92998
Number AA:
830
UniProt ID:
Q13488
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016324
GO:0005887
GO:0033177
Uniprot
OncoNet
Molecular Function:
GO:0015078
PhosphoSite+
KinaseNET
Biological Process:
GO:0015986
GO:0006968
GO:0008284
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S43
E
F
R
D
L
N
A
S
V
S
A
F
Q
R
R
Site 2
S45
R
D
L
N
A
S
V
S
A
F
Q
R
R
F
V
Site 3
T64
R
C
E
E
L
E
K
T
F
T
F
L
Q
E
E
Site 4
T66
E
E
L
E
K
T
F
T
F
L
Q
E
E
V
R
Site 5
T101
L
L
R
I
Q
E
E
T
E
R
L
A
Q
E
L
Site 6
T145
P
Q
L
A
A
A
H
T
D
G
A
S
E
R
T
Site 7
S149
A
A
H
T
D
G
A
S
E
R
T
P
L
L
Q
Site 8
T152
T
D
G
A
S
E
R
T
P
L
L
Q
A
P
G
Site 9
S197
C
R
G
F
L
I
A
S
F
R
E
L
E
Q
P
Site 10
T210
Q
P
L
E
H
P
V
T
G
E
P
A
T
W
M
Site 11
T274
L
Q
E
V
L
G
E
T
E
R
F
L
S
Q
V
Site 12
S279
G
E
T
E
R
F
L
S
Q
V
L
G
R
V
L
Site 13
T314
N
Q
C
S
V
S
T
T
H
K
C
L
I
A
E
Site 14
S339
L
Q
E
A
L
R
D
S
S
M
E
E
G
V
S
Site 15
S340
Q
E
A
L
R
D
S
S
M
E
E
G
V
S
A
Site 16
S346
S
S
M
E
E
G
V
S
A
V
A
H
R
I
P
Site 17
T360
P
C
R
D
M
P
P
T
L
I
R
T
N
R
F
Site 18
T364
M
P
P
T
L
I
R
T
N
R
F
T
A
S
F
Site 19
S370
R
T
N
R
F
T
A
S
F
Q
G
I
V
D
A
Site 20
Y378
F
Q
G
I
V
D
A
Y
G
V
G
R
Y
Q
E
Site 21
Y383
D
A
Y
G
V
G
R
Y
Q
E
V
N
P
A
P
Site 22
Y461
S
I
Y
T
G
F
I
Y
N
E
C
F
S
R
A
Site 23
T469
N
E
C
F
S
R
A
T
S
I
F
P
S
G
W
Site 24
S470
E
C
F
S
R
A
T
S
I
F
P
S
G
W
S
Site 25
S532
N
H
L
S
F
L
N
S
F
K
M
K
M
S
V
Site 26
S619
N
M
F
L
F
S
H
S
P
S
N
R
L
L
Y
Site 27
S621
F
L
F
S
H
S
P
S
N
R
L
L
Y
P
R
Site 28
Y626
S
P
S
N
R
L
L
Y
P
R
Q
E
V
V
Q
Site 29
S685
L
L
D
L
P
D
A
S
V
N
G
W
S
S
D
Site 30
S691
A
S
V
N
G
W
S
S
D
E
E
K
A
G
G
Site 31
S710
E
E
A
E
L
V
P
S
E
V
L
M
H
Q
A
Site 32
Y818
K
F
Y
S
G
T
G
Y
K
L
S
P
F
T
F
Site 33
S821
S
G
T
G
Y
K
L
S
P
F
T
F
A
A
T
Site 34
T824
G
Y
K
L
S
P
F
T
F
A
A
T
D
D
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation