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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GCKR
Full Name:
Glucokinase regulatory protein
Alias:
Type:
Mass (Da):
68701
Number AA:
625
UniProt ID:
Q14397
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T13
R
F
Q
H
V
I
E
T
P
E
P
G
K
W
E
Site 2
Y24
G
K
W
E
L
S
G
Y
E
A
A
V
P
I
T
Site 3
S34
A
V
P
I
T
E
K
S
N
P
L
T
Q
D
L
Site 4
T38
T
E
K
S
N
P
L
T
Q
D
L
D
K
A
D
Site 5
S69
Q
E
E
G
Q
A
L
S
T
Y
Q
R
L
Y
S
Site 6
Y71
E
G
Q
A
L
S
T
Y
Q
R
L
Y
S
E
S
Site 7
Y75
L
S
T
Y
Q
R
L
Y
S
E
S
I
L
T
T
Site 8
S76
S
T
Y
Q
R
L
Y
S
E
S
I
L
T
T
M
Site 9
S78
Y
Q
R
L
Y
S
E
S
I
L
T
T
M
V
Q
Site 10
Y136
G
Q
K
P
L
Y
T
Y
L
I
A
G
G
D
R
Site 11
S144
L
I
A
G
G
D
R
S
V
V
A
S
R
E
G
Site 12
S148
G
D
R
S
V
V
A
S
R
E
G
T
E
D
S
Site 13
T152
V
V
A
S
R
E
G
T
E
D
S
A
L
H
G
Site 14
S155
S
R
E
G
T
E
D
S
A
L
H
G
I
E
E
Site 15
S224
D
P
I
E
D
W
S
S
T
F
R
Q
V
A
E
Site 16
T225
P
I
E
D
W
S
S
T
F
R
Q
V
A
E
R
Site 17
S255
A
I
G
P
E
G
L
S
G
S
S
R
M
K
G
Site 18
S257
G
P
E
G
L
S
G
S
S
R
M
K
G
G
S
Site 19
S258
P
E
G
L
S
G
S
S
R
M
K
G
G
S
A
Site 20
S264
S
S
R
M
K
G
G
S
A
T
K
I
L
L
E
Site 21
T280
L
L
L
A
A
H
K
T
V
D
Q
G
I
A
A
Site 22
T306
F
E
R
A
H
Q
V
T
Y
S
Q
S
P
K
I
Site 23
S308
R
A
H
Q
V
T
Y
S
Q
S
P
K
I
A
T
Site 24
S310
H
Q
V
T
Y
S
Q
S
P
K
I
A
T
L
M
Site 25
T315
S
Q
S
P
K
I
A
T
L
M
K
S
V
S
T
Site 26
S319
K
I
A
T
L
M
K
S
V
S
T
S
L
E
K
Site 27
S321
A
T
L
M
K
S
V
S
T
S
L
E
K
K
G
Site 28
S323
L
M
K
S
V
S
T
S
L
E
K
K
G
H
V
Site 29
Y331
L
E
K
K
G
H
V
Y
L
V
G
W
Q
T
L
Site 30
T352
D
G
V
E
C
I
H
T
F
G
A
D
F
R
D
Site 31
T386
T
N
Q
G
P
Q
F
T
F
S
Q
E
D
F
L
Site 32
S388
Q
G
P
Q
F
T
F
S
Q
E
D
F
L
T
S
Site 33
S395
S
Q
E
D
F
L
T
S
I
L
P
S
L
T
E
Site 34
T417
F
T
L
D
D
N
L
T
E
V
Q
T
I
V
E
Site 35
Y468
W
P
L
L
F
F
E
Y
E
G
N
F
I
Q
K
Site 36
S481
Q
K
F
Q
R
E
L
S
T
K
W
V
L
N
T
Site 37
S511
H
M
L
D
L
R
I
S
N
S
K
L
F
W
R
Site 38
S513
L
D
L
R
I
S
N
S
K
L
F
W
R
A
L
Site 39
S527
L
A
M
L
Q
R
F
S
G
Q
S
K
A
R
C
Site 40
S530
L
Q
R
F
S
G
Q
S
K
A
R
C
I
E
S
Site 41
S549
I
H
F
P
Q
P
L
S
D
D
I
R
A
A
P
Site 42
T613
A
G
P
G
Q
K
R
T
A
D
P
L
E
I
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation