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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SEMA3A
Full Name:
Semaphorin-3A
Alias:
coll-1; collapsin 1; Hsema-I; SEM3A; sema domain, immunoglobulin domain (Ig) short basic domain, secreted (semaphorin) 3A; Sema III; SEMA1; SEMAD; SEMAIII; SEMAL; semaphorin III; SemD
Type:
Secreted protein
Mass (Da):
88890
Number AA:
UniProt ID:
Q14563
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0004872
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y22
L
L
T
A
R
A
N
Y
Q
N
G
K
N
N
V
Site 2
S35
N
V
P
R
L
K
L
S
Y
K
E
M
L
E
S
Site 3
Y36
V
P
R
L
K
L
S
Y
K
E
M
L
E
S
N
Site 4
T47
L
E
S
N
N
V
I
T
F
N
G
L
A
N
S
Site 5
S54
T
F
N
G
L
A
N
S
S
S
Y
H
T
F
L
Site 6
S56
N
G
L
A
N
S
S
S
Y
H
T
F
L
L
D
Site 7
T59
A
N
S
S
S
Y
H
T
F
L
L
D
E
E
R
Site 8
Y70
D
E
E
R
S
R
L
Y
V
G
A
K
D
H
I
Site 9
Y97
K
I
V
W
P
V
S
Y
T
R
R
D
E
C
K
Site 10
Y130
A
Y
N
Q
T
H
L
Y
A
C
G
T
G
A
F
Site 11
Y143
A
F
H
P
I
C
T
Y
I
E
I
G
H
H
P
Site 12
S160
N
I
F
K
L
E
N
S
H
F
E
N
G
R
G
Site 13
S169
F
E
N
G
R
G
K
S
P
Y
D
P
K
L
L
Site 14
Y171
N
G
R
G
K
S
P
Y
D
P
K
L
L
T
A
Site 15
T190
D
G
E
L
Y
S
G
T
A
A
D
F
M
G
R
Site 16
S218
I
R
T
E
Q
H
D
S
R
W
L
N
D
P
K
Site 17
S228
L
N
D
P
K
F
I
S
A
H
L
I
S
E
S
Site 18
S233
F
I
S
A
H
L
I
S
E
S
D
N
P
E
D
Site 19
S235
S
A
H
L
I
S
E
S
D
N
P
E
D
D
K
Site 20
Y244
N
P
E
D
D
K
V
Y
F
F
F
R
E
N
A
Site 21
T261
G
E
H
S
G
K
A
T
H
A
R
I
G
Q
I
Site 22
T303
P
G
P
N
G
I
D
T
H
F
D
E
L
Q
D
Site 23
S332
Y
G
V
F
T
T
S
S
N
I
F
K
G
S
A
Site 24
Y343
K
G
S
A
V
C
M
Y
S
M
S
D
V
R
R
Site 25
Y356
R
R
V
F
L
G
P
Y
A
H
R
D
G
P
N
Site 26
Y364
A
H
R
D
G
P
N
Y
Q
W
V
P
Y
Q
G
Site 27
Y369
P
N
Y
Q
W
V
P
Y
Q
G
R
V
P
Y
P
Site 28
Y375
P
Y
Q
G
R
V
P
Y
P
R
P
G
T
C
P
Site 29
T380
V
P
Y
P
R
P
G
T
C
P
S
K
T
F
G
Site 30
S383
P
R
P
G
T
C
P
S
K
T
F
G
G
F
D
Site 31
T385
P
G
T
C
P
S
K
T
F
G
G
F
D
S
T
Site 32
S391
K
T
F
G
G
F
D
S
T
K
D
L
P
D
D
Site 33
T401
D
L
P
D
D
V
I
T
F
A
R
S
H
P
A
Site 34
S405
D
V
I
T
F
A
R
S
H
P
A
M
Y
N
P
Site 35
Y410
A
R
S
H
P
A
M
Y
N
P
V
F
P
M
N
Site 36
T425
N
R
P
I
V
I
K
T
D
V
N
Y
Q
F
T
Site 37
Y446
V
D
A
E
D
G
Q
Y
D
V
M
F
I
G
T
Site 38
Y470
S
I
P
K
E
T
W
Y
D
L
E
E
V
L
L
Site 39
Y502
S
T
K
Q
Q
Q
L
Y
I
G
S
T
A
G
V
Site 40
Y520
P
L
H
R
C
D
I
Y
G
K
A
C
A
E
C
Site 41
Y534
C
C
L
A
R
D
P
Y
C
A
W
D
G
S
A
Site 42
Y545
D
G
S
A
C
S
R
Y
F
P
T
A
K
R
R
Site 43
T553
F
P
T
A
K
R
R
T
R
R
Q
D
I
R
N
Site 44
T565
I
R
N
G
D
P
L
T
H
C
S
D
L
H
H
Site 45
Y586
S
P
E
E
R
I
I
Y
G
V
E
N
S
S
T
Site 46
T593
Y
G
V
E
N
S
S
T
F
L
E
C
S
P
K
Site 47
S598
S
S
T
F
L
E
C
S
P
K
S
Q
R
A
L
Site 48
S601
F
L
E
C
S
P
K
S
Q
R
A
L
V
Y
W
Site 49
S638
D
Q
G
L
L
L
R
S
L
Q
Q
K
D
S
G
Site 50
S644
R
S
L
Q
Q
K
D
S
G
N
Y
L
C
H
A
Site 51
S686
K
D
D
D
G
D
G
S
K
T
K
E
M
S
N
Site 52
T688
D
D
G
D
G
S
K
T
K
E
M
S
N
S
M
Site 53
S692
G
S
K
T
K
E
M
S
N
S
M
T
P
S
Q
Site 54
S694
K
T
K
E
M
S
N
S
M
T
P
S
Q
K
V
Site 55
T696
K
E
M
S
N
S
M
T
P
S
Q
K
V
W
Y
Site 56
S698
M
S
N
S
M
T
P
S
Q
K
V
W
Y
R
D
Site 57
T740
R
R
Q
R
P
G
H
T
P
G
N
S
N
K
W
Site 58
T761
K
K
G
R
N
R
R
T
H
E
F
E
R
A
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation