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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
COL4A6
Full Name:
Collagen alpha-6(IV) chain
Alias:
Collagen IV, alpha-6 polypeptide; Collagen of basement membrane, alpha-6; Collagen, type IV, alpha 6
Type:
Extracellular matrix protein
Mass (Da):
163807
Number AA:
1691
UniProt ID:
Q14031
International Prot ID:
IPI00028348
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005587
Uniprot
OncoNet
Molecular Function:
GO:0005201
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
GO:0030198
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S26
L
A
A
A
G
E
K
S
Y
G
K
P
C
G
G
Site 2
Y27
A
A
A
G
E
K
S
Y
G
K
P
C
G
G
Q
Site 3
T67
P
T
G
P
Q
G
F
T
G
S
T
G
L
S
G
Site 4
S69
G
P
Q
G
F
T
G
S
T
G
L
S
G
L
K
Site 5
S73
F
T
G
S
T
G
L
S
G
L
K
G
E
R
G
Site 6
Y141
G
F
P
G
P
D
G
Y
P
G
L
L
G
P
P
Site 7
S166
D
P
V
L
A
P
G
S
F
K
G
M
K
G
D
Site 8
S244
G
P
A
G
P
P
P
S
T
G
E
L
E
F
M
Site 9
T245
P
A
G
P
P
P
S
T
G
E
L
E
F
M
G
Site 10
S273
P
K
G
F
P
G
I
S
G
P
P
G
F
P
G
Site 11
T283
P
G
F
P
G
L
G
T
T
G
E
K
G
E
K
Site 12
S307
G
P
R
G
P
M
G
S
E
G
V
Q
G
P
P
Site 13
S358
D
I
D
G
A
V
I
S
G
N
P
G
D
P
G
Site 14
T419
Q
G
N
P
G
R
T
T
I
G
A
A
G
L
P
Site 15
S442
P
G
P
P
G
P
P
S
P
E
F
E
T
E
T
Site 16
T449
S
P
E
F
E
T
E
T
L
H
N
K
E
S
G
Site 17
S455
E
T
L
H
N
K
E
S
G
F
P
G
L
R
G
Site 18
S479
L
K
G
I
K
G
D
S
G
F
C
A
C
D
G
Site 19
T491
C
D
G
G
V
P
N
T
G
P
P
G
E
P
G
Site 20
S520
G
A
R
G
D
R
G
S
G
G
A
Q
G
P
A
Site 21
S539
L
V
G
P
L
G
P
S
G
P
K
G
K
K
G
Site 22
S551
K
K
G
E
P
I
L
S
T
I
Q
G
M
P
G
Site 23
T552
K
G
E
P
I
L
S
T
I
Q
G
M
P
G
D
Site 24
S563
M
P
G
D
R
G
D
S
G
S
Q
G
F
R
G
Site 25
S565
G
D
R
G
D
S
G
S
Q
G
F
R
G
V
I
Site 26
S650
G
Q
Q
G
L
P
G
S
K
G
I
T
L
P
C
Site 27
S666
I
P
G
S
Y
G
P
S
G
F
P
G
T
P
G
Site 28
T671
G
P
S
G
F
P
G
T
P
G
F
P
G
P
K
Site 29
T686
G
S
R
G
L
P
G
T
P
G
Q
P
G
S
S
Site 30
S692
G
T
P
G
Q
P
G
S
S
G
S
K
G
E
P
Site 31
S693
T
P
G
Q
P
G
S
S
G
S
K
G
E
P
G
Site 32
S695
G
Q
P
G
S
S
G
S
K
G
E
P
G
S
P
Site 33
S701
G
S
K
G
E
P
G
S
P
G
L
V
H
L
P
Site 34
S740
G
L
P
G
M
I
G
S
P
G
L
P
G
S
K
Site 35
S746
G
S
P
G
L
P
G
S
K
G
A
T
G
D
I
Site 36
T750
L
P
G
S
K
G
A
T
G
D
I
F
G
A
E
Site 37
S779
H
K
G
F
L
G
D
S
G
L
P
G
L
K
G
Site 38
S802
G
P
K
G
E
R
G
S
P
G
T
P
G
Q
V
Site 39
T805
G
E
R
G
S
P
G
T
P
G
Q
V
G
Q
P
Site 40
T814
G
Q
V
G
Q
P
G
T
P
G
S
S
G
P
Y
Site 41
S817
G
Q
P
G
T
P
G
S
S
G
P
Y
G
I
K
Site 42
Y821
T
P
G
S
S
G
P
Y
G
I
K
G
K
S
G
Site 43
S827
P
Y
G
I
K
G
K
S
G
L
P
G
A
P
G
Site 44
S839
A
P
G
F
P
G
I
S
G
H
P
G
K
K
G
Site 45
S856
G
K
K
G
P
P
G
S
I
V
K
K
G
L
P
Site 46
S883
G
L
K
G
S
P
G
S
P
G
V
A
G
L
P
Site 47
S893
V
A
G
L
P
A
L
S
G
P
K
G
E
K
G
Site 48
S901
G
P
K
G
E
K
G
S
V
G
F
V
G
F
P
Site 49
S928
G
L
K
G
I
P
G
S
T
G
K
M
G
P
S
Site 50
S935
S
T
G
K
M
G
P
S
G
R
A
G
T
P
G
Site 51
T940
G
P
S
G
R
A
G
T
P
G
E
K
G
D
R
Site 52
S957
P
G
P
V
G
I
P
S
P
R
R
P
M
S
N
Site 53
S963
P
S
P
R
R
P
M
S
N
L
W
L
K
G
D
Site 54
S973
W
L
K
G
D
K
G
S
Q
G
S
A
G
S
N
Site 55
S979
G
S
Q
G
S
A
G
S
N
G
F
P
G
P
R
Site 56
S1014
P
G
I
I
K
G
V
S
G
K
P
G
P
P
G
Site 57
T1038
L
K
G
S
S
G
I
T
G
F
P
G
M
P
G
Site 58
S1049
G
M
P
G
E
S
G
S
Q
G
I
R
G
S
P
Site 59
S1055
G
S
Q
G
I
R
G
S
P
G
L
P
G
A
S
Site 60
S1062
S
P
G
L
P
G
A
S
G
L
P
G
L
K
G
Site 61
T1074
L
K
G
D
N
G
Q
T
V
E
I
S
G
S
P
Site 62
S1078
N
G
Q
T
V
E
I
S
G
S
P
G
P
K
G
Site 63
S1080
Q
T
V
E
I
S
G
S
P
G
P
K
G
Q
P
Site 64
S1090
P
K
G
Q
P
G
E
S
G
F
K
G
T
K
G
Site 65
S1120
E
D
G
K
V
G
V
S
G
D
V
G
L
P
G
Site 66
S1146
G
E
P
G
L
P
G
S
S
G
H
Q
G
A
I
Site 67
T1188
G
T
K
G
T
H
G
T
P
G
P
S
I
T
G
Site 68
S1192
T
H
G
T
P
G
P
S
I
T
G
V
P
G
P
Site 69
T1194
G
T
P
G
P
S
I
T
G
V
P
G
P
A
G
Site 70
Y1211
G
P
K
G
E
K
G
Y
P
G
I
G
I
G
A
Site 71
S1286
P
G
P
P
G
P
S
S
N
Q
G
D
T
G
D
Site 72
T1291
P
S
S
N
Q
G
D
T
G
D
P
G
F
P
G
Site 73
S1315
D
Q
G
I
P
G
F
S
G
L
P
G
E
L
G
Site 74
T1335
G
E
P
G
F
M
G
T
P
G
K
V
G
P
P
Site 75
S1359
G
K
A
G
P
R
G
S
S
G
L
Q
G
D
P
Site 76
S1360
K
A
G
P
R
G
S
S
G
L
Q
G
D
P
G
Site 77
T1369
L
Q
G
D
P
G
Q
T
P
T
A
E
A
V
Q
Site 78
T1394
I
D
G
I
P
G
L
T
G
D
P
G
A
Q
G
Site 79
S1421
I
P
G
K
D
G
P
S
G
L
P
G
P
P
G
Site 80
Y1468
G
Q
S
M
R
V
G
Y
T
L
V
K
H
S
Q
Site 81
T1469
Q
S
M
R
V
G
Y
T
L
V
K
H
S
Q
S
Site 82
S1474
G
Y
T
L
V
K
H
S
Q
S
E
Q
V
P
P
Site 83
S1476
T
L
V
K
H
S
Q
S
E
Q
V
P
P
C
P
Site 84
S1514
Q
D
L
G
F
A
G
S
C
L
P
R
F
S
T
Site 85
Y1535
N
I
N
E
V
C
H
Y
A
R
R
N
D
K
S
Site 86
S1542
Y
A
R
R
N
D
K
S
Y
W
L
S
T
T
A
Site 87
Y1543
A
R
R
N
D
K
S
Y
W
L
S
T
T
A
P
Site 88
S1546
N
D
K
S
Y
W
L
S
T
T
A
P
I
P
M
Site 89
T1559
P
M
M
P
V
S
Q
T
Q
I
P
Q
Y
I
S
Site 90
Y1564
S
Q
T
Q
I
P
Q
Y
I
S
R
C
S
V
C
Site 91
S1569
P
Q
Y
I
S
R
C
S
V
C
E
A
P
S
Q
Site 92
S1582
S
Q
A
I
A
V
H
S
Q
D
I
T
I
P
Q
Site 93
S1617
G
A
E
G
G
G
Q
S
L
V
S
P
G
S
C
Site 94
S1620
G
G
G
Q
S
L
V
S
P
G
S
C
L
E
D
Site 95
S1623
Q
S
L
V
S
P
G
S
C
L
E
D
F
R
A
Site 96
Y1645
G
A
R
G
T
C
H
Y
F
A
N
K
Y
S
F
Site 97
T1655
N
K
Y
S
F
W
L
T
T
V
E
E
R
Q
Q
Site 98
T1656
K
Y
S
F
W
L
T
T
V
E
E
R
Q
Q
F
Site 99
S1669
Q
F
G
E
L
P
V
S
E
T
L
K
A
G
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation