PhosphoNET

           
Protein Info 
   
Short Name:  IRF5
Full Name:  Interferon regulatory factor 5
Alias: 
Type:  Transcription protein
Mass (Da):  56044
Number AA:  498
UniProt ID:  Q13568
International Prot ID:  IPI00396061
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634     Uniprot OncoNet
Molecular Function:  GO:0003700     PhosphoSite+ KinaseNET
Biological Process:  GO:0006355  GO:0006350   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T10QSIPVAPTPPRRVRL
Site 2T62PSQDGDNTIFKAWAK
Site 3Y74WAKETGKYTEGVDEA
Site 4S97LRCALNKSRDFRLIY
Site 5Y104SRDFRLIYDGPRDMP
Site 6Y118PPQPYKIYEVCSNGP
Site 7S130NGPAPTDSQPPEDYS
Site 8Y136DSQPPEDYSFGAGEE
Site 9S137SQPPEDYSFGAGEEE
Site 10S156ELQRMLPSLSLTEDV
Site 11S158QRMLPSLSLTEDVKW
Site 12T160MLPSLSLTEDVKWPP
Site 13T168EDVKWPPTLQPPTLR
Site 14T173PPTLQPPTLRPPTLQ
Site 15T178PPTLRPPTLQPPTLQ
Site 16S198GPPAPDPSPLAPPPG
Site 17S215AGFRELLSEVLEPGP
Site 18S226EPGPLPASLPPAGEQ
Site 19T248SPHMLPLTDLEIKFQ
Site 20T265GRPPRALTISNPHGC
Site 21S267PPRALTISNPHGCRL
Site 22Y276PHGCRLFYSQLEATQ
Site 23S277HGCRLFYSQLEATQE
Site 24S301LEQVRFPSPEDIPSD
Site 25S307PSPEDIPSDKQRFYT
Site 26Y313PSDKQRFYTNQLLDV
Site 27T314SDKQRFYTNQLLDVL
Site 28Y335QLQGQDLYAIRLCQC
Site 29S356PCASAHDSCPNPIQR
Site 30T367PIQREVKTKLFSLEH
Site 31S371EVKTKLFSLEHFLNE
Site 32T389FQKGQTNTPPPFEIF
Site 33S435EMFSGELSWSADSIR
Site 34S437FSGELSWSADSIRLQ
Site 35S440ELSWSADSIRLQISN
Site 36S446DSIRLQISNPDLKDR
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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