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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MTMR1
Full Name:
Myotubularin-related protein 1
Alias:
EC 3.1.3.-
Type:
Protein phosphatase, Myotubularin related
Mass (Da):
74678
Number AA:
665
UniProt ID:
Q13613
International Prot ID:
IPI00292601
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0004725
PhosphoSite+
KinaseNET
Biological Process:
GO:0016311
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T36
P
R
A
A
G
G
A
T
A
G
S
R
Q
P
S
Site 2
S39
A
G
G
A
T
A
G
S
R
Q
P
S
V
E
T
Site 3
S43
T
A
G
S
R
Q
P
S
V
E
T
L
D
S
P
Site 4
T46
S
R
Q
P
S
V
E
T
L
D
S
P
T
G
S
Site 5
S49
P
S
V
E
T
L
D
S
P
T
G
S
H
V
E
Site 6
T51
V
E
T
L
D
S
P
T
G
S
H
V
E
W
C
Site 7
S53
T
L
D
S
P
T
G
S
H
V
E
W
C
K
Q
Site 8
S71
A
T
I
S
S
Q
I
S
G
S
V
T
S
E
N
Site 9
S73
I
S
S
Q
I
S
G
S
V
T
S
E
N
V
S
Site 10
T75
S
Q
I
S
G
S
V
T
S
E
N
V
S
R
D
Site 11
S76
Q
I
S
G
S
V
T
S
E
N
V
S
R
D
Y
Site 12
S80
S
V
T
S
E
N
V
S
R
D
Y
K
A
L
R
Site 13
Y83
S
E
N
V
S
R
D
Y
K
A
L
R
D
G
N
Site 14
Y135
T
V
T
D
F
K
L
Y
F
K
N
V
E
R
D
Site 15
S169
A
Q
S
H
G
D
N
S
C
G
I
E
I
V
C
Site 16
Y186
M
R
N
L
R
L
A
Y
K
Q
E
E
Q
S
K
Site 17
S208
N
K
H
A
F
P
L
S
N
G
Q
A
L
F
A
Site 18
Y218
Q
A
L
F
A
F
S
Y
K
E
K
F
P
I
N
Site 19
Y230
P
I
N
G
W
K
V
Y
D
P
V
S
E
Y
K
Site 20
S234
W
K
V
Y
D
P
V
S
E
Y
K
R
Q
G
L
Site 21
Y236
V
Y
D
P
V
S
E
Y
K
R
Q
G
L
P
N
Site 22
S245
R
Q
G
L
P
N
E
S
W
K
I
S
K
I
N
Site 23
S277
S
V
K
D
D
D
L
S
K
V
A
A
F
R
A
Site 24
S292
K
G
R
V
P
V
L
S
W
I
H
P
E
S
Q
Site 25
T301
I
H
P
E
S
Q
A
T
I
T
R
C
S
Q
P
Site 26
T303
P
E
S
Q
A
T
I
T
R
C
S
Q
P
L
V
Site 27
S306
Q
A
T
I
T
R
C
S
Q
P
L
V
G
P
N
Site 28
Y323
R
C
K
E
D
E
K
Y
L
Q
T
I
M
D
A
Site 29
S346
I
F
D
A
R
Q
N
S
V
A
D
T
N
K
T
Site 30
T350
R
Q
N
S
V
A
D
T
N
K
T
K
G
G
G
Site 31
Y358
N
K
T
K
G
G
G
Y
E
S
E
S
A
Y
P
Site 32
S360
T
K
G
G
G
Y
E
S
E
S
A
Y
P
N
A
Site 33
S362
G
G
G
Y
E
S
E
S
A
Y
P
N
A
E
L
Site 34
Y364
G
Y
E
S
E
S
A
Y
P
N
A
E
L
V
F
Site 35
S383
N
I
H
V
M
R
E
S
L
R
K
L
K
E
I
Site 36
Y392
R
K
L
K
E
I
V
Y
P
S
I
D
E
A
R
Site 37
S394
L
K
E
I
V
Y
P
S
I
D
E
A
R
W
L
Site 38
S429
R
I
A
D
K
I
E
S
G
K
T
S
V
V
V
Site 39
T432
D
K
I
E
S
G
K
T
S
V
V
V
H
C
S
Site 40
S433
K
I
E
S
G
K
T
S
V
V
V
H
C
S
D
Site 41
T445
C
S
D
G
W
D
R
T
A
Q
L
T
S
L
A
Site 42
Y460
M
L
M
L
D
S
Y
Y
R
T
I
K
G
F
E
Site 43
T462
M
L
D
S
Y
Y
R
T
I
K
G
F
E
T
L
Site 44
T468
R
T
I
K
G
F
E
T
L
V
E
K
E
W
I
Site 45
S498
N
H
A
D
A
D
R
S
P
I
F
L
Q
F
V
Site 46
Y555
Q
R
F
K
E
D
V
Y
T
K
T
I
S
L
W
Site 47
T556
R
F
K
E
D
V
Y
T
K
T
I
S
L
W
S
Site 48
T558
K
E
D
V
Y
T
K
T
I
S
L
W
S
Y
I
Site 49
S563
T
K
T
I
S
L
W
S
Y
I
N
S
Q
L
D
Site 50
Y564
K
T
I
S
L
W
S
Y
I
N
S
Q
L
D
E
Site 51
S567
S
L
W
S
Y
I
N
S
Q
L
D
E
F
S
N
Site 52
Y580
S
N
P
F
F
V
N
Y
E
N
H
V
L
Y
P
Site 53
Y586
N
Y
E
N
H
V
L
Y
P
V
A
S
L
S
H
Site 54
Y600
H
L
E
L
W
V
N
Y
Y
V
R
W
N
P
R
Site 55
T641
G
L
Q
R
E
V
A
T
R
A
V
S
S
S
S
Site 56
S645
E
V
A
T
R
A
V
S
S
S
S
E
R
G
S
Site 57
S646
V
A
T
R
A
V
S
S
S
S
E
R
G
S
S
Site 58
S647
A
T
R
A
V
S
S
S
S
E
R
G
S
S
P
Site 59
S648
T
R
A
V
S
S
S
S
E
R
G
S
S
P
S
Site 60
S652
S
S
S
S
E
R
G
S
S
P
S
H
S
A
T
Site 61
S653
S
S
S
E
R
G
S
S
P
S
H
S
A
T
S
Site 62
S655
S
E
R
G
S
S
P
S
H
S
A
T
S
V
H
Site 63
S657
R
G
S
S
P
S
H
S
A
T
S
V
H
T
S
Site 64
T659
S
S
P
S
H
S
A
T
S
V
H
T
S
V
_
Site 65
S660
S
P
S
H
S
A
T
S
V
H
T
S
V
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation