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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HNF4G
Full Name:
Hepatocyte nuclear factor 4-gamma
Alias:
HNF-4-gamma; NR2A2; Nuclear receptor subfamily 2 group A member 2
Type:
Nucleolus, Cytoplasm, Nucleus protein
Mass (Da):
45877
Number AA:
408
UniProt ID:
Q14541
International Prot ID:
IPI00291564
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0005496
GO:0003707
PhosphoSite+
KinaseNET
Biological Process:
GO:0006357
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T20
A
I
C
G
D
R
A
T
G
K
H
Y
G
A
S
Site 2
Y24
D
R
A
T
G
K
H
Y
G
A
S
S
C
D
G
Site 3
S27
T
G
K
H
Y
G
A
S
S
C
D
G
C
K
G
Site 4
S28
G
K
H
Y
G
A
S
S
C
D
G
C
K
G
F
Site 5
S43
F
R
R
S
I
R
K
S
H
V
Y
S
C
R
F
Site 6
Y46
S
I
R
K
S
H
V
Y
S
C
R
F
S
R
Q
Site 7
Y66
D
K
R
N
Q
C
R
Y
C
R
L
R
K
C
F
Site 8
S90
Q
N
E
R
D
R
I
S
T
R
R
S
T
F
D
Site 9
T91
N
E
R
D
R
I
S
T
R
R
S
T
F
D
G
Site 10
S94
D
R
I
S
T
R
R
S
T
F
D
G
S
N
I
Site 11
T95
R
I
S
T
R
R
S
T
F
D
G
S
N
I
P
Site 12
S99
R
R
S
T
F
D
G
S
N
I
P
S
I
N
T
Site 13
S103
F
D
G
S
N
I
P
S
I
N
T
L
A
Q
A
Site 14
S114
L
A
Q
A
E
V
R
S
R
Q
I
S
V
S
S
Site 15
S118
E
V
R
S
R
Q
I
S
V
S
S
P
G
S
S
Site 16
S120
R
S
R
Q
I
S
V
S
S
P
G
S
S
T
D
Site 17
S121
S
R
Q
I
S
V
S
S
P
G
S
S
T
D
I
Site 18
S124
I
S
V
S
S
P
G
S
S
T
D
I
N
V
K
Site 19
S125
S
V
S
S
P
G
S
S
T
D
I
N
V
K
K
Site 20
T126
V
S
S
P
G
S
S
T
D
I
N
V
K
K
I
Site 21
T185
E
H
L
L
L
G
A
T
K
R
S
M
M
Y
K
Site 22
S207
N
Y
V
I
H
R
N
S
C
E
V
E
I
S
R
Site 23
S213
N
S
C
E
V
E
I
S
R
V
A
N
R
V
L
Site 24
S254
D
P
D
A
K
G
L
S
D
P
V
K
I
K
N
Site 25
Y273
V
Q
I
G
L
E
D
Y
I
N
D
R
Q
Y
D
Site 26
Y279
D
Y
I
N
D
R
Q
Y
D
S
R
G
R
F
G
Site 27
S281
I
N
D
R
Q
Y
D
S
R
G
R
F
G
E
L
Site 28
S330
E
M
L
L
G
G
A
S
N
D
G
S
H
L
H
Site 29
S334
G
G
A
S
N
D
G
S
H
L
H
H
P
M
H
Site 30
S345
H
P
M
H
P
H
L
S
Q
D
P
L
T
G
Q
Site 31
S369
L
V
H
A
D
Q
I
S
T
P
E
T
P
L
P
Site 32
T370
V
H
A
D
Q
I
S
T
P
E
T
P
L
P
S
Site 33
T373
D
Q
I
S
T
P
E
T
P
L
P
S
P
P
Q
Site 34
S377
T
P
E
T
P
L
P
S
P
P
Q
G
S
G
Q
Site 35
S395
K
I
A
A
N
Q
A
S
V
I
S
H
Q
H
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation