PhosphoNET

           
Protein Info 
   
Short Name:  Mad4
Full Name:  Max dimerization protein 4
Alias:  MAX dimerization 4; Max-associated 4; MST149; MSTP149
Type:  Nucleus protein
Mass (Da):  23528
Number AA:  209
UniProt ID:  Q14582
International Prot ID:  IPI00031584
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634     Uniprot OncoNet
Molecular Function:  GO:0003677  GO:0003714   PhosphoSite+ KinaseNET
Biological Process:  GO:0008285  GO:0000122  GO:0006350 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y15ILLEAAEYLERRDRE
Site 2Y27DREAEHGYASVLPFD
Site 3S29EAEHGYASVLPFDGD
Site 4T42GDFAREKTKAAGLVR
Site 5S56RKAPNNRSSHNELEK
Site 6S57KAPNNRSSHNELEKH
Site 7Y72RRAKLRLYLEQLKQL
Site 8S86LVPLGPDSTRHTTLS
Site 9T90GPDSTRHTTLSLLKR
Site 10T91PDSTRHTTLSLLKRA
Site 11S93STRHTTLSLLKRAKV
Site 12S114EQDRRALSIKEQLQQ
Site 13S134KRRLEQLSVQSVERV
Site 14T143QSVERVRTDSTGSAV
Site 15S145VERVRTDSTGSAVST
Site 16S151DSTGSAVSTDDSEQE
Site 17T152STGSAVSTDDSEQEV
Site 18S155SAVSTDDSEQEVDIE
Site 19S173FGPGELDSVGSSSDA
Site 20S177ELDSVGSSSDADDHY
Site 21S178LDSVGSSSDADDHYS
Site 22Y184SSDADDHYSLQSGTG
Site 23S185SDADDHYSLQSGTGG
Site 24S188DDHYSLQSGTGGDSG
Site 25S194QSGTGGDSGFGPHCR
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation