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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KLF5
Full Name:
Krueppel-like factor 5
Alias:
Basic transcription element binding protein 2; BTEB2; BTE-binding protein 2; CKLF; Colon krueppel-like factor; GC box binding protein 2; IKLF; Intestinal-enriched krueppel-like factor; Kruppel-like factor 5 (intestinal)
Type:
Transcription factor
Mass (Da):
50792
Number AA:
457
UniProt ID:
Q13887
International Prot ID:
IPI00015934
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003702
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006366
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T76
Q
P
A
Q
P
P
A
T
G
P
R
L
P
P
E
Site 2
Y95
T
R
C
E
M
E
K
Y
L
T
P
Q
L
P
P
Site 3
T97
C
E
M
E
K
Y
L
T
P
Q
L
P
P
V
P
Site 4
Y112
I
I
P
E
H
K
K
Y
R
R
D
S
A
S
V
Site 5
S116
H
K
K
Y
R
R
D
S
A
S
V
V
D
Q
F
Site 6
S118
K
Y
R
R
D
S
A
S
V
V
D
Q
F
F
T
Site 7
T125
S
V
V
D
Q
F
F
T
D
T
E
G
L
P
Y
Site 8
T127
V
D
Q
F
F
T
D
T
E
G
L
P
Y
S
I
Site 9
Y132
T
D
T
E
G
L
P
Y
S
I
N
M
N
V
F
Site 10
Y151
T
H
L
R
T
G
L
Y
K
S
Q
R
P
C
V
Site 11
S153
L
R
T
G
L
Y
K
S
Q
R
P
C
V
T
H
Site 12
S170
T
E
P
V
A
I
F
S
H
Q
S
E
T
T
A
Site 13
T175
I
F
S
H
Q
S
E
T
T
A
P
P
P
A
P
Site 14
T190
T
Q
A
L
P
E
F
T
S
I
F
S
S
H
Q
Site 15
S191
Q
A
L
P
E
F
T
S
I
F
S
S
H
Q
T
Site 16
S195
E
F
T
S
I
F
S
S
H
Q
T
A
A
P
E
Site 17
T198
S
I
F
S
S
H
Q
T
A
A
P
E
V
N
N
Site 18
T214
F
I
K
Q
E
L
P
T
P
D
L
H
L
S
V
Site 19
S220
P
T
P
D
L
H
L
S
V
P
T
Q
Q
G
H
Site 20
Y229
P
T
Q
Q
G
H
L
Y
Q
L
L
N
T
P
D
Site 21
T234
H
L
Y
Q
L
L
N
T
P
D
L
D
M
P
S
Site 22
S241
T
P
D
L
D
M
P
S
S
T
N
Q
T
A
A
Site 23
S242
P
D
L
D
M
P
S
S
T
N
Q
T
A
A
M
Site 24
T251
N
Q
T
A
A
M
D
T
L
N
V
S
M
S
A
Site 25
Y286
Q
G
M
P
P
C
T
Y
T
M
P
S
Q
F
L
Site 26
T287
G
M
P
P
C
T
Y
T
M
P
S
Q
F
L
P
Site 27
T298
Q
F
L
P
Q
Q
A
T
Y
F
P
P
S
P
P
Site 28
Y299
F
L
P
Q
Q
A
T
Y
F
P
P
S
P
P
S
Site 29
S303
Q
A
T
Y
F
P
P
S
P
P
S
S
E
P
G
Site 30
S306
Y
F
P
P
S
P
P
S
S
E
P
G
S
P
D
Site 31
S307
F
P
P
S
P
P
S
S
E
P
G
S
P
D
R
Site 32
S311
P
P
S
S
E
P
G
S
P
D
R
Q
A
E
M
Site 33
T323
A
E
M
L
Q
N
L
T
P
P
P
S
Y
A
A
Site 34
S327
Q
N
L
T
P
P
P
S
Y
A
A
T
I
A
S
Site 35
Y328
N
L
T
P
P
P
S
Y
A
A
T
I
A
S
K
Site 36
T346
H
N
P
N
L
P
T
T
L
P
V
N
S
Q
N
Site 37
S351
P
T
T
L
P
V
N
S
Q
N
I
Q
P
V
R
Site 38
Y359
Q
N
I
Q
P
V
R
Y
N
R
R
S
N
P
D
Site 39
S363
P
V
R
Y
N
R
R
S
N
P
D
L
E
K
R
Site 40
Y374
L
E
K
R
R
I
H
Y
C
D
Y
P
G
C
T
Site 41
Y377
R
R
I
H
Y
C
D
Y
P
G
C
T
K
V
Y
Site 42
Y384
Y
P
G
C
T
K
V
Y
T
K
S
S
H
L
K
Site 43
T385
P
G
C
T
K
V
Y
T
K
S
S
H
L
K
A
Site 44
S387
C
T
K
V
Y
T
K
S
S
H
L
K
A
H
L
Site 45
T396
H
L
K
A
H
L
R
T
H
T
G
E
K
P
Y
Site 46
T398
K
A
H
L
R
T
H
T
G
E
K
P
Y
K
C
Site 47
T421
F
A
R
S
D
E
L
T
R
H
Y
R
K
H
T
Site 48
Y424
S
D
E
L
T
R
H
Y
R
K
H
T
G
A
K
Site 49
T428
T
R
H
Y
R
K
H
T
G
A
K
P
F
Q
C
Site 50
S441
Q
C
G
V
C
N
R
S
F
S
R
S
D
H
L
Site 51
S443
G
V
C
N
R
S
F
S
R
S
D
H
L
A
L
Site 52
S445
C
N
R
S
F
S
R
S
D
H
L
A
L
H
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation