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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EXOSC2
Full Name:
Exosome complex exonuclease RRP4
Alias:
EXOS2; Exosome component 2; HRrp4p; P7; Ribosomal RNA processing protein 4; Ribosomal RNA-processing protein 4; RRP4; Rrp4p
Type:
RNA processing; EC 3.1.13.-; Ribonuclease
Mass (Da):
32789
Number AA:
293
UniProt ID:
Q13868
International Prot ID:
IPI00015905
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0000178
GO:0005730
Uniprot
OncoNet
Molecular Function:
GO:0000175
GO:0008312
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006364
GO:0006364
GO:0006396
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
P
V
A
R
K
P
L
S
E
R
L
G
R
D
T
Site 2
T22
S
E
R
L
G
R
D
T
K
K
H
L
V
V
P
Site 3
T32
H
L
V
V
P
G
D
T
I
T
T
D
T
G
F
Site 4
T37
G
D
T
I
T
T
D
T
G
F
M
R
G
H
G
Site 5
T45
G
F
M
R
G
H
G
T
Y
M
G
E
E
K
L
Site 6
Y46
F
M
R
G
H
G
T
Y
M
G
E
E
K
L
I
Site 7
S55
G
E
E
K
L
I
A
S
V
A
G
S
V
E
R
Site 8
T89
D
I
V
V
G
R
I
T
E
V
Q
Q
K
R
W
Site 9
T100
Q
K
R
W
K
V
E
T
N
S
R
L
D
S
V
Site 10
S102
R
W
K
V
E
T
N
S
R
L
D
S
V
L
L
Site 11
S106
E
T
N
S
R
L
D
S
V
L
L
L
S
S
M
Site 12
S124
G
G
E
L
R
R
R
S
A
E
D
E
L
A
M
Site 13
S155
V
F
S
D
G
A
V
S
L
H
T
R
S
L
K
Site 14
S160
A
V
S
L
H
T
R
S
L
K
Y
G
K
L
G
Site 15
S175
Q
G
V
L
V
Q
V
S
P
S
L
V
K
R
Q
Site 16
T184
S
L
V
K
R
Q
K
T
H
F
H
D
L
P
C
Site 17
Y206
N
N
G
F
I
W
I
Y
P
T
P
E
H
K
E
Site 18
T208
G
F
I
W
I
Y
P
T
P
E
H
K
E
E
E
Site 19
Y260
D
T
S
I
L
Y
C
Y
E
A
S
L
P
H
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation