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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SEPT6
Full Name:
Septin-6
Alias:
KIAA0128; SEP2; SEPT2; Septin 6
Type:
Mass (Da):
49717
Number AA:
434
UniProt ID:
Q14141
International Prot ID:
IPI00376992
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031105
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007049
GO:0000910
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S27
A
G
H
V
G
F
D
S
L
P
D
Q
L
V
N
Site 2
S36
P
D
Q
L
V
N
K
S
V
S
Q
G
F
C
F
Site 3
S56
G
E
T
G
L
G
K
S
T
L
M
D
T
L
F
Site 4
T57
E
T
G
L
G
K
S
T
L
M
D
T
L
F
N
Site 5
T61
G
K
S
T
L
M
D
T
L
F
N
T
K
F
E
Site 6
T75
E
G
E
P
A
T
H
T
Q
P
G
V
Q
L
Q
Site 7
Y86
V
Q
L
Q
S
N
T
Y
D
L
Q
E
S
N
V
Site 8
S114
D
Q
I
N
K
E
D
S
Y
K
P
I
V
E
F
Site 9
Y115
Q
I
N
K
E
D
S
Y
K
P
I
V
E
F
I
Site 10
T142
K
I
R
R
V
L
H
T
Y
H
D
S
R
I
H
Site 11
Y143
I
R
R
V
L
H
T
Y
H
D
S
R
I
H
V
Site 12
S146
V
L
H
T
Y
H
D
S
R
I
H
V
C
L
Y
Site 13
S164
P
T
G
H
S
L
K
S
L
D
L
V
T
M
K
Site 14
T169
L
K
S
L
D
L
V
T
M
K
K
L
D
S
K
Site 15
S192
K
A
D
A
I
S
K
S
E
L
T
K
F
K
I
Site 16
S207
K
I
T
S
E
L
V
S
N
G
V
Q
I
Y
Q
Site 17
Y213
V
S
N
G
V
Q
I
Y
Q
F
P
T
D
D
E
Site 18
S221
Q
F
P
T
D
D
E
S
V
A
E
I
N
G
T
Site 19
T290
M
E
D
L
R
E
Q
T
H
T
R
H
Y
E
L
Site 20
T292
D
L
R
E
Q
T
H
T
R
H
Y
E
L
Y
R
Site 21
Y295
E
Q
T
H
T
R
H
Y
E
L
Y
R
R
C
K
Site 22
Y298
H
T
R
H
Y
E
L
Y
R
R
C
K
L
E
E
Site 23
T311
E
E
M
G
F
K
D
T
D
P
D
S
K
P
F
Site 24
S315
F
K
D
T
D
P
D
S
K
P
F
S
L
Q
E
Site 25
S319
D
P
D
S
K
P
F
S
L
Q
E
T
Y
E
A
Site 26
T323
K
P
F
S
L
Q
E
T
Y
E
A
K
R
N
E
Site 27
Y324
P
F
S
L
Q
E
T
Y
E
A
K
R
N
E
F
Site 28
S388
K
L
E
D
K
K
K
S
L
D
D
E
V
N
A
Site 29
T401
N
A
F
K
Q
R
K
T
A
A
E
L
L
Q
S
Site 30
S408
T
A
A
E
L
L
Q
S
Q
G
S
Q
A
G
G
Site 31
S411
E
L
L
Q
S
Q
G
S
Q
A
G
G
S
Q
T
Site 32
S416
Q
G
S
Q
A
G
G
S
Q
T
L
K
R
D
K
Site 33
T418
S
Q
A
G
G
S
Q
T
L
K
R
D
K
E
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation