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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TrpC3
Full Name:
Short transient receptor potential channel 3
Alias:
Htrp3; Htrp-3; Transient receptor potential cation channel, subfamily C, member 3; TRP3
Type:
Channel protein
Mass (Da):
97355
Number AA:
848
UniProt ID:
Q13507
International Prot ID:
IPI00748783
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005515
GO:0015279
PhosphoSite+
KinaseNET
Biological Process:
GO:0006816
GO:0007602
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
S
P
S
L
R
R
M
T
V
M
R
E
K
G
R
Site 2
T34
F
M
F
N
D
R
G
T
S
L
T
A
E
E
E
Site 3
S35
M
F
N
D
R
G
T
S
L
T
A
E
E
E
R
Site 4
T37
N
D
R
G
T
S
L
T
A
E
E
E
R
F
L
Site 5
Y49
R
F
L
D
A
A
E
Y
G
N
I
P
V
V
R
Site 6
T64
K
M
L
E
E
S
K
T
L
N
V
N
C
V
D
Site 7
Y72
L
N
V
N
C
V
D
Y
M
G
Q
N
A
L
Q
Site 8
S130
N
H
P
G
F
A
A
S
K
R
L
T
L
S
P
Site 9
T134
F
A
A
S
K
R
L
T
L
S
P
C
E
Q
E
Site 10
S136
A
S
K
R
L
T
L
S
P
C
E
Q
E
L
Q
Site 11
Y148
E
L
Q
D
D
D
F
Y
A
Y
D
E
D
G
T
Site 12
Y150
Q
D
D
D
F
Y
A
Y
D
E
D
G
T
R
F
Site 13
S158
D
E
D
G
T
R
F
S
P
D
I
T
P
I
I
Site 14
Y192
R
I
E
R
P
H
D
Y
F
C
K
C
G
D
C
Site 15
S207
M
E
K
Q
R
H
D
S
F
S
H
S
R
S
R
Site 16
S209
K
Q
R
H
D
S
F
S
H
S
R
S
R
I
N
Site 17
S211
R
H
D
S
F
S
H
S
R
S
R
I
N
A
Y
Site 18
S213
D
S
F
S
H
S
R
S
R
I
N
A
Y
K
G
Site 19
S223
N
A
Y
K
G
L
A
S
P
A
Y
L
S
L
S
Site 20
Y226
K
G
L
A
S
P
A
Y
L
S
L
S
S
E
D
Site 21
S230
S
P
A
Y
L
S
L
S
S
E
D
P
V
L
T
Site 22
Y259
E
K
E
F
K
N
D
Y
R
K
L
S
M
Q
C
Site 23
S263
K
N
D
Y
R
K
L
S
M
Q
C
K
D
F
V
Site 24
S293
I
L
N
G
D
L
E
S
A
E
P
L
E
V
H
Site 25
S305
E
V
H
R
H
K
A
S
L
S
R
V
K
L
A
Site 26
S307
H
R
H
K
A
S
L
S
R
V
K
L
A
I
K
Site 27
Y335
Q
Q
L
L
T
I
W
Y
E
N
L
S
G
L
R
Site 28
S339
T
I
W
Y
E
N
L
S
G
L
R
E
Q
T
I
Site 29
T412
S
D
R
F
E
G
I
T
T
L
P
N
I
T
V
Site 30
T413
D
R
F
E
G
I
T
T
L
P
N
I
T
V
T
Site 31
T418
I
T
T
L
P
N
I
T
V
T
D
Y
P
K
Q
Site 32
T420
T
L
P
N
I
T
V
T
D
Y
P
K
Q
I
F
Site 33
Y422
P
N
I
T
V
T
D
Y
P
K
Q
I
F
R
V
Site 34
T431
K
Q
I
F
R
V
K
T
T
Q
F
T
W
T
E
Site 35
Y464
W
L
E
G
P
R
E
Y
I
L
Q
L
W
N
V
Site 36
Y500
Q
A
T
K
A
Q
Q
Y
V
D
S
Y
V
Q
E
Site 37
S503
K
A
Q
Q
Y
V
D
S
Y
V
Q
E
S
D
L
Site 38
Y504
A
Q
Q
Y
V
D
S
Y
V
Q
E
S
D
L
S
Site 39
S511
Y
V
Q
E
S
D
L
S
E
V
T
L
P
P
E
Site 40
T514
E
S
D
L
S
E
V
T
L
P
P
E
I
Q
Y
Site 41
Y521
T
L
P
P
E
I
Q
Y
F
T
Y
A
R
D
K
Site 42
Y524
P
E
I
Q
Y
F
T
Y
A
R
D
K
W
L
P
Site 43
S532
A
R
D
K
W
L
P
S
D
P
Q
I
I
S
E
Site 44
S569
S
F
G
P
L
Q
I
S
L
G
R
T
V
K
D
Site 45
T613
K
V
N
A
A
F
T
T
V
E
E
S
F
K
T
Site 46
Y638
V
T
S
V
V
L
K
Y
D
H
K
F
I
E
N
Site 47
S673
L
I
A
M
I
N
S
S
Y
Q
E
I
E
D
D
Site 48
S681
Y
Q
E
I
E
D
D
S
D
V
E
W
K
F
A
Site 49
S695
A
R
S
K
L
W
L
S
Y
F
D
D
G
K
T
Site 50
Y696
R
S
K
L
W
L
S
Y
F
D
D
G
K
T
L
Site 51
T702
S
Y
F
D
D
G
K
T
L
P
P
P
F
S
L
Site 52
S708
K
T
L
P
P
P
F
S
L
V
P
S
P
K
S
Site 53
S712
P
P
F
S
L
V
P
S
P
K
S
F
V
Y
F
Site 54
S745
I
E
M
G
M
G
N
S
K
S
R
L
N
L
F
Site 55
S747
M
G
M
G
N
S
K
S
R
L
N
L
F
T
Q
Site 56
T753
K
S
R
L
N
L
F
T
Q
S
N
S
R
V
F
Site 57
S755
R
L
N
L
F
T
Q
S
N
S
R
V
F
E
S
Site 58
S757
N
L
F
T
Q
S
N
S
R
V
F
E
S
H
S
Site 59
S762
S
N
S
R
V
F
E
S
H
S
F
N
S
I
L
Site 60
S764
S
R
V
F
E
S
H
S
F
N
S
I
L
N
Q
Site 61
Y786
M
K
R
L
I
K
R
Y
V
L
K
A
Q
V
D
Site 62
S813
E
I
K
Q
D
I
S
S
L
R
Y
E
L
L
E
Site 63
S823
Y
E
L
L
E
D
K
S
Q
A
T
E
E
L
A
Site 64
S843
L
S
E
K
L
N
P
S
M
L
R
C
E
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation