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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ASAH1
Full Name:
Acid ceramidase
Alias:
Acylsphingosine deacylase;N-acylsphingosine amidohydrolase;Putative 32 kDa heart protein
Type:
Mass (Da):
44660
Number AA:
395
UniProt ID:
Q13510
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S34
W
T
E
D
C
R
K
S
T
Y
P
P
S
G
P
Site 2
T35
T
E
D
C
R
K
S
T
Y
P
P
S
G
P
T
Site 3
Y36
E
D
C
R
K
S
T
Y
P
P
S
G
P
T
Y
Site 4
S39
R
K
S
T
Y
P
P
S
G
P
T
Y
R
G
A
Site 5
T42
T
Y
P
P
S
G
P
T
Y
R
G
A
V
P
W
Site 6
Y43
Y
P
P
S
G
P
T
Y
R
G
A
V
P
W
Y
Site 7
Y50
Y
R
G
A
V
P
W
Y
T
I
N
L
D
L
P
Site 8
T51
R
G
A
V
P
W
Y
T
I
N
L
D
L
P
P
Site 9
Y59
I
N
L
D
L
P
P
Y
K
R
W
H
E
L
M
Site 10
S90
M
I
N
T
F
V
P
S
G
K
I
M
Q
V
V
Site 11
T186
T
E
Q
L
K
P
L
T
V
N
L
D
F
Q
R
Site 12
T197
D
F
Q
R
N
N
K
T
V
F
K
A
S
S
F
Site 13
S220
G
F
K
P
G
L
F
S
L
T
L
N
E
R
F
Site 14
T222
K
P
G
L
F
S
L
T
L
N
E
R
F
S
I
Site 15
S228
L
T
L
N
E
R
F
S
I
N
G
G
Y
L
G
Site 16
T253
V
M
W
I
G
F
L
T
R
T
V
L
E
N
S
Site 17
T255
W
I
G
F
L
T
R
T
V
L
E
N
S
T
S
Site 18
S262
T
V
L
E
N
S
T
S
Y
E
E
A
K
N
L
Site 19
T295
S
G
E
G
C
V
I
T
R
D
R
K
E
S
L
Site 20
S301
I
T
R
D
R
K
E
S
L
D
V
Y
E
L
D
Site 21
Y305
R
K
E
S
L
D
V
Y
E
L
D
A
K
Q
G
Site 22
Y315
D
A
K
Q
G
R
W
Y
V
V
Q
T
N
Y
D
Site 23
T335
F
F
L
D
D
R
R
T
P
A
K
M
C
L
N
Site 24
S345
K
M
C
L
N
R
T
S
Q
E
N
I
S
F
E
Site 25
S350
R
T
S
Q
E
N
I
S
F
E
T
M
Y
D
V
Site 26
Y355
N
I
S
F
E
T
M
Y
D
V
L
S
T
K
P
Site 27
S359
E
T
M
Y
D
V
L
S
T
K
P
V
L
N
K
Site 28
T360
T
M
Y
D
V
L
S
T
K
P
V
L
N
K
L
Site 29
T377
Y
T
T
L
I
D
V
T
K
G
Q
F
E
T
Y
Site 30
Y384
T
K
G
Q
F
E
T
Y
L
R
D
C
P
D
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation