PhosphoNET

           
Protein Info 
   
Short Name:  EIF4EBP2
Full Name:  Eukaryotic translation initiation factor 4E-binding protein 2
Alias:  4E-binding protein 2; 4EBP2; PHAS-II
Type:  Translation protein
Mass (Da):  12939
Number AA:  120
UniProt ID:  Q13542
International Prot ID:  IPI00002570
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:  GO:0008190     PhosphoSite+ KinaseNET
Biological Process:  GO:0045947  GO:0006412   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S4____MSSSAGSGHQP
Site 2S7_MSSSAGSGHQPSQS
Site 3S12AGSGHQPSQSRAIPT
Site 4S14SGHQPSQSRAIPTRT
Site 5S25PTRTVAISDAAQLPH
Site 6Y34AAQLPHDYCTTPGGT
Site 7T36QLPHDYCTTPGGTLF
Site 8T37LPHDYCTTPGGTLFS
Site 9T41YCTTPGGTLFSTTPG
Site 10S44TPGGTLFSTTPGGTR
Site 11T45PGGTLFSTTPGGTRI
Site 12T46GGTLFSTTPGGTRII
Site 13T50FSTTPGGTRIIYDRK
Site 14Y54PGGTRIIYDRKFLLD
Site 15S65FLLDRRNSPMAQTPP
Site 16T70RNSPMAQTPPCHLPN
Site 17S83PNIPGVTSPGTLIED
Site 18T86PGVTSPGTLIEDSKV
Site 19S91PGTLIEDSKVEVNNL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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