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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SNX1
Full Name:
Sorting nexin-1
Alias:
HsT17379; MGC8664; SNX1A; sorting nexin 1; Vps5
Type:
Vesicle protein
Mass (Da):
59070
Number AA:
522
UniProt ID:
Q13596
International Prot ID:
IPI00183530
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0035091
GO:0005515
GO:0008565
PhosphoSite+
KinaseNET
Biological Process:
GO:0007154
GO:0006897
GO:0006886
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
A
S
G
G
G
G
C
S
A
S
E
R
L
P
P
Site 2
S11
G
G
G
G
C
S
A
S
E
R
L
P
P
P
F
Site 3
S25
F
P
G
L
E
P
E
S
E
G
A
A
G
G
S
Site 4
S32
S
E
G
A
A
G
G
S
E
P
E
A
G
D
S
Site 5
S39
S
E
P
E
A
G
D
S
D
T
E
G
E
D
I
Site 6
T41
P
E
A
G
D
S
D
T
E
G
E
D
I
F
T
Site 7
T48
T
E
G
E
D
I
F
T
G
A
A
V
V
S
K
Site 8
S58
A
V
V
S
K
H
Q
S
P
K
I
T
T
S
L
Site 9
T62
K
H
Q
S
P
K
I
T
T
S
L
L
P
I
N
Site 10
S64
Q
S
P
K
I
T
T
S
L
L
P
I
N
N
G
Site 11
S72
L
L
P
I
N
N
G
S
K
E
N
G
I
H
E
Site 12
S97
A
D
A
T
V
E
L
S
L
D
S
T
Q
N
N
Site 13
T101
V
E
L
S
L
D
S
T
Q
N
N
Q
K
K
V
Site 14
T112
Q
K
K
V
L
A
K
T
L
I
S
L
P
P
Q
Site 15
T122
S
L
P
P
Q
E
A
T
N
S
S
K
P
Q
P
Site 16
S124
P
P
Q
E
A
T
N
S
S
K
P
Q
P
T
Y
Site 17
S125
P
Q
E
A
T
N
S
S
K
P
Q
P
T
Y
E
Site 18
Y131
S
S
K
P
Q
P
T
Y
E
E
L
E
E
E
E
Site 19
T146
Q
E
D
Q
F
D
L
T
V
G
I
T
D
P
E
Site 20
Y162
I
G
D
G
M
N
A
Y
V
A
Y
K
V
T
T
Site 21
S172
Y
K
V
T
T
Q
T
S
L
P
L
F
R
S
K
Site 22
S178
T
S
L
P
L
F
R
S
K
Q
F
A
V
K
R
Site 23
S188
F
A
V
K
R
R
F
S
D
F
L
G
L
Y
E
Site 24
Y194
F
S
D
F
L
G
L
Y
E
K
L
S
E
K
H
Site 25
S198
L
G
L
Y
E
K
L
S
E
K
H
S
Q
N
G
Site 26
S202
E
K
L
S
E
K
H
S
Q
N
G
F
I
V
P
Site 27
S215
V
P
P
P
P
E
K
S
L
I
G
M
T
K
V
Site 28
S229
V
K
V
G
K
E
D
S
S
S
A
E
F
L
E
Site 29
S230
K
V
G
K
E
D
S
S
S
A
E
F
L
E
K
Site 30
S231
V
G
K
E
D
S
S
S
A
E
F
L
E
K
R
Site 31
Y245
R
R
A
A
L
E
R
Y
L
Q
R
I
V
N
H
Site 32
T276
E
L
P
R
A
V
G
T
Q
T
L
S
G
A
G
Site 33
S280
A
V
G
T
Q
T
L
S
G
A
G
L
L
K
M
Site 34
T292
L
K
M
F
N
K
A
T
D
A
V
S
K
M
T
Site 35
S356
K
S
L
A
M
L
G
S
S
E
D
N
T
A
L
Site 36
T361
L
G
S
S
E
D
N
T
A
L
S
R
A
L
S
Site 37
S364
S
E
D
N
T
A
L
S
R
A
L
S
Q
L
A
Site 38
S368
T
A
L
S
R
A
L
S
Q
L
A
E
V
E
E
Site 39
T461
L
E
W
E
S
R
V
T
Q
Y
E
R
D
F
E
Site 40
Y463
W
E
S
R
V
T
Q
Y
E
R
D
F
E
R
I
Site 41
S471
E
R
D
F
E
R
I
S
T
V
V
R
K
E
V
Site 42
T472
R
D
F
E
R
I
S
T
V
V
R
K
E
V
I
Site 43
S486
I
R
F
E
K
E
K
S
K
D
F
K
N
H
V
Site 44
Y496
F
K
N
H
V
I
K
Y
L
E
T
L
L
Y
S
Site 45
T499
H
V
I
K
Y
L
E
T
L
L
Y
S
Q
Q
Q
Site 46
Y502
K
Y
L
E
T
L
L
Y
S
Q
Q
Q
L
A
K
Site 47
Y510
S
Q
Q
Q
L
A
K
Y
W
E
A
F
L
P
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation