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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BOP1
Full Name:
Ribosome biogenesis protein BOP1
Alias:
Block of proliferation 1; Block of proliferation 1 protein; KIAA0124
Type:
RNA binding protein
Mass (Da):
83630
Number AA:
746
UniProt ID:
Q14137
International Prot ID:
IPI00028955
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0070545
GO:0005654
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0008283
GO:0000463
GO:0051726
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
G
S
R
G
A
G
R
T
A
A
P
S
V
R
P
Site 2
S14
A
G
R
T
A
A
P
S
V
R
P
E
K
R
R
Site 3
S22
V
R
P
E
K
R
R
S
E
P
E
L
E
P
E
Site 4
T39
P
E
P
P
L
L
C
T
S
P
L
S
H
S
T
Site 5
S40
E
P
P
L
L
C
T
S
P
L
S
H
S
T
G
Site 6
S43
L
L
C
T
S
P
L
S
H
S
T
G
S
D
S
Site 7
S45
C
T
S
P
L
S
H
S
T
G
S
D
S
G
V
Site 8
T46
T
S
P
L
S
H
S
T
G
S
D
S
G
V
S
Site 9
S48
P
L
S
H
S
T
G
S
D
S
G
V
S
D
S
Site 10
S50
S
H
S
T
G
S
D
S
G
V
S
D
S
E
E
Site 11
S53
T
G
S
D
S
G
V
S
D
S
E
E
S
V
F
Site 12
S55
S
D
S
G
V
S
D
S
E
E
S
V
F
S
G
Site 13
S58
G
V
S
D
S
E
E
S
V
F
S
G
L
E
D
Site 14
S61
D
S
E
E
S
V
F
S
G
L
E
D
S
G
S
Site 15
S66
V
F
S
G
L
E
D
S
G
S
D
S
S
E
D
Site 16
S68
S
G
L
E
D
S
G
S
D
S
S
E
D
D
D
Site 17
S70
L
E
D
S
G
S
D
S
S
E
D
D
D
E
G
Site 18
S71
E
D
S
G
S
D
S
S
E
D
D
D
E
G
D
Site 19
T106
E
E
Q
V
Q
A
S
T
P
C
P
R
T
E
M
Site 20
T111
A
S
T
P
C
P
R
T
E
M
A
S
A
R
I
Site 21
S115
C
P
R
T
E
M
A
S
A
R
I
G
D
E
Y
Site 22
Y122
S
A
R
I
G
D
E
Y
A
E
D
S
S
D
E
Site 23
S126
G
D
E
Y
A
E
D
S
S
D
E
E
D
I
R
Site 24
S127
D
E
Y
A
E
D
S
S
D
E
E
D
I
R
N
Site 25
T135
D
E
E
D
I
R
N
T
V
G
N
V
P
L
E
Site 26
Y144
G
N
V
P
L
E
W
Y
D
D
F
P
H
V
G
Site 27
Y152
D
D
F
P
H
V
G
Y
D
L
D
G
R
R
I
Site 28
Y160
D
L
D
G
R
R
I
Y
K
P
L
R
T
R
D
Site 29
Y181
D
K
M
D
D
P
D
Y
W
R
T
V
Q
D
P
Site 30
T190
R
T
V
Q
D
P
M
T
G
R
D
L
R
L
T
Site 31
T197
T
G
R
D
L
R
L
T
D
E
Q
V
A
L
V
Site 32
S209
A
L
V
R
R
L
Q
S
G
Q
F
G
D
V
G
Site 33
Y220
G
D
V
G
F
N
P
Y
E
P
A
V
D
F
F
Site 34
T237
D
V
M
I
H
P
V
T
N
R
P
A
D
K
R
Site 35
S245
N
R
P
A
D
K
R
S
F
I
P
S
L
V
E
Site 36
S249
D
K
R
S
F
I
P
S
L
V
E
K
E
K
V
Site 37
T277
P
R
R
P
R
D
P
T
P
S
F
Y
D
L
W
Site 38
S279
R
P
R
D
P
T
P
S
F
Y
D
L
W
A
Q
Site 39
S313
A
L
P
G
H
A
E
S
Y
N
P
P
P
E
Y
Site 40
Y314
L
P
G
H
A
E
S
Y
N
P
P
P
E
Y
L
Site 41
Y320
S
Y
N
P
P
P
E
Y
L
L
S
E
E
E
R
Site 42
S323
P
P
P
E
Y
L
L
S
E
E
E
R
L
A
W
Site 43
S341
E
P
G
E
R
K
L
S
F
L
P
R
K
F
P
Site 44
S349
F
L
P
R
K
F
P
S
L
R
A
V
P
A
Y
Site 45
Y356
S
L
R
A
V
P
A
Y
G
R
F
I
Q
E
R
Site 46
Y371
F
E
R
C
L
D
L
Y
L
C
P
R
Q
R
K
Site 47
T403
R
D
L
Q
P
F
P
T
C
Q
A
L
V
Y
R
Site 48
Y409
P
T
C
Q
A
L
V
Y
R
G
H
S
D
L
V
Site 49
S420
S
D
L
V
R
C
L
S
V
S
P
G
G
Q
W
Site 50
S430
P
G
G
Q
W
L
V
S
G
S
D
D
G
S
L
Site 51
S432
G
Q
W
L
V
S
G
S
D
D
G
S
L
R
L
Site 52
S436
V
S
G
S
D
D
G
S
L
R
L
W
E
V
A
Site 53
S494
G
D
R
L
V
A
G
S
T
D
Q
L
L
S
A
Site 54
S500
G
S
T
D
Q
L
L
S
A
F
V
P
P
E
E
Site 55
S519
P
A
R
W
L
E
A
S
E
E
E
R
Q
V
G
Site 56
T541
G
K
P
V
T
Q
V
T
W
H
G
R
G
D
Y
Site 57
S567
Q
V
L
I
H
Q
L
S
R
R
R
S
Q
S
P
Site 58
S571
H
Q
L
S
R
R
R
S
Q
S
P
F
R
R
S
Site 59
S573
L
S
R
R
R
S
Q
S
P
F
R
R
S
H
G
Site 60
S578
S
Q
S
P
F
R
R
S
H
G
Q
V
Q
R
V
Site 61
Y605
S
Q
R
S
V
R
L
Y
H
L
L
R
Q
E
L
Site 62
T613
H
L
L
R
Q
E
L
T
K
K
L
M
P
N
C
Site 63
S625
P
N
C
K
W
V
S
S
L
A
V
H
P
A
G
Site 64
S642
V
I
C
G
S
Y
D
S
K
L
V
W
F
D
L
Site 65
Y656
L
D
L
S
T
K
P
Y
R
M
L
R
H
H
K
Site 66
S680
P
R
Y
P
L
F
A
S
G
S
D
D
G
S
V
Site 67
S736
T
Q
P
W
V
F
S
S
G
A
D
G
T
V
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation