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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCIN
Full Name:
Calicin
Alias:
Type:
Mass (Da):
66582
Number AA:
588
UniProt ID:
Q13939
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y10
L
E
F
T
E
K
N
Y
N
S
F
V
L
Q
N
Site 2
Y27
R
Q
R
K
R
K
E
Y
W
D
M
A
L
S
V
Site 3
S59
L
V
R
S
L
I
S
S
N
D
M
K
T
A
D
Site 4
T64
I
S
S
N
D
M
K
T
A
D
E
L
F
I
T
Site 5
T81
T
S
Y
L
S
P
V
T
V
D
Q
L
L
D
Y
Site 6
Y110
E
L
L
R
G
A
Q
Y
F
N
T
P
R
L
R
Site 7
T113
R
G
A
Q
Y
F
N
T
P
R
L
R
V
H
C
Site 8
Y153
K
E
V
S
D
V
A
Y
S
G
I
R
D
N
F
Site 9
Y162
G
I
R
D
N
F
H
Y
W
A
S
P
E
G
S
Site 10
Y206
S
A
L
I
N
W
V
Y
F
R
K
E
D
R
E
Site 11
Y215
R
K
E
D
R
E
K
Y
F
K
K
F
F
N
Y
Site 12
Y222
Y
F
K
K
F
F
N
Y
I
N
L
N
A
V
S
Site 13
T232
L
N
A
V
S
N
K
T
L
V
F
A
S
N
K
Site 14
S248
V
G
M
E
N
T
S
S
H
T
T
L
I
E
S
Site 15
T251
E
N
T
S
S
H
T
T
L
I
E
S
V
L
M
Site 16
S255
S
H
T
T
L
I
E
S
V
L
M
D
R
K
Q
Site 17
S267
R
K
Q
E
R
P
C
S
L
L
V
Y
Q
R
K
Site 18
S321
P
Y
R
A
A
A
L
S
A
T
S
A
G
R
Y
Site 19
Y328
S
A
T
S
A
G
R
Y
I
Y
I
S
G
G
T
Site 20
Y330
T
S
A
G
R
Y
I
Y
I
S
G
G
T
T
E
Site 21
S332
A
G
R
Y
I
Y
I
S
G
G
T
T
E
Q
I
Site 22
T336
I
Y
I
S
G
G
T
T
E
Q
I
S
G
L
K
Site 23
S340
G
G
T
T
E
Q
I
S
G
L
K
T
A
W
R
Site 24
S354
R
Y
D
M
D
D
N
S
W
T
K
L
P
D
L
Site 25
T356
D
M
D
D
N
S
W
T
K
L
P
D
L
P
I
Site 26
Y389
G
S
I
A
P
R
R
Y
V
S
N
I
Y
R
Y
Site 27
S391
I
A
P
R
R
Y
V
S
N
I
Y
R
Y
D
E
Site 28
Y396
Y
V
S
N
I
Y
R
Y
D
E
R
K
E
V
W
Site 29
Y427
T
K
G
D
R
H
L
Y
I
V
T
G
R
C
L
Site 30
S472
F
N
H
R
P
L
L
S
F
Q
Q
D
N
I
L
Site 31
S487
C
V
H
S
H
R
Q
S
V
E
I
N
L
Q
K
Site 32
T500
Q
K
V
K
A
S
K
T
T
T
S
V
P
V
L
Site 33
T502
V
K
A
S
K
T
T
T
S
V
P
V
L
P
N
Site 34
S503
K
A
S
K
T
T
T
S
V
P
V
L
P
N
S
Site 35
S537
C
G
G
V
T
T
A
S
D
V
Q
T
K
D
Y
Site 36
T541
T
T
A
S
D
V
Q
T
K
D
Y
T
I
N
P
Site 37
Y544
S
D
V
Q
T
K
D
Y
T
I
N
P
N
A
F
Site 38
T545
D
V
Q
T
K
D
Y
T
I
N
P
N
A
F
L
Site 39
T557
A
F
L
L
D
Q
K
T
G
K
W
K
T
L
A
Site 40
T562
Q
K
T
G
K
W
K
T
L
A
P
P
P
E
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation