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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CIRBP
Full Name:
Cold-inducible RNA-binding protein
Alias:
A18 hnRNP; A18HNRNP; CIRP; Cold inducible RNA binding protein; Glycine-rich RNA binding protein; Glycine-rich RNA-binding protein CIRP
Type:
RNA binding protein
Mass (Da):
18648
Number AA:
172
UniProt ID:
Q14011
International Prot ID:
IPI00180954
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005654
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0000166
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0009409
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
K
L
F
V
G
G
L
S
F
D
T
N
E
Q
S
Site 2
T17
V
G
G
L
S
F
D
T
N
E
Q
S
L
E
Q
Site 3
S21
S
F
D
T
N
E
Q
S
L
E
Q
V
F
S
K
Site 4
S27
Q
S
L
E
Q
V
F
S
K
Y
G
Q
I
S
E
Site 5
S33
F
S
K
Y
G
Q
I
S
E
V
V
V
V
K
D
Site 6
T43
V
V
V
K
D
R
E
T
Q
R
S
R
G
F
G
Site 7
S46
K
D
R
E
T
Q
R
S
R
G
F
G
F
V
T
Site 8
T53
S
R
G
F
G
F
V
T
F
E
N
I
D
D
A
Site 9
S71
M
M
A
M
N
G
K
S
V
D
G
R
Q
I
R
Site 10
S85
R
V
D
Q
A
G
K
S
S
D
N
R
S
R
G
Site 11
S86
V
D
Q
A
G
K
S
S
D
N
R
S
R
G
Y
Site 12
S90
G
K
S
S
D
N
R
S
R
G
Y
R
G
G
S
Site 13
Y93
S
D
N
R
S
R
G
Y
R
G
G
S
A
G
G
Site 14
S97
S
R
G
Y
R
G
G
S
A
G
G
R
G
F
F
Site 15
S115
R
G
R
G
R
G
F
S
R
G
G
G
D
R
G
Site 16
Y123
R
G
G
G
D
R
G
Y
G
G
N
R
F
E
S
Site 17
S130
Y
G
G
N
R
F
E
S
R
S
G
G
Y
G
G
Site 18
S132
G
N
R
F
E
S
R
S
G
G
Y
G
G
S
R
Site 19
Y135
F
E
S
R
S
G
G
Y
G
G
S
R
D
Y
Y
Site 20
S138
R
S
G
G
Y
G
G
S
R
D
Y
Y
S
S
R
Site 21
Y141
G
Y
G
G
S
R
D
Y
Y
S
S
R
S
Q
S
Site 22
Y142
Y
G
G
S
R
D
Y
Y
S
S
R
S
Q
S
G
Site 23
S143
G
G
S
R
D
Y
Y
S
S
R
S
Q
S
G
G
Site 24
S144
G
S
R
D
Y
Y
S
S
R
S
Q
S
G
G
Y
Site 25
S146
R
D
Y
Y
S
S
R
S
Q
S
G
G
Y
S
D
Site 26
S148
Y
Y
S
S
R
S
Q
S
G
G
Y
S
D
R
S
Site 27
Y151
S
R
S
Q
S
G
G
Y
S
D
R
S
S
G
G
Site 28
S152
R
S
Q
S
G
G
Y
S
D
R
S
S
G
G
S
Site 29
S155
S
G
G
Y
S
D
R
S
S
G
G
S
Y
R
D
Site 30
S156
G
G
Y
S
D
R
S
S
G
G
S
Y
R
D
S
Site 31
S159
S
D
R
S
S
G
G
S
Y
R
D
S
Y
D
S
Site 32
Y160
D
R
S
S
G
G
S
Y
R
D
S
Y
D
S
Y
Site 33
S163
S
G
G
S
Y
R
D
S
Y
D
S
Y
A
T
H
Site 34
Y164
G
G
S
Y
R
D
S
Y
D
S
Y
A
T
H
N
Site 35
S166
S
Y
R
D
S
Y
D
S
Y
A
T
H
N
E
_
Site 36
Y167
Y
R
D
S
Y
D
S
Y
A
T
H
N
E
_
_
Site 37
T169
D
S
Y
D
S
Y
A
T
H
N
E
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation