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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM53B
Full Name:
Protein FAM53B
Alias:
FA53B; KIAA0140; Loc9679
Type:
Mass (Da):
45768
Number AA:
422
UniProt ID:
Q14153
International Prot ID:
Isoform1 - IPI00029013
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T21
A
D
S
I
A
C
G
T
F
S
R
E
L
H
T
Site 2
S23
S
I
A
C
G
T
F
S
R
E
L
H
T
P
K
Site 3
T28
T
F
S
R
E
L
H
T
P
K
K
M
S
Q
G
Site 4
S33
L
H
T
P
K
K
M
S
Q
G
P
T
L
F
S
Site 5
T37
K
K
M
S
Q
G
P
T
L
F
S
C
G
I
M
Site 6
S64
P
L
Q
I
D
Q
P
S
T
S
I
W
E
C
L
Site 7
S66
Q
I
D
Q
P
S
T
S
I
W
E
C
L
P
E
Site 8
S76
E
C
L
P
E
K
D
S
S
L
W
H
R
E
A
Site 9
S77
C
L
P
E
K
D
S
S
L
W
H
R
E
A
V
Site 10
S97
T
S
L
I
K
D
L
S
I
S
D
H
N
G
N
Site 11
S99
L
I
K
D
L
S
I
S
D
H
N
G
N
P
S
Site 12
S106
S
D
H
N
G
N
P
S
A
P
P
S
K
R
Q
Site 13
S110
G
N
P
S
A
P
P
S
K
R
Q
C
R
S
L
Site 14
S116
P
S
K
R
Q
C
R
S
L
S
F
S
D
E
M
Site 15
S118
K
R
Q
C
R
S
L
S
F
S
D
E
M
S
S
Site 16
S120
Q
C
R
S
L
S
F
S
D
E
M
S
S
C
R
Site 17
S124
L
S
F
S
D
E
M
S
S
C
R
T
S
W
R
Site 18
S125
S
F
S
D
E
M
S
S
C
R
T
S
W
R
P
Site 19
T128
D
E
M
S
S
C
R
T
S
W
R
P
L
G
S
Site 20
S129
E
M
S
S
C
R
T
S
W
R
P
L
G
S
K
Site 21
S135
T
S
W
R
P
L
G
S
K
V
W
T
P
V
E
Site 22
T139
P
L
G
S
K
V
W
T
P
V
E
K
R
R
C
Site 23
Y147
P
V
E
K
R
R
C
Y
S
G
G
S
V
Q
R
Site 24
S148
V
E
K
R
R
C
Y
S
G
G
S
V
Q
R
Y
Site 25
S151
R
R
C
Y
S
G
G
S
V
Q
R
Y
S
N
G
Site 26
Y155
S
G
G
S
V
Q
R
Y
S
N
G
F
S
T
M
Site 27
S156
G
G
S
V
Q
R
Y
S
N
G
F
S
T
M
Q
Site 28
S160
Q
R
Y
S
N
G
F
S
T
M
Q
R
S
S
S
Site 29
T161
R
Y
S
N
G
F
S
T
M
Q
R
S
S
S
F
Site 30
S165
G
F
S
T
M
Q
R
S
S
S
F
S
L
P
S
Site 31
S166
F
S
T
M
Q
R
S
S
S
F
S
L
P
S
R
Site 32
S167
S
T
M
Q
R
S
S
S
F
S
L
P
S
R
A
Site 33
S169
M
Q
R
S
S
S
F
S
L
P
S
R
A
N
V
Site 34
S172
S
S
S
F
S
L
P
S
R
A
N
V
L
S
S
Site 35
S178
P
S
R
A
N
V
L
S
S
P
C
D
Q
A
G
Site 36
S179
S
R
A
N
V
L
S
S
P
C
D
Q
A
G
L
Site 37
S201
P
C
Q
G
V
P
G
S
A
P
C
G
Q
A
G
Site 38
T210
P
C
G
Q
A
G
D
T
W
S
P
D
L
H
P
Site 39
S212
G
Q
A
G
D
T
W
S
P
D
L
H
P
V
G
Site 40
S228
G
R
L
D
L
Q
R
S
L
S
C
S
H
E
Q
Site 41
S230
L
D
L
Q
R
S
L
S
C
S
H
E
Q
F
S
Site 42
S232
L
Q
R
S
L
S
C
S
H
E
Q
F
S
F
V
Site 43
Y241
E
Q
F
S
F
V
E
Y
C
P
P
S
A
N
S
Site 44
S245
F
V
E
Y
C
P
P
S
A
N
S
T
P
A
S
Site 45
S248
Y
C
P
P
S
A
N
S
T
P
A
S
T
P
E
Site 46
T249
C
P
P
S
A
N
S
T
P
A
S
T
P
E
L
Site 47
S252
S
A
N
S
T
P
A
S
T
P
E
L
A
R
R
Site 48
T253
A
N
S
T
P
A
S
T
P
E
L
A
R
R
S
Site 49
S260
T
P
E
L
A
R
R
S
S
G
L
S
R
S
R
Site 50
S261
P
E
L
A
R
R
S
S
G
L
S
R
S
R
S
Site 51
S264
A
R
R
S
S
G
L
S
R
S
R
S
Q
P
C
Site 52
S266
R
S
S
G
L
S
R
S
R
S
Q
P
C
V
L
Site 53
S268
S
G
L
S
R
S
R
S
Q
P
C
V
L
N
D
Site 54
S294
E
V
Q
E
Q
R
P
S
L
D
L
A
K
M
A
Site 55
T306
K
M
A
Q
N
C
Q
T
F
S
S
L
S
C
L
Site 56
S309
Q
N
C
Q
T
F
S
S
L
S
C
L
S
A
G
Site 57
S311
C
Q
T
F
S
S
L
S
C
L
S
A
G
T
E
Site 58
S324
T
E
D
C
G
P
Q
S
P
F
A
R
H
V
S
Site 59
S331
S
P
F
A
R
H
V
S
N
T
R
A
W
T
A
Site 60
T333
F
A
R
H
V
S
N
T
R
A
W
T
A
L
L
Site 61
S341
R
A
W
T
A
L
L
S
A
S
G
P
G
G
R
Site 62
T349
A
S
G
P
G
G
R
T
P
A
G
T
P
V
P
Site 63
T353
G
G
R
T
P
A
G
T
P
V
P
E
P
L
P
Site 64
S362
V
P
E
P
L
P
P
S
F
D
D
H
L
A
C
Site 65
S374
L
A
C
Q
E
D
L
S
C
E
E
S
D
S
C
Site 66
S378
E
D
L
S
C
E
E
S
D
S
C
A
L
D
E
Site 67
S380
L
S
C
E
E
S
D
S
C
A
L
D
E
D
C
Site 68
S406
D
R
G
A
P
G
N
S
L
C
S
L
D
G
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation