PhosphoNET

           
Protein Info 
   
Short Name:  DOC2A
Full Name:  Double C2-like domain-containing protein alpha
Alias:  Double C2-like domains, alpha
Type:  Membrane, Synapse, Cytoplasmic vesicle, Synaptosome, Cell junction, Synaptic vesicle protein
Mass (Da):  43959
Number AA:  400
UniProt ID:  Q14183
International Prot ID:  IPI00455076
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0030054  GO:0019898  GO:0005764 Uniprot OncoNet
Molecular Function:  GO:0005509  GO:0005544  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0007399  GO:0017158  GO:0007268 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S33IRPIRQISDYFPRGP
Site 2Y35PIRQISDYFPRGPGP
Site 3Y82DGAEVDSYDSDDATA
Site 4S84AEVDSYDSDDATALG
Site 5T88SYDSDDATALGTLEF
Site 6T147ANKLKTKTQRNTLNP
Site 7T151KTKTQRNTLNPVWNE
Site 8T161PVWNEDLTYSGITDD
Site 9Y162VWNEDLTYSGITDDD
Site 10T171GITDDDITHKVLRIA
Site 11S186VCDEDKLSHNEFIGE
Site 12S204PLRRLKPSQKKHFNI
Site 13S221ERQVPLASPSSMSAA
Site 14Y235ALRGISCYLKELEQA
Site 15S258ERGRILLSLSYSSRR
Site 16S260GRILLSLSYSSRRRG
Site 17Y261RILLSLSYSSRRRGL
Site 18Y286AAMDVNGYSDPYVKT
Site 19Y290VNGYSDPYVKTYLRP
Site 20T293YSDPYVKTYLRPDVD
Site 21Y294SDPYVKTYLRPDVDK
Site 22S303RPDVDKKSKHKTCVK
Site 23T307DKKSKHKTCVKKKTL
Site 24T313KTCVKKKTLNPEFNE
Site 25Y324EFNEEFFYEIELSTL
Site 26S329FFYEIELSTLATKTL
Site 27T333IELSTLATKTLEVTV
Site 28T339ATKTLEVTVWDYDIG
Site 29Y343LEVTVWDYDIGKSND
Site 30S356NDFIGGVSLGPGARG
Site 31S370GEARKHWSDCLQQPD
Site 32T385AALERWHTLTSELPP
Site 33T387LERWHTLTSELPPAA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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