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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF268
Full Name:
Zinc finger protein 268
Alias:
Zinc finger protein HZF3
Type:
Mass (Da):
108374
Number AA:
947
UniProt ID:
Q14587
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S20
P
P
L
Q
E
R
N
S
S
W
D
R
I
R
K
Site 2
S21
P
L
Q
E
R
N
S
S
W
D
R
I
R
K
L
Site 3
S33
R
K
L
Q
G
Q
E
S
I
L
G
Q
G
T
P
Site 4
T39
E
S
I
L
G
Q
G
T
P
G
L
Q
P
L
P
Site 5
T48
G
L
Q
P
L
P
G
T
P
R
Q
K
Q
K
S
Site 6
S55
T
P
R
Q
K
Q
K
S
R
R
I
E
K
V
L
Site 7
T75
S
Q
E
Q
P
K
I
T
K
S
W
G
P
L
S
Site 8
S77
E
Q
P
K
I
T
K
S
W
G
P
L
S
F
M
Site 9
Y106
D
P
A
Q
K
C
L
Y
R
S
V
M
L
E
N
Site 10
Y114
R
S
V
M
L
E
N
Y
S
N
L
V
S
L
G
Site 11
S119
E
N
Y
S
N
L
V
S
L
G
Y
Q
H
T
K
Site 12
Y122
S
N
L
V
S
L
G
Y
Q
H
T
K
P
D
I
Site 13
S174
E
N
K
D
K
L
G
S
T
A
K
S
F
E
C
Site 14
S178
K
L
G
S
T
A
K
S
F
E
C
T
T
F
G
Site 15
S191
F
G
K
L
C
L
L
S
T
K
Y
L
S
R
Q
Site 16
T192
G
K
L
C
L
L
S
T
K
Y
L
S
R
Q
K
Site 17
Y194
L
C
L
L
S
T
K
Y
L
S
R
Q
K
P
H
Site 18
S196
L
L
S
T
K
Y
L
S
R
Q
K
P
H
K
C
Site 19
T205
Q
K
P
H
K
C
G
T
H
G
K
S
L
K
Y
Site 20
Y212
T
H
G
K
S
L
K
Y
I
D
F
T
S
D
Y
Site 21
Y219
Y
I
D
F
T
S
D
Y
A
R
N
N
P
N
G
Site 22
Y248
Q
T
V
I
G
I
K
Y
C
E
S
I
E
S
G
Site 23
S251
I
G
I
K
Y
C
E
S
I
E
S
G
K
T
V
Site 24
T257
E
S
I
E
S
G
K
T
V
N
K
K
S
Q
L
Site 25
S289
E
K
A
F
S
S
K
S
Y
L
L
V
H
Q
Q
Site 26
Y290
K
A
F
S
S
K
S
Y
L
L
V
H
Q
Q
T
Site 27
Y304
T
H
A
E
E
K
P
Y
G
C
N
E
C
G
K
Site 28
S314
N
E
C
G
K
D
F
S
S
K
S
Y
L
I
V
Site 29
S315
E
C
G
K
D
F
S
S
K
S
Y
L
I
V
H
Site 30
S317
G
K
D
F
S
S
K
S
Y
L
I
V
H
Q
R
Site 31
Y318
K
D
F
S
S
K
S
Y
L
I
V
H
Q
R
I
Site 32
T327
I
V
H
Q
R
I
H
T
G
E
K
L
H
E
C
Site 33
S335
G
E
K
L
H
E
C
S
E
C
R
K
T
F
S
Site 34
T340
E
C
S
E
C
R
K
T
F
S
F
H
S
Q
L
Site 35
S342
S
E
C
R
K
T
F
S
F
H
S
Q
L
V
I
Site 36
S345
R
K
T
F
S
F
H
S
Q
L
V
I
H
Q
R
Site 37
T355
V
I
H
Q
R
I
H
T
G
E
N
P
Y
E
C
Site 38
Y360
I
H
T
G
E
N
P
Y
E
C
C
E
C
G
K
Site 39
S377
S
R
K
D
Q
L
V
S
H
Q
K
T
H
S
G
Site 40
T381
Q
L
V
S
H
Q
K
T
H
S
G
Q
K
P
Y
Site 41
S383
V
S
H
Q
K
T
H
S
G
Q
K
P
Y
V
C
Site 42
Y388
T
H
S
G
Q
K
P
Y
V
C
N
E
C
G
K
Site 43
S401
G
K
A
F
G
L
K
S
Q
L
I
I
H
E
R
Site 44
T411
I
I
H
E
R
I
H
T
G
E
K
P
Y
E
C
Site 45
Y416
I
H
T
G
E
K
P
Y
E
C
N
E
C
Q
K
Site 46
T437
N
L
M
V
H
Q
R
T
H
T
G
E
K
P
Y
Site 47
T439
M
V
H
Q
R
T
H
T
G
E
K
P
Y
V
C
Site 48
Y444
T
H
T
G
E
K
P
Y
V
C
S
D
C
G
K
Site 49
S447
G
E
K
P
Y
V
C
S
D
C
G
K
A
F
T
Site 50
S457
G
K
A
F
T
F
K
S
Q
L
I
V
H
Q
G
Site 51
Y472
I
H
T
G
V
K
P
Y
G
C
I
Q
C
G
K
Site 52
S485
G
K
G
F
S
L
K
S
Q
L
I
V
H
Q
R
Site 53
T495
I
V
H
Q
R
S
H
T
G
M
K
P
Y
V
C
Site 54
Y500
S
H
T
G
M
K
P
Y
V
C
N
E
C
G
K
Site 55
S511
E
C
G
K
A
F
R
S
K
S
Y
L
I
I
H
Site 56
S513
G
K
A
F
R
S
K
S
Y
L
I
I
H
T
R
Site 57
T521
Y
L
I
I
H
T
R
T
H
T
G
E
K
L
H
Site 58
T523
I
I
H
T
R
T
H
T
G
E
K
L
H
E
C
Site 59
S541
G
K
A
F
S
F
K
S
Q
L
I
I
H
Q
R
Site 60
T551
I
I
H
Q
R
I
H
T
G
E
N
P
Y
E
C
Site 61
Y556
I
H
T
G
E
N
P
Y
E
C
H
E
C
G
K
Site 62
S566
H
E
C
G
K
A
F
S
R
K
Y
Q
L
I
S
Site 63
Y569
G
K
A
F
S
R
K
Y
Q
L
I
S
H
Q
R
Site 64
S573
S
R
K
Y
Q
L
I
S
H
Q
R
T
H
A
G
Site 65
T577
Q
L
I
S
H
Q
R
T
H
A
G
E
K
P
Y
Site 66
Y584
T
H
A
G
E
K
P
Y
E
C
T
D
C
G
K
Site 67
S597
G
K
A
F
G
L
K
S
Q
L
I
I
H
Q
R
Site 68
T605
Q
L
I
I
H
Q
R
T
H
T
G
E
K
P
F
Site 69
T607
I
I
H
Q
R
T
H
T
G
E
K
P
F
E
C
Site 70
S625
Q
K
A
F
N
T
K
S
N
L
I
V
H
Q
R
Site 71
T633
N
L
I
V
H
Q
R
T
H
T
G
E
K
P
Y
Site 72
T635
I
V
H
Q
R
T
H
T
G
E
K
P
Y
S
C
Site 73
Y640
T
H
T
G
E
K
P
Y
S
C
N
E
C
G
K
Site 74
S641
H
T
G
E
K
P
Y
S
C
N
E
C
G
K
A
Site 75
S653
G
K
A
F
T
F
K
S
Q
L
I
V
H
K
G
Site 76
S671
G
V
K
P
Y
G
C
S
Q
C
A
K
T
F
S
Site 77
T676
G
C
S
Q
C
A
K
T
F
S
L
K
S
Q
L
Site 78
S681
A
K
T
F
S
L
K
S
Q
L
I
V
H
Q
R
Site 79
T691
I
V
H
Q
R
S
H
T
G
V
K
P
Y
G
C
Site 80
Y696
S
H
T
G
V
K
P
Y
G
C
S
E
C
G
K
Site 81
S699
G
V
K
P
Y
G
C
S
E
C
G
K
A
F
R
Site 82
S709
G
K
A
F
R
S
K
S
Y
L
I
I
H
M
R
Site 83
T717
Y
L
I
I
H
M
R
T
H
T
G
E
K
P
H
Site 84
T719
I
I
H
M
R
T
H
T
G
E
K
P
H
E
C
Site 85
S732
E
C
R
E
C
G
K
S
F
S
F
N
S
Q
L
Site 86
S734
R
E
C
G
K
S
F
S
F
N
S
Q
L
I
V
Site 87
S737
G
K
S
F
S
F
N
S
Q
L
I
V
H
Q
R
Site 88
T747
I
V
H
Q
R
I
H
T
G
E
N
P
Y
E
C
Site 89
Y752
I
H
T
G
E
N
P
Y
E
C
S
E
C
G
K
Site 90
S769
N
R
K
D
Q
L
I
S
H
Q
R
T
H
A
G
Site 91
Y780
T
H
A
G
E
K
P
Y
G
C
S
E
C
G
K
Site 92
S783
G
E
K
P
Y
G
C
S
E
C
G
K
A
F
S
Site 93
S790
S
E
C
G
K
A
F
S
S
K
S
Y
L
I
I
Site 94
S793
G
K
A
F
S
S
K
S
Y
L
I
I
H
M
R
Site 95
Y794
K
A
F
S
S
K
S
Y
L
I
I
H
M
R
T
Site 96
Y808
T
H
S
G
E
K
P
Y
E
C
N
E
C
G
K
Site 97
S839
G
V
N
P
Y
K
C
S
Q
C
E
K
S
F
S
Site 98
S844
K
C
S
Q
C
E
K
S
F
S
G
K
L
R
L
Site 99
S846
S
Q
C
E
K
S
F
S
G
K
L
R
L
L
V
Site 100
T859
L
V
H
Q
R
M
H
T
R
E
K
P
Y
E
C
Site 101
Y864
M
H
T
R
E
K
P
Y
E
C
S
E
C
G
K
Site 102
S877
G
K
A
F
I
R
N
S
Q
L
I
V
H
Q
R
Site 103
S887
I
V
H
Q
R
T
H
S
G
E
K
P
Y
G
C
Site 104
Y892
T
H
S
G
E
K
P
Y
G
C
N
E
C
G
K
Site 105
T900
G
C
N
E
C
G
K
T
F
S
Q
K
S
I
L
Site 106
S902
N
E
C
G
K
T
F
S
Q
K
S
I
L
S
A
Site 107
S905
G
K
T
F
S
Q
K
S
I
L
S
A
H
Q
R
Site 108
S908
F
S
Q
K
S
I
L
S
A
H
Q
R
T
H
T
Site 109
T913
I
L
S
A
H
Q
R
T
H
T
G
E
K
P
C
Site 110
T915
S
A
H
Q
R
T
H
T
G
E
K
P
C
K
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation