KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
FHL2
Full Name:
Four and a half LIM domains protein 2
Alias:
DRAL; DRAL, SLIM3; FHL-2; Four and a half LIM domains 2; LIM-domain protein DRAL; Skeletal muscle LIM- protein 3; SLIM 3; SLIM3
Type:
Nuclear receptor co-regulator, Transcription, coactivator/corepressor
Mass (Da):
32193
Number AA:
279
UniProt ID:
Q14192
International Prot ID:
IPI00743342
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005856
GO:0005925
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0050681
GO:0042802
GO:0003713
PhosphoSite+
KinaseNET
Biological Process:
GO:0030521
GO:0045893
GO:0009725
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y19
E
S
L
F
G
K
K
Y
I
L
R
E
E
S
P
Site 2
S74
H
C
S
Q
C
R
N
S
L
V
D
K
P
F
A
Site 3
T90
K
E
D
Q
L
L
C
T
D
C
Y
S
N
E
Y
Site 4
Y93
Q
L
L
C
T
D
C
Y
S
N
E
Y
S
S
K
Site 5
Y97
T
D
C
Y
S
N
E
Y
S
S
K
C
Q
E
C
Site 6
T107
K
C
Q
E
C
K
K
T
I
M
P
G
T
R
K
Site 7
T112
K
K
T
I
M
P
G
T
R
K
M
E
Y
K
G
Site 8
Y117
P
G
T
R
K
M
E
Y
K
G
S
S
W
H
E
Site 9
T138
R
C
Q
Q
P
I
G
T
K
S
F
I
P
K
D
Site 10
S140
Q
Q
P
I
G
T
K
S
F
I
P
K
D
N
Q
Site 11
Y154
Q
N
F
C
V
P
C
Y
E
K
Q
H
A
M
Q
Site 12
T170
V
Q
C
K
K
P
I
T
T
G
G
V
T
Y
R
Site 13
T175
P
I
T
T
G
G
V
T
Y
R
E
Q
P
W
H
Site 14
Y176
I
T
T
G
G
V
T
Y
R
E
Q
P
W
H
K
Site 15
S196
T
A
C
R
K
Q
L
S
G
Q
R
F
T
A
R
Site 16
T201
Q
L
S
G
Q
R
F
T
A
R
D
D
F
A
Y
Site 17
T225
A
K
K
C
A
G
C
T
N
P
I
S
G
L
G
Site 18
S229
A
G
C
T
N
P
I
S
G
L
G
G
T
K
Y
Site 19
Y236
S
G
L
G
G
T
K
Y
I
S
F
E
E
R
Q
Site 20
S238
L
G
G
T
K
Y
I
S
F
E
E
R
Q
W
H
Site 21
S255
C
F
N
C
K
K
C
S
L
S
L
V
G
R
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation