KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
FKBP8
Full Name:
Peptidyl-prolyl cis-trans isomerase FKBP8
Alias:
38 kDa FK-506 binding protein; FK506 binding protein 8, 38kDa; FK506-binding protein 8 (38kD); FKB8; FKBP38; FKBPR38
Type:
Chaperone; EC 5.2.1.8; Isomerase
Mass (Da):
38408
Number AA:
355
UniProt ID:
Q14318
International Prot ID:
IPI00640341
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005739
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0003755
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0044419
GO:0007242
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
A
S
C
A
E
P
S
E
P
S
A
P
L
P
Site 2
S50
E
E
E
E
D
D
L
S
E
L
P
P
L
E
D
Site 3
T106
N
G
L
L
R
K
K
T
L
V
P
G
P
P
G
Site 4
S114
L
V
P
G
P
P
G
S
S
R
P
V
K
G
Q
Site 5
S115
V
P
G
P
P
G
S
S
R
P
V
K
G
Q
V
Site 6
Y177
M
V
T
A
D
S
K
Y
C
Y
G
P
Q
G
R
Site 7
Y179
T
A
D
S
K
Y
C
Y
G
P
Q
G
R
S
P
Site 8
S185
C
Y
G
P
Q
G
R
S
P
Y
I
P
P
H
A
Site 9
Y187
G
P
Q
G
R
S
P
Y
I
P
P
H
A
A
L
Site 10
Y232
R
E
C
G
N
A
H
Y
Q
R
A
D
F
V
L
Site 11
Y244
F
V
L
A
A
N
S
Y
D
L
A
I
K
A
I
Site 12
T260
S
S
A
K
V
D
M
T
F
E
E
E
A
Q
L
Site 13
S281
C
L
N
N
L
A
A
S
Q
L
K
L
D
H
Y
Site 14
Y288
S
Q
L
K
L
D
H
Y
R
A
A
L
R
S
C
Site 15
S294
H
Y
R
A
A
L
R
S
C
S
L
V
L
E
H
Site 16
S296
R
A
A
L
R
S
C
S
L
V
L
E
H
Q
P
Site 17
Y322
V
L
A
Q
Q
G
E
Y
S
E
A
I
P
I
L
Site 18
S323
L
A
Q
Q
G
E
Y
S
E
A
I
P
I
L
R
Site 19
S347
K
T
I
H
A
E
L
S
K
L
V
K
K
H
A
Site 20
T359
K
H
A
A
Q
R
S
T
E
T
A
L
Y
R
K
Site 21
Y364
R
S
T
E
T
A
L
Y
R
K
M
L
G
N
P
Site 22
S372
R
K
M
L
G
N
P
S
R
L
P
A
K
C
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation