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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DCTN2
Full Name:
Dynactin subunit 2
Alias:
50 kDa dynein-associated polypeptide; DCT2; DCTN-50; Dynactin 2 (p50); Dynactin complex 50 kDa subunit; P50 dynamitin; RBP50
Type:
Motor protein
Mass (Da):
44231
Number AA:
401
UniProt ID:
Q13561
International Prot ID:
IPI00220503
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005813
GO:0005829
GO:0005869
Uniprot
OncoNet
Molecular Function:
GO:0003774
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0008283
GO:0007067
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y6
_
_
M
A
D
P
K
Y
A
D
L
P
G
I
A
Site 2
Y20
A
R
N
E
P
D
V
Y
E
T
S
D
L
P
E
Site 3
S23
E
P
D
V
Y
E
T
S
D
L
P
E
D
D
Q
Site 4
S40
F
D
A
E
E
L
T
S
T
S
V
E
H
I
I
Site 5
Y54
I
V
N
P
N
A
A
Y
D
K
F
K
D
K
R
Site 6
T64
F
K
D
K
R
V
G
T
K
G
L
D
F
S
D
Site 7
S70
G
T
K
G
L
D
F
S
D
R
I
G
K
T
K
Site 8
T76
F
S
D
R
I
G
K
T
K
R
T
G
Y
E
S
Site 9
T79
R
I
G
K
T
K
R
T
G
Y
E
S
G
E
Y
Site 10
Y81
G
K
T
K
R
T
G
Y
E
S
G
E
Y
E
M
Site 11
S83
T
K
R
T
G
Y
E
S
G
E
Y
E
M
L
G
Site 12
Y86
G
K
T
K
R
T
G
Y
E
S
G
E
Y
E
M
Site 13
T98
E
G
L
G
V
K
E
T
P
Q
Q
K
Y
Q
R
Site 14
Y103
K
E
T
P
Q
Q
K
Y
Q
R
L
L
H
E
V
Site 15
T122
T
E
V
E
K
I
K
T
T
V
K
E
S
A
T
Site 16
T123
E
V
E
K
I
K
T
T
V
K
E
S
A
T
E
Site 17
T134
S
A
T
E
E
K
L
T
P
V
L
L
A
K
Q
Site 18
S187
Q
L
E
A
T
K
N
S
K
G
G
S
G
G
K
Site 19
S191
T
K
N
S
K
G
G
S
G
G
K
T
T
G
T
Site 20
T195
K
G
G
S
G
G
K
T
T
G
T
P
P
D
S
Site 21
T196
G
G
S
G
G
K
T
T
G
T
P
P
D
S
S
Site 22
T198
S
G
G
K
T
T
G
T
P
P
D
S
S
L
V
Site 23
S202
T
T
G
T
P
P
D
S
S
L
V
T
Y
E
L
Site 24
S203
T
G
T
P
P
D
S
S
L
V
T
Y
E
L
H
Site 25
T206
P
P
D
S
S
L
V
T
Y
E
L
H
S
R
P
Site 26
Y207
P
D
S
S
L
V
T
Y
E
L
H
S
R
P
E
Site 27
S219
R
P
E
Q
D
K
F
S
Q
A
A
K
V
A
E
Site 28
T232
A
E
L
E
K
R
L
T
E
L
E
T
A
V
R
Site 29
S249
Q
D
A
Q
N
P
L
S
A
G
L
Q
G
A
C
Site 30
T260
Q
G
A
C
L
M
E
T
V
E
L
L
Q
A
K
Site 31
S285
Q
V
E
A
R
L
Q
S
V
L
G
K
V
N
E
Site 32
T305
A
S
V
E
D
A
D
T
Q
S
K
V
H
Q
L
Site 33
S307
V
E
D
A
D
T
Q
S
K
V
H
Q
L
Y
E
Site 34
Y313
Q
S
K
V
H
Q
L
Y
E
T
I
Q
R
W
S
Site 35
T315
K
V
H
Q
L
Y
E
T
I
Q
R
W
S
P
I
Site 36
S320
Y
E
T
I
Q
R
W
S
P
I
A
S
T
L
P
Site 37
S324
Q
R
W
S
P
I
A
S
T
L
P
E
L
V
Q
Site 38
T325
R
W
S
P
I
A
S
T
L
P
E
L
V
Q
R
Site 39
T335
E
L
V
Q
R
L
V
T
I
K
Q
L
H
E
Q
Site 40
T356
L
L
T
H
L
D
T
T
Q
Q
M
I
A
N
S
Site 41
S363
T
Q
Q
M
I
A
N
S
L
K
D
N
T
T
L
Site 42
T369
N
S
L
K
D
N
T
T
L
L
T
Q
V
Q
T
Site 43
T372
K
D
N
T
T
L
L
T
Q
V
Q
T
T
M
R
Site 44
T384
T
M
R
E
N
L
A
T
V
E
G
N
F
A
S
Site 45
S391
T
V
E
G
N
F
A
S
I
D
E
R
M
K
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation