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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LAMC2
Full Name:
Laminin subunit gamma-2
Alias:
B2T; BM600; BM600-100kDa; cell-scattering factor 140 kDa subunit; CSF 140 kDa subunit; EBR2; EBR2A; kalinin/nicein/epiligrin 100 kDa subunit; ladsin 140 kDa subunit; LAMB2T; laminin 5 gamma 2; LAMNB2
Type:
Extracellular matrix
Mass (Da):
130976
Number AA:
1193
UniProt ID:
Q13753
International Prot ID:
IPI00015117
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005604
Uniprot
OncoNet
Molecular Function:
GO:0008201
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
GO:0008544
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T22
L
L
P
A
A
R
A
T
S
R
R
E
V
C
D
Site 2
S23
L
P
A
A
R
A
T
S
R
R
E
V
C
D
C
Site 3
T47
D
R
E
L
H
R
Q
T
G
N
G
F
R
C
L
Site 4
S88
C
L
P
C
N
C
N
S
K
G
S
L
S
A
R
Site 5
S91
C
N
C
N
S
K
G
S
L
S
A
R
C
D
N
Site 6
S93
C
N
S
K
G
S
L
S
A
R
C
D
N
S
G
Site 7
S99
L
S
A
R
C
D
N
S
G
R
C
S
C
K
P
Site 8
S103
C
D
N
S
G
R
C
S
C
K
P
G
V
T
G
Site 9
T124
L
P
G
F
H
M
L
T
D
A
G
C
T
Q
D
Site 10
S137
Q
D
Q
R
L
L
D
S
K
C
D
C
D
P
A
Site 11
Y173
C
D
R
C
R
S
G
Y
Y
N
L
D
G
G
N
Site 12
Y174
D
R
C
R
S
G
Y
Y
N
L
D
G
G
N
P
Site 13
S195
F
C
Y
G
H
S
A
S
C
R
S
S
A
E
Y
Site 14
S198
G
H
S
A
S
C
R
S
S
A
E
Y
S
V
H
Site 15
S199
H
S
A
S
C
R
S
S
A
E
Y
S
V
H
K
Site 16
Y202
S
C
R
S
S
A
E
Y
S
V
H
K
I
T
S
Site 17
S203
C
R
S
S
A
E
Y
S
V
H
K
I
T
S
T
Site 18
T210
S
V
H
K
I
T
S
T
F
H
Q
D
V
D
G
Site 19
S226
K
A
V
Q
R
N
G
S
P
A
K
L
Q
W
S
Site 20
S233
S
P
A
K
L
Q
W
S
Q
R
H
Q
D
V
F
Site 21
S241
Q
R
H
Q
D
V
F
S
S
A
Q
R
L
D
P
Site 22
Y250
A
Q
R
L
D
P
V
Y
F
V
A
P
A
K
F
Site 23
S264
F
L
G
N
Q
Q
V
S
Y
G
Q
S
L
S
F
Site 24
Y265
L
G
N
Q
Q
V
S
Y
G
Q
S
L
S
F
D
Site 25
S268
Q
Q
V
S
Y
G
Q
S
L
S
F
D
Y
R
V
Site 26
S270
V
S
Y
G
Q
S
L
S
F
D
Y
R
V
D
R
Site 27
Y273
G
Q
S
L
S
F
D
Y
R
V
D
R
G
G
R
Site 28
S283
D
R
G
G
R
H
P
S
A
H
D
V
I
L
E
Site 29
T314
L
P
C
G
L
T
K
T
Y
T
F
R
L
N
E
Site 30
T316
C
G
L
T
K
T
Y
T
F
R
L
N
E
H
P
Site 31
S324
F
R
L
N
E
H
P
S
N
N
W
S
P
Q
L
Site 32
S328
E
H
P
S
N
N
W
S
P
Q
L
S
Y
F
E
Site 33
S332
N
N
W
S
P
Q
L
S
Y
F
E
Y
R
R
L
Site 34
Y333
N
W
S
P
Q
L
S
Y
F
E
Y
R
R
L
L
Site 35
Y336
P
Q
L
S
Y
F
E
Y
R
R
L
L
R
N
L
Site 36
T344
R
R
L
L
R
N
L
T
A
L
R
I
R
A
T
Site 37
T351
T
A
L
R
I
R
A
T
Y
G
E
Y
S
T
G
Site 38
Y352
A
L
R
I
R
A
T
Y
G
E
Y
S
T
G
Y
Site 39
S356
R
A
T
Y
G
E
Y
S
T
G
Y
I
D
N
V
Site 40
Y359
Y
G
E
Y
S
T
G
Y
I
D
N
V
T
L
I
Site 41
Y400
C
Q
D
C
A
S
G
Y
K
R
D
S
A
R
L
Site 42
S404
A
S
G
Y
K
R
D
S
A
R
L
G
P
F
G
Site 43
T428
G
G
A
C
D
P
D
T
G
D
C
Y
S
G
D
Site 44
Y432
D
P
D
T
G
D
C
Y
S
G
D
E
N
P
D
Site 45
S433
P
D
T
G
D
C
Y
S
G
D
E
N
P
D
I
Site 46
Y450
A
D
C
P
I
G
F
Y
N
D
P
H
D
P
R
Site 47
T476
S
C
S
V
M
P
E
T
E
E
V
V
C
N
N
Site 48
Y500
C
E
L
C
A
D
G
Y
F
G
D
P
F
G
E
Site 49
T535
S
G
N
C
D
R
L
T
G
R
C
L
K
C
I
Site 50
S587
S
E
P
V
G
C
R
S
D
G
T
C
V
C
K
Site 51
S635
Q
R
M
E
A
L
I
S
K
A
Q
G
G
D
G
Site 52
T647
G
D
G
V
V
P
D
T
E
L
E
G
R
M
Q
Site 53
S670
I
L
R
D
A
Q
I
S
E
G
A
S
R
S
L
Site 54
S674
A
Q
I
S
E
G
A
S
R
S
L
G
L
Q
L
Site 55
S676
I
S
E
G
A
S
R
S
L
G
L
Q
L
A
K
Site 56
S686
L
Q
L
A
K
V
R
S
Q
E
N
S
Y
Q
S
Site 57
S690
K
V
R
S
Q
E
N
S
Y
Q
S
R
L
D
D
Site 58
T701
R
L
D
D
L
K
M
T
V
E
R
V
R
A
L
Site 59
S710
E
R
V
R
A
L
G
S
Q
Y
Q
N
R
V
R
Site 60
T719
Y
Q
N
R
V
R
D
T
H
R
L
I
T
Q
M
Site 61
T724
R
D
T
H
R
L
I
T
Q
M
Q
L
S
L
A
Site 62
S733
M
Q
L
S
L
A
E
S
E
A
S
L
G
N
T
Site 63
S736
S
L
A
E
S
E
A
S
L
G
N
T
N
I
P
Site 64
T740
S
E
A
S
L
G
N
T
N
I
P
A
S
D
H
Site 65
S745
G
N
T
N
I
P
A
S
D
H
Y
V
G
P
N
Site 66
Y748
N
I
P
A
S
D
H
Y
V
G
P
N
G
F
K
Site 67
S756
V
G
P
N
G
F
K
S
L
A
Q
E
A
T
R
Site 68
S767
E
A
T
R
L
A
E
S
H
V
E
S
A
S
N
Site 69
S771
L
A
E
S
H
V
E
S
A
S
N
M
E
Q
L
Site 70
S773
E
S
H
V
E
S
A
S
N
M
E
Q
L
T
R
Site 71
T782
M
E
Q
L
T
R
E
T
E
D
Y
S
K
Q
A
Site 72
Y785
L
T
R
E
T
E
D
Y
S
K
Q
A
L
S
L
Site 73
S786
T
R
E
T
E
D
Y
S
K
Q
A
L
S
L
V
Site 74
S791
D
Y
S
K
Q
A
L
S
L
V
R
K
A
L
H
Site 75
S803
A
L
H
E
G
V
G
S
G
S
G
S
P
D
G
Site 76
S805
H
E
G
V
G
S
G
S
G
S
P
D
G
A
V
Site 77
S807
G
V
G
S
G
S
G
S
P
D
G
A
V
V
Q
Site 78
S825
E
K
L
E
K
T
K
S
L
A
Q
Q
L
T
R
Site 79
T835
Q
Q
L
T
R
E
A
T
Q
A
E
I
E
A
D
Site 80
S844
A
E
I
E
A
D
R
S
Y
Q
H
S
L
R
L
Site 81
Y845
E
I
E
A
D
R
S
Y
Q
H
S
L
R
L
L
Site 82
S848
A
D
R
S
Y
Q
H
S
L
R
L
L
D
S
V
Site 83
S854
H
S
L
R
L
L
D
S
V
S
R
L
Q
G
V
Site 84
S856
L
R
L
L
D
S
V
S
R
L
Q
G
V
S
D
Site 85
S862
V
S
R
L
Q
G
V
S
D
Q
S
F
Q
V
E
Site 86
S865
L
Q
G
V
S
D
Q
S
F
Q
V
E
E
A
K
Site 87
S880
R
I
K
Q
K
A
D
S
L
S
S
L
V
T
R
Site 88
S882
K
Q
K
A
D
S
L
S
S
L
V
T
R
H
M
Site 89
S915
Q
L
L
Q
N
G
K
S
G
R
E
K
S
D
Q
Site 90
S920
G
K
S
G
R
E
K
S
D
Q
L
L
S
R
A
Site 91
S925
E
K
S
D
Q
L
L
S
R
A
N
L
A
K
S
Site 92
S932
S
R
A
N
L
A
K
S
R
A
Q
E
A
L
S
Site 93
S939
S
R
A
Q
E
A
L
S
M
G
N
A
T
F
Y
Site 94
Y946
S
M
G
N
A
T
F
Y
E
V
E
S
I
L
K
Site 95
S977
E
E
A
M
K
R
L
S
Y
I
S
Q
K
V
S
Site 96
Y978
E
A
M
K
R
L
S
Y
I
S
Q
K
V
S
D
Site 97
S980
M
K
R
L
S
Y
I
S
Q
K
V
S
D
A
S
Site 98
S984
S
Y
I
S
Q
K
V
S
D
A
S
D
K
T
Q
Site 99
S987
S
Q
K
V
S
D
A
S
D
K
T
Q
Q
A
E
Site 100
T990
V
S
D
A
S
D
K
T
Q
Q
A
E
R
A
L
Site 101
S1018
A
G
E
A
L
E
I
S
S
E
I
E
Q
E
I
Site 102
S1048
A
M
E
K
G
L
A
S
L
K
S
E
M
R
E
Site 103
S1051
K
G
L
A
S
L
K
S
E
M
R
E
V
E
G
Site 104
T1069
R
K
E
L
E
F
D
T
N
M
D
A
V
Q
M
Site 105
S1114
H
L
M
D
Q
P
L
S
V
D
E
E
G
L
V
Site 106
S1128
V
L
L
E
Q
K
L
S
R
A
K
T
Q
I
N
Site 107
T1132
Q
K
L
S
R
A
K
T
Q
I
N
S
Q
L
R
Site 108
S1136
R
A
K
T
Q
I
N
S
Q
L
R
P
M
M
S
Site 109
S1143
S
Q
L
R
P
M
M
S
E
L
E
E
R
A
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation