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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GPR176
Full Name:
Probable G-protein coupled receptor 176
Alias:
HB-954
Type:
Mass (Da):
56998
Number AA:
515
UniProt ID:
Q14439
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
G
H
N
G
S
W
I
S
P
N
A
S
E
P
H
Site 2
S13
S
W
I
S
P
N
A
S
E
P
H
N
A
S
G
Site 3
Y40
E
F
G
E
A
Q
L
Y
R
Q
F
T
T
T
V
Site 4
T70
L
W
S
T
C
R
T
T
V
F
K
S
V
T
N
Site 5
S145
I
A
L
D
R
Y
Y
S
V
L
Y
P
L
E
R
Site 6
Y148
D
R
Y
Y
S
V
L
Y
P
L
E
R
K
I
S
Site 7
S155
Y
P
L
E
R
K
I
S
D
A
K
S
R
E
L
Site 8
S159
R
K
I
S
D
A
K
S
R
E
L
V
M
Y
I
Site 9
S233
I
L
I
R
R
A
L
S
A
S
Q
K
K
K
V
Site 10
S235
I
R
R
A
L
S
A
S
Q
K
K
K
V
I
I
Site 11
T251
A
L
R
T
P
Q
N
T
I
S
I
P
Y
A
S
Site 12
S258
T
I
S
I
P
Y
A
S
Q
R
E
A
E
L
H
Site 13
Y342
L
V
Q
L
H
H
R
Y
S
R
R
N
V
V
S
Site 14
S343
V
Q
L
H
H
R
Y
S
R
R
N
V
V
S
T
Site 15
S349
Y
S
R
R
N
V
V
S
T
G
S
G
M
A
E
Site 16
T350
S
R
R
N
V
V
S
T
G
S
G
M
A
E
A
Site 17
S358
G
S
G
M
A
E
A
S
L
E
P
S
I
R
S
Site 18
S362
A
E
A
S
L
E
P
S
I
R
S
G
S
Q
L
Site 19
S365
S
L
E
P
S
I
R
S
G
S
Q
L
L
E
M
Site 20
S367
E
P
S
I
R
S
G
S
Q
L
L
E
M
F
H
Site 21
S390
P
T
E
D
E
E
E
S
E
A
K
Y
I
G
S
Site 22
Y394
E
E
E
S
E
A
K
Y
I
G
S
A
D
F
Q
Site 23
S397
S
E
A
K
Y
I
G
S
A
D
F
Q
A
K
E
Site 24
T408
Q
A
K
E
I
F
S
T
C
L
E
G
E
Q
G
Site 25
S421
Q
G
P
Q
F
A
P
S
A
P
P
L
S
T
V
Site 26
S426
A
P
S
A
P
P
L
S
T
V
D
S
V
S
Q
Site 27
T427
P
S
A
P
P
L
S
T
V
D
S
V
S
Q
V
Site 28
T444
A
A
P
V
E
P
E
T
F
P
D
K
Y
S
L
Site 29
Y449
P
E
T
F
P
D
K
Y
S
L
Q
F
G
F
G
Site 30
S450
E
T
F
P
D
K
Y
S
L
Q
F
G
F
G
P
Site 31
S466
E
L
P
P
Q
W
L
S
E
T
R
N
S
K
K
Site 32
S471
W
L
S
E
T
R
N
S
K
K
R
L
L
P
P
Site 33
T482
L
L
P
P
L
G
N
T
P
E
E
L
I
Q
T
Site 34
T489
T
P
E
E
L
I
Q
T
K
V
P
K
V
G
R
Site 35
S502
G
R
V
E
R
K
M
S
R
N
N
K
V
S
I
Site 36
S508
M
S
R
N
N
K
V
S
I
F
P
K
V
D
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation