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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SPARCL1
Full Name:
SPARC-like protein 1
Alias:
Hevin; High endothelial venule protein; MAST 9; MAST9; SPARC-like 1; SPRL1
Type:
Mass (Da):
75189
Number AA:
664
UniProt ID:
Q14515
International Prot ID:
IPI00296777
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005578
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
P
T
N
A
R
L
L
S
D
H
S
K
P
T
A
Site 2
S28
A
R
L
L
S
D
H
S
K
P
T
A
E
T
V
Site 3
T34
H
S
K
P
T
A
E
T
V
A
P
D
N
T
A
Site 4
T40
E
T
V
A
P
D
N
T
A
I
P
S
L
R
A
Site 5
S44
P
D
N
T
A
I
P
S
L
R
A
E
A
E
E
Site 6
S59
N
E
K
E
T
A
V
S
T
E
D
D
S
H
H
Site 7
T60
E
K
E
T
A
V
S
T
E
D
D
S
H
H
K
Site 8
S64
A
V
S
T
E
D
D
S
H
H
K
A
E
K
S
Site 9
S71
S
H
H
K
A
E
K
S
S
V
L
K
S
K
E
Site 10
S72
H
H
K
A
E
K
S
S
V
L
K
S
K
E
E
Site 11
S76
E
K
S
S
V
L
K
S
K
E
E
S
H
E
Q
Site 12
S80
V
L
K
S
K
E
E
S
H
E
Q
S
A
E
Q
Site 13
S84
K
E
E
S
H
E
Q
S
A
E
Q
G
K
S
S
Site 14
S90
Q
S
A
E
Q
G
K
S
S
S
Q
E
L
G
L
Site 15
S92
A
E
Q
G
K
S
S
S
Q
E
L
G
L
K
D
Site 16
S103
G
L
K
D
Q
E
D
S
D
G
H
L
S
V
N
Site 17
S108
E
D
S
D
G
H
L
S
V
N
L
E
Y
A
P
Site 18
T116
V
N
L
E
Y
A
P
T
E
G
T
L
D
I
K
Site 19
S127
L
D
I
K
E
D
M
S
E
P
Q
E
K
K
L
Site 20
S135
E
P
Q
E
K
K
L
S
E
N
T
D
F
L
A
Site 21
S146
D
F
L
A
P
G
V
S
S
F
T
D
S
N
Q
Site 22
S147
F
L
A
P
G
V
S
S
F
T
D
S
N
Q
Q
Site 23
T149
A
P
G
V
S
S
F
T
D
S
N
Q
Q
E
S
Site 24
S151
G
V
S
S
F
T
D
S
N
Q
Q
E
S
I
T
Site 25
Y170
N
Q
E
Q
P
R
N
Y
S
H
H
Q
L
N
R
Site 26
S171
Q
E
Q
P
R
N
Y
S
H
H
Q
L
N
R
S
Site 27
S178
S
H
H
Q
L
N
R
S
S
K
H
S
Q
G
L
Site 28
S179
H
H
Q
L
N
R
S
S
K
H
S
Q
G
L
R
Site 29
S182
L
N
R
S
S
K
H
S
Q
G
L
R
D
Q
G
Site 30
T222
N
D
N
Q
E
R
K
T
E
L
P
R
E
H
A
Site 31
S231
L
P
R
E
H
A
N
S
K
Q
E
E
D
N
T
Site 32
T238
S
K
Q
E
E
D
N
T
Q
S
D
D
I
L
E
Site 33
S247
S
D
D
I
L
E
E
S
D
Q
P
T
Q
V
S
Site 34
T251
L
E
E
S
D
Q
P
T
Q
V
S
K
M
Q
E
Site 35
S272
N
Q
E
Q
E
D
N
S
N
A
E
M
E
E
E
Site 36
S282
E
M
E
E
E
N
A
S
N
V
N
K
H
I
Q
Site 37
S295
I
Q
E
T
E
W
Q
S
Q
E
G
K
T
G
L
Site 38
T315
H
K
E
T
E
E
K
T
V
S
E
A
L
L
M
Site 39
S317
E
T
E
E
K
T
V
S
E
A
L
L
M
E
P
Site 40
T330
E
P
T
D
D
G
N
T
T
P
R
N
H
G
V
Site 41
T331
P
T
D
D
G
N
T
T
P
R
N
H
G
V
D
Site 42
T350
D
D
G
D
D
G
G
T
D
G
P
R
H
S
A
Site 43
S356
G
T
D
G
P
R
H
S
A
S
D
D
Y
F
I
Site 44
S358
D
G
P
R
H
S
A
S
D
D
Y
F
I
P
S
Site 45
Y361
R
H
S
A
S
D
D
Y
F
I
P
S
Q
A
F
Site 46
S365
S
D
D
Y
F
I
P
S
Q
A
F
L
E
A
E
Site 47
S376
L
E
A
E
R
A
Q
S
I
A
Y
H
L
K
I
Site 48
T398
H
E
N
E
N
I
G
T
T
E
P
G
E
H
Q
Site 49
S414
A
K
K
A
E
N
S
S
N
E
E
E
T
S
S
Site 50
T419
N
S
S
N
E
E
E
T
S
S
E
G
N
M
R
Site 51
S420
S
S
N
E
E
E
T
S
S
E
G
N
M
R
V
Site 52
S421
S
N
E
E
E
T
S
S
E
G
N
M
R
V
H
Site 53
Y479
C
G
T
D
N
Q
T
Y
A
S
S
C
H
L
F
Site 54
T488
S
S
C
H
L
F
A
T
K
C
R
L
E
G
T
Site 55
Y505
G
H
Q
L
Q
L
D
Y
F
G
A
C
K
S
I
Site 56
Y539
K
N
I
L
M
Q
L
Y
E
A
N
S
E
H
A
Site 57
Y548
A
N
S
E
H
A
G
Y
L
N
E
K
Q
R
N
Site 58
Y561
R
N
K
V
K
K
I
Y
L
D
E
K
R
L
L
Site 59
Y585
L
R
D
F
K
K
N
Y
H
M
Y
V
Y
P
V
Site 60
T609
H
P
M
D
R
V
L
T
H
S
E
L
A
P
L
Site 61
S611
M
D
R
V
L
T
H
S
E
L
A
P
L
R
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation