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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA0143
Full Name:
Protein EFR3 homolog A
Alias:
EFR3 A; EFR3A; EFR3-like; Protein EFR3 homolog A: Protein EFR3-like: Protein EFR3 homolog A: Protein EFR3-like: Protein EFR3 homolog A: Protein EFR3-like: Putative uncharacterized protein EFR3A
Type:
Unknown function
Mass (Da):
92924
Number AA:
821
UniProt ID:
Q14156
International Prot ID:
IPI00470711
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y16
C
S
A
L
R
P
R
Y
K
R
L
V
D
N
I
Site 2
T35
P
K
D
G
L
V
K
T
D
M
E
K
L
T
F
Site 3
T41
K
T
D
M
E
K
L
T
F
Y
A
V
S
A
P
Site 4
Y43
D
M
E
K
L
T
F
Y
A
V
S
A
P
E
K
Site 5
S46
K
L
T
F
Y
A
V
S
A
P
E
K
L
D
R
Site 6
S56
E
K
L
D
R
I
G
S
Y
L
A
E
R
L
S
Site 7
Y57
K
L
D
R
I
G
S
Y
L
A
E
R
L
S
R
Site 8
S63
S
Y
L
A
E
R
L
S
R
D
V
V
R
H
R
Site 9
T133
F
A
N
I
E
E
D
T
P
S
Y
H
R
R
Y
Site 10
Y136
I
E
E
D
T
P
S
Y
H
R
R
Y
D
F
F
Site 11
Y140
T
P
S
Y
H
R
R
Y
D
F
F
V
S
R
F
Site 12
S156
A
M
C
H
S
C
H
S
D
P
E
I
R
T
E
Site 13
T179
I
Q
G
V
V
R
K
T
V
N
D
E
L
R
A
Site 14
S213
Q
K
I
E
E
V
D
S
R
I
G
P
P
S
S
Site 15
S219
D
S
R
I
G
P
P
S
S
P
S
A
T
D
K
Site 16
S220
S
R
I
G
P
P
S
S
P
S
A
T
D
K
E
Site 17
S222
I
G
P
P
S
S
P
S
A
T
D
K
E
E
N
Site 18
T224
P
P
S
S
P
S
A
T
D
K
E
E
N
P
A
Site 19
T246
R
E
L
L
G
R
A
T
F
G
N
M
N
N
A
Site 20
S348
L
L
K
H
L
R
L
S
V
E
F
E
A
N
D
Site 21
S360
A
N
D
L
Q
G
G
S
V
G
S
V
N
L
N
Site 22
S363
L
Q
G
G
S
V
G
S
V
N
L
N
T
S
S
Site 23
S391
Q
T
I
G
F
F
G
S
N
L
P
D
Y
Q
R
Site 24
Y396
F
G
S
N
L
P
D
Y
Q
R
S
E
I
M
M
Site 25
S422
S
T
H
T
L
D
I
S
Q
L
G
D
L
G
T
Site 26
T429
S
Q
L
G
D
L
G
T
R
R
I
Q
I
M
L
Site 27
Y447
L
L
M
V
T
S
G
Y
K
A
K
T
I
V
T
Site 28
S466
S
F
L
D
P
L
L
S
P
S
L
M
E
D
Y
Site 29
S468
L
D
P
L
L
S
P
S
L
M
E
D
Y
E
L
Site 30
Y473
S
P
S
L
M
E
D
Y
E
L
R
Q
L
V
L
Site 31
T520
E
K
I
C
R
Q
D
T
S
F
M
K
K
N
G
Site 32
Y531
K
K
N
G
Q
Q
L
Y
R
H
I
Y
L
G
C
Site 33
Y535
Q
Q
L
Y
R
H
I
Y
L
G
C
K
E
E
D
Site 34
S650
D
K
C
M
L
P
K
S
L
E
K
H
E
K
D
Site 35
Y659
E
K
H
E
K
D
L
Y
F
L
T
N
K
I
A
Site 36
S668
L
T
N
K
I
A
E
S
L
G
G
S
G
Y
S
Site 37
S672
I
A
E
S
L
G
G
S
G
Y
S
V
E
R
L
Site 38
S675
S
L
G
G
S
G
Y
S
V
E
R
L
S
V
P
Site 39
S680
G
Y
S
V
E
R
L
S
V
P
Y
V
P
Q
V
Site 40
Y683
V
E
R
L
S
V
P
Y
V
P
Q
V
T
D
E
Site 41
T688
V
P
Y
V
P
Q
V
T
D
E
D
R
L
S
R
Site 42
S694
V
T
D
E
D
R
L
S
R
R
K
S
I
V
D
Site 43
S698
D
R
L
S
R
R
K
S
I
V
D
T
V
S
I
Site 44
T702
R
R
K
S
I
V
D
T
V
S
I
Q
V
D
I
Site 45
S711
S
I
Q
V
D
I
L
S
N
N
V
P
S
D
D
Site 46
S716
I
L
S
N
N
V
P
S
D
D
V
V
S
N
T
Site 47
S721
V
P
S
D
D
V
V
S
N
T
E
E
I
T
F
Site 48
S738
L
K
K
A
I
D
T
S
G
M
E
E
Q
E
K
Site 49
S769
E
I
A
A
Q
C
E
S
K
A
N
L
L
H
D
Site 50
S791
L
T
I
R
P
P
P
S
P
S
G
T
L
T
I
Site 51
S793
I
R
P
P
P
S
P
S
G
T
L
T
I
T
S
Site 52
T795
P
P
P
S
P
S
G
T
L
T
I
T
S
G
H
Site 53
T797
P
S
P
S
G
T
L
T
I
T
S
G
H
A
Q
Site 54
Y805
I
T
S
G
H
A
Q
Y
Q
S
V
P
V
Y
E
Site 55
S807
S
G
H
A
Q
Y
Q
S
V
P
V
Y
E
M
K
Site 56
Y811
Q
Y
Q
S
V
P
V
Y
E
M
K
F
P
D
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation