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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MYBPC2
Full Name:
Myosin-binding protein C, fast-type
Alias:
C-protein, skeletal muscle fast isoform; C-protein, skeletal muscle fast-isoform; Fast MyBP-C; Fast-type muscle myosin-binding-protein C; MGC163408; MYBPC; MYBPCF; Myosin binding protein C, fast type; MYPC2
Type:
Myosin binding protein
Mass (Da):
128143
Number AA:
1142
UniProt ID:
Q14324
International Prot ID:
IPI00030104
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0032982
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0008307
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S44
E
A
P
P
E
D
Q
S
P
T
A
E
E
P
T
Site 2
S60
V
F
L
K
K
P
D
S
V
S
V
E
T
G
K
Site 3
S62
L
K
K
P
D
S
V
S
V
E
T
G
K
D
A
Site 4
T85
K
E
L
P
D
K
P
T
I
K
W
F
K
G
K
Site 5
S98
G
K
W
L
E
L
G
S
K
S
G
A
R
F
S
Site 6
S100
W
L
E
L
G
S
K
S
G
A
R
F
S
F
K
Site 7
S105
S
K
S
G
A
R
F
S
F
K
E
S
H
N
S
Site 8
S109
A
R
F
S
F
K
E
S
H
N
S
A
S
N
V
Site 9
S112
S
F
K
E
S
H
N
S
A
S
N
V
Y
T
V
Site 10
T118
N
S
A
S
N
V
Y
T
V
E
L
H
I
G
K
Site 11
Y133
V
V
L
G
D
R
G
Y
Y
R
L
E
V
K
A
Site 12
Y134
V
L
G
D
R
G
Y
Y
R
L
E
V
K
A
K
Site 13
S161
E
A
P
R
Q
D
A
S
G
Q
S
L
E
S
F
Site 14
S164
R
Q
D
A
S
G
Q
S
L
E
S
F
K
R
T
Site 15
S167
A
S
G
Q
S
L
E
S
F
K
R
T
S
E
K
Site 16
T171
S
L
E
S
F
K
R
T
S
E
K
K
S
D
T
Site 17
S172
L
E
S
F
K
R
T
S
E
K
K
S
D
T
A
Site 18
S176
K
R
T
S
E
K
K
S
D
T
A
G
E
L
D
Site 19
S185
T
A
G
E
L
D
F
S
G
L
L
K
K
R
E
Site 20
S224
L
L
K
G
A
K
K
S
E
Y
E
K
I
A
F
Site 21
Y226
K
G
A
K
K
S
E
Y
E
K
I
A
F
Q
Y
Site 22
S255
A
K
V
E
V
K
K
S
A
A
F
T
K
K
L
Site 23
T259
V
K
K
S
A
A
F
T
K
K
L
D
P
A
Y
Site 24
Y266
T
K
K
L
D
P
A
Y
Q
V
D
R
G
N
K
Site 25
T286
E
I
S
D
P
D
L
T
L
K
W
F
K
N
G
Site 26
S299
N
G
Q
E
I
K
P
S
S
K
Y
V
F
E
N
Site 27
S300
G
Q
E
I
K
P
S
S
K
Y
V
F
E
N
V
Site 28
Y302
E
I
K
P
S
S
K
Y
V
F
E
N
V
G
K
Site 29
T314
V
G
K
K
R
I
L
T
I
N
K
C
T
L
A
Site 30
Y326
T
L
A
D
D
A
A
Y
E
V
A
V
K
D
E
Site 31
T337
V
K
D
E
K
C
F
T
E
L
F
V
K
E
P
Site 32
S390
V
E
L
T
R
E
D
S
F
K
A
R
Y
R
F
Site 33
S409
K
R
H
I
L
I
F
S
D
V
V
Q
E
D
R
Site 34
Y419
V
Q
E
D
R
G
R
Y
Q
V
I
T
N
G
G
Site 35
T423
R
G
R
Y
Q
V
I
T
N
G
G
Q
C
E
A
Site 36
T449
L
Q
D
I
A
D
L
T
V
K
A
S
E
Q
A
Site 37
S463
A
V
F
K
C
E
V
S
D
E
K
V
T
G
K
Site 38
Y472
E
K
V
T
G
K
W
Y
K
N
G
V
E
V
R
Site 39
S481
N
G
V
E
V
R
P
S
K
R
I
T
I
S
H
Site 40
T485
V
R
P
S
K
R
I
T
I
S
H
V
G
R
F
Site 41
S487
P
S
K
R
I
T
I
S
H
V
G
R
F
H
K
Site 42
Y508
R
P
E
D
E
G
D
Y
T
F
V
P
D
G
Y
Site 43
T509
P
E
D
E
G
D
Y
T
F
V
P
D
G
Y
A
Site 44
S519
P
D
G
Y
A
L
G
S
L
S
A
K
L
N
F
Site 45
T588
K
G
D
E
V
F
T
T
T
E
G
R
T
R
I
Site 46
Y1003
D
L
I
V
G
N
E
Y
Y
F
R
V
Y
T
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation