KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
HABP2
Full Name:
Hyaluronan-binding protein 2
Alias:
EC 3.4.21.-; Factor seven-activating protease; Factor VII activating protein; Factor VII-activating protease; FSAP; HABP; Hepatocyte growth factor activator-like; HGFAL; Hyaluronan binding protein 2; Hyaluronan-binding 2; PHBP; Plasma hyaluronan binding protein; Plasma hyaluronan-binding
Type:
Adhesion; Protease; EC 3.4.21.-
Mass (Da):
62672
Number AA:
560
UniProt ID:
Q14520
International Prot ID:
IPI00746623
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005615
Uniprot
OncoNet
Molecular Function:
GO:0005539
GO:0004252
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
GO:0006508
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S32
S
L
M
S
L
L
E
S
L
D
P
D
W
T
P
Site 2
T38
E
S
L
D
P
D
W
T
P
D
Q
Y
D
Y
S
Site 3
Y42
P
D
W
T
P
D
Q
Y
D
Y
S
Y
E
D
Y
Site 4
Y44
W
T
P
D
Q
Y
D
Y
S
Y
E
D
Y
N
Q
Site 5
S45
T
P
D
Q
Y
D
Y
S
Y
E
D
Y
N
Q
E
Site 6
Y46
P
D
Q
Y
D
Y
S
Y
E
D
Y
N
Q
E
E
Site 7
Y49
Y
D
Y
S
Y
E
D
Y
N
Q
E
E
N
T
S
Site 8
S56
Y
N
Q
E
E
N
T
S
S
T
L
T
H
A
E
Site 9
S57
N
Q
E
E
N
T
S
S
T
L
T
H
A
E
N
Site 10
T60
E
N
T
S
S
T
L
T
H
A
E
N
P
D
W
Site 11
Y68
H
A
E
N
P
D
W
Y
Y
T
E
D
Q
A
D
Site 12
Y69
A
E
N
P
D
W
Y
Y
T
E
D
Q
A
D
P
Site 13
T128
G
R
G
Q
C
L
I
T
Q
S
P
P
Y
Y
R
Site 14
Y133
L
I
T
Q
S
P
P
Y
Y
R
C
V
C
K
H
Site 15
Y134
I
T
Q
S
P
P
Y
Y
R
C
V
C
K
H
P
Site 16
Y142
R
C
V
C
K
H
P
Y
T
G
P
S
C
S
Q
Site 17
T143
C
V
C
K
H
P
Y
T
G
P
S
C
S
Q
V
Site 18
S146
K
H
P
Y
T
G
P
S
C
S
Q
V
V
P
V
Site 19
S148
P
Y
T
G
P
S
C
S
Q
V
V
P
V
C
R
Site 20
S166
C
Q
N
G
A
T
C
S
R
H
K
R
R
S
K
Site 21
Y195
E
I
G
S
D
D
C
Y
V
G
D
G
Y
S
Y
Site 22
Y200
D
C
Y
V
G
D
G
Y
S
Y
R
G
K
M
N
Site 23
Y202
Y
V
G
D
G
Y
S
Y
R
G
K
M
N
R
T
Site 24
Y270
N
D
K
V
K
W
E
Y
C
D
V
S
A
C
S
Site 25
Y283
C
S
A
Q
D
V
A
Y
P
E
E
S
P
T
E
Site 26
S287
D
V
A
Y
P
E
E
S
P
T
E
P
S
T
K
Site 27
T289
A
Y
P
E
E
S
P
T
E
P
S
T
K
L
P
Site 28
T293
E
S
P
T
E
P
S
T
K
L
P
G
F
D
S
Site 29
S300
T
K
L
P
G
F
D
S
C
G
K
T
E
I
A
Site 30
T304
G
F
D
S
C
G
K
T
E
I
A
E
R
K
I
Site 31
Y315
E
R
K
I
K
R
I
Y
G
G
F
K
S
T
A
Site 32
S330
G
K
H
P
W
Q
A
S
L
Q
S
S
L
P
L
Site 33
T338
L
Q
S
S
L
P
L
T
I
S
M
P
Q
G
H
Site 34
S389
K
E
E
F
H
E
Q
S
F
R
V
E
K
I
F
Site 35
Y398
R
V
E
K
I
F
K
Y
S
H
Y
N
E
R
D
Site 36
Y401
K
I
F
K
Y
S
H
Y
N
E
R
D
E
I
P
Site 37
T433
L
E
S
K
Y
V
K
T
V
C
L
P
D
G
S
Site 38
S440
T
V
C
L
P
D
G
S
F
P
S
G
S
E
C
Site 39
S443
L
P
D
G
S
F
P
S
G
S
E
C
H
I
S
Site 40
S445
D
G
S
F
P
S
G
S
E
C
H
I
S
G
W
Site 41
S450
S
G
S
E
C
H
I
S
G
W
G
V
T
E
T
Site 42
T457
S
G
W
G
V
T
E
T
G
K
G
S
R
Q
L
Site 43
T475
K
V
K
L
I
A
N
T
L
C
N
S
R
Q
L
Site 44
Y483
L
C
N
S
R
Q
L
Y
D
H
M
I
D
D
S
Site 45
T504
L
Q
K
P
G
Q
D
T
C
Q
G
D
S
G
G
Site 46
T514
G
D
S
G
G
P
L
T
C
E
K
D
G
T
Y
Site 47
Y521
T
C
E
K
D
G
T
Y
Y
V
Y
G
I
V
S
Site 48
Y522
C
E
K
D
G
T
Y
Y
V
Y
G
I
V
S
W
Site 49
Y540
C
G
K
R
P
G
V
Y
T
Q
V
T
K
F
L
Site 50
T541
G
K
R
P
G
V
Y
T
Q
V
T
K
F
L
N
Site 51
T544
P
G
V
Y
T
Q
V
T
K
F
L
N
W
I
K
Site 52
T553
F
L
N
W
I
K
A
T
I
K
S
E
S
G
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation