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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ICT1
Full Name:
Peptidyl-tRNA hydrolase ICT1, mitochondrial
Alias:
Digestion substraction 1; DS1; DS-1; Immature colon carcinoma transcript 1
Type:
Unknown function
Mass (Da):
23630
Number AA:
206
UniProt ID:
Q14197
International Prot ID:
IPI00029114
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003747
PhosphoSite+
KinaseNET
Biological Process:
GO:0006415
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T37
L
H
K
Q
K
D
G
T
E
F
K
S
I
Y
S
Site 2
S41
K
D
G
T
E
F
K
S
I
Y
S
L
D
K
L
Site 3
Y43
G
T
E
F
K
S
I
Y
S
L
D
K
L
Y
P
Site 4
S44
T
E
F
K
S
I
Y
S
L
D
K
L
Y
P
E
Site 5
Y49
I
Y
S
L
D
K
L
Y
P
E
S
Q
G
S
D
Site 6
S52
L
D
K
L
Y
P
E
S
Q
G
S
D
T
A
W
Site 7
S55
L
Y
P
E
S
Q
G
S
D
T
A
W
R
V
P
Site 8
T57
P
E
S
Q
G
S
D
T
A
W
R
V
P
N
G
Site 9
S70
N
G
A
K
Q
A
D
S
D
I
P
L
D
R
L
Site 10
T78
D
I
P
L
D
R
L
T
I
S
Y
C
R
S
S
Site 11
S80
P
L
D
R
L
T
I
S
Y
C
R
S
S
G
P
Site 12
Y81
L
D
R
L
T
I
S
Y
C
R
S
S
G
P
G
Site 13
S84
L
T
I
S
Y
C
R
S
S
G
P
G
G
Q
N
Site 14
S85
T
I
S
Y
C
R
S
S
G
P
G
G
Q
N
V
Site 15
S97
Q
N
V
N
K
V
N
S
K
A
E
V
R
F
H
Site 16
T107
E
V
R
F
H
L
A
T
A
E
W
I
A
E
P
Site 17
T136
R
L
G
E
L
I
L
T
S
E
S
S
R
Y
Q
Site 18
S137
L
G
E
L
I
L
T
S
E
S
S
R
Y
Q
F
Site 19
S139
E
L
I
L
T
S
E
S
S
R
Y
Q
F
R
N
Site 20
S140
L
I
L
T
S
E
S
S
R
Y
Q
F
R
N
L
Site 21
Y142
L
T
S
E
S
S
R
Y
Q
F
R
N
L
A
D
Site 22
T159
Q
K
I
R
D
M
I
T
E
A
S
Q
T
P
K
Site 23
S162
R
D
M
I
T
E
A
S
Q
T
P
K
E
P
T
Site 24
T164
M
I
T
E
A
S
Q
T
P
K
E
P
T
K
E
Site 25
S195
L
R
Q
K
R
I
H
S
A
V
K
T
S
R
R
Site 26
T199
R
I
H
S
A
V
K
T
S
R
R
V
D
M
D
Site 27
S200
I
H
S
A
V
K
T
S
R
R
V
D
M
D
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation