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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FLOT2
Full Name:
Flotillin-2
Alias:
ECS1; ECS-1; Epidermal surface antigen; ESA; ESA1; Flotillin 2; M17S1; Membrane component, chromosome 17, surface marker 1
Type:
Adhesion
Mass (Da):
47064
Number AA:
428
UniProt ID:
Q14254
International Prot ID:
IPI00029625
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0009986
GO:0019898
GO:0005624
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
GO:0008544
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y24
G
G
C
C
G
S
D
Y
K
Q
Y
V
F
G
G
Site 2
Y27
C
G
S
D
Y
K
Q
Y
V
F
G
G
W
A
W
Site 3
S46
I
S
D
T
Q
R
I
S
L
E
I
M
T
L
Q
Site 4
T51
R
I
S
L
E
I
M
T
L
Q
P
R
C
E
D
Site 5
T61
P
R
C
E
D
V
E
T
A
E
G
V
A
L
T
Site 6
T119
R
S
I
L
G
T
L
T
V
E
Q
I
Y
Q
D
Site 7
Y124
T
L
T
V
E
Q
I
Y
Q
D
R
D
Q
F
A
Site 8
Y158
S
F
T
I
K
D
V
Y
D
K
V
D
Y
L
S
Site 9
Y163
D
V
Y
D
K
V
D
Y
L
S
S
L
G
K
T
Site 10
S165
Y
D
K
V
D
Y
L
S
S
L
G
K
T
Q
T
Site 11
S166
D
K
V
D
Y
L
S
S
L
G
K
T
Q
T
A
Site 12
T170
Y
L
S
S
L
G
K
T
Q
T
A
V
V
Q
R
Site 13
T172
S
S
L
G
K
T
Q
T
A
V
V
Q
R
D
A
Site 14
S215
A
D
T
K
I
A
D
S
K
R
A
F
E
L
Q
Site 15
S224
R
A
F
E
L
Q
K
S
A
F
S
E
E
V
N
Site 16
T234
S
E
E
V
N
I
K
T
A
E
A
Q
L
A
Y
Site 17
Y241
T
A
E
A
Q
L
A
Y
E
L
Q
G
A
R
E
Site 18
T278
E
A
Q
E
I
L
R
T
D
K
E
L
I
A
T
Site 19
T285
T
D
K
E
L
I
A
T
V
R
R
P
A
E
A
Site 20
Y348
M
K
L
K
A
E
A
Y
Q
K
Y
G
D
A
A
Site 21
Y351
K
A
E
A
Y
Q
K
Y
G
D
A
A
K
M
A
Site 22
S389
V
V
L
S
G
D
N
S
K
V
T
S
E
V
N
Site 23
S393
G
D
N
S
K
V
T
S
E
V
N
R
L
L
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation