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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF235
Full Name:
Zinc finger protein 235
Alias:
Zinc finger protein 270;Zinc finger protein 93 homolog;Zinc finger protein HZF6
Type:
Mass (Da):
83977
Number AA:
738
UniProt ID:
Q14590
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S27
E
E
L
G
L
L
D
S
A
Q
R
K
L
Y
R
Site 2
Y33
D
S
A
Q
R
K
L
Y
R
D
V
M
L
E
N
Site 3
S46
E
N
F
R
N
L
V
S
V
G
H
Q
S
F
K
Site 4
S51
L
V
S
V
G
H
Q
S
F
K
P
D
M
I
S
Site 5
S58
S
F
K
P
D
M
I
S
Q
L
E
R
E
E
K
Site 6
T73
L
W
M
K
E
L
Q
T
Q
R
G
K
H
S
G
Site 7
S104
C
F
S
L
G
E
L
S
C
W
Q
I
K
R
H
Site 8
S114
Q
I
K
R
H
I
A
S
K
L
A
R
S
Q
D
Site 9
S119
I
A
S
K
L
A
R
S
Q
D
S
M
I
N
I
Site 10
S131
I
N
I
E
G
K
S
S
Q
F
P
K
H
H
D
Site 11
S139
Q
F
P
K
H
H
D
S
P
C
Q
V
G
A
G
Site 12
S182
P
T
G
K
V
P
N
S
W
S
K
I
Y
L
N
Site 13
S184
G
K
V
P
N
S
W
S
K
I
Y
L
N
E
T
Site 14
Y187
P
N
S
W
S
K
I
Y
L
N
E
T
Q
N
Y
Site 15
T191
S
K
I
Y
L
N
E
T
Q
N
Y
Q
R
S
C
Site 16
Y194
Y
L
N
E
T
Q
N
Y
Q
R
S
C
K
Q
T
Site 17
T201
Y
Q
R
S
C
K
Q
T
Q
M
K
N
K
L
C
Site 18
S237
H
K
R
D
K
V
H
S
N
S
D
C
G
K
D
Site 19
S239
R
D
K
V
H
S
N
S
D
C
G
K
D
T
L
Site 20
T245
N
S
D
C
G
K
D
T
L
K
V
S
P
L
T
Site 21
S249
G
K
D
T
L
K
V
S
P
L
T
Q
R
S
I
Site 22
T252
T
L
K
V
S
P
L
T
Q
R
S
I
H
T
G
Site 23
S255
V
S
P
L
T
Q
R
S
I
H
T
G
Q
K
T
Site 24
S275
C
E
E
A
F
N
D
S
S
S
L
E
L
H
K
Site 25
S277
E
A
F
N
D
S
S
S
L
E
L
H
K
Q
V
Site 26
S290
Q
V
H
L
G
K
K
S
P
A
C
S
T
H
E
Site 27
S294
G
K
K
S
P
A
C
S
T
H
E
K
D
T
S
Site 28
T295
K
K
S
P
A
C
S
T
H
E
K
D
T
S
Y
Site 29
T300
C
S
T
H
E
K
D
T
S
Y
S
S
G
I
P
Site 30
S301
S
T
H
E
K
D
T
S
Y
S
S
G
I
P
V
Site 31
Y302
T
H
E
K
D
T
S
Y
S
S
G
I
P
V
Q
Site 32
S311
S
G
I
P
V
Q
Q
S
V
R
T
G
K
K
R
Site 33
Y319
V
R
T
G
K
K
R
Y
W
C
H
E
C
G
K
Site 34
S329
H
E
C
G
K
G
F
S
Q
S
S
N
L
Q
T
Site 35
S331
C
G
K
G
F
S
Q
S
S
N
L
Q
T
H
Q
Site 36
T336
S
Q
S
S
N
L
Q
T
H
Q
R
V
H
T
G
Site 37
T342
Q
T
H
Q
R
V
H
T
G
E
K
P
Y
T
C
Site 38
Y347
V
H
T
G
E
K
P
Y
T
C
H
E
C
G
K
Site 39
S359
C
G
K
S
F
N
Q
S
S
H
L
Y
A
H
L
Site 40
S360
G
K
S
F
N
Q
S
S
H
L
Y
A
H
L
P
Site 41
Y363
F
N
Q
S
S
H
L
Y
A
H
L
P
I
H
T
Site 42
T370
Y
A
H
L
P
I
H
T
G
E
K
P
Y
R
C
Site 43
Y375
I
H
T
G
E
K
P
Y
R
C
D
S
C
G
K
Site 44
S379
E
K
P
Y
R
C
D
S
C
G
K
G
F
S
R
Site 45
S385
D
S
C
G
K
G
F
S
R
S
T
D
L
N
I
Site 46
T388
G
K
G
F
S
R
S
T
D
L
N
I
H
C
R
Site 47
T398
N
I
H
C
R
V
H
T
G
E
K
P
Y
K
C
Site 48
T413
E
V
C
G
K
G
F
T
Q
R
S
H
L
Q
A
Site 49
S416
G
K
G
F
T
Q
R
S
H
L
Q
A
H
E
R
Site 50
T426
Q
A
H
E
R
I
H
T
G
E
K
P
Y
K
C
Site 51
S441
G
D
C
G
K
R
F
S
C
S
S
N
L
H
T
Site 52
S444
G
K
R
F
S
C
S
S
N
L
H
T
H
Q
R
Site 53
T448
S
C
S
S
N
L
H
T
H
Q
R
V
H
T
E
Site 54
T454
H
T
H
Q
R
V
H
T
E
E
K
P
Y
K
C
Site 55
Y459
V
H
T
E
E
K
P
Y
K
C
D
E
C
G
K
Site 56
S469
D
E
C
G
K
C
F
S
L
S
F
N
L
H
S
Site 57
S476
S
L
S
F
N
L
H
S
H
Q
R
V
H
T
G
Site 58
T482
H
S
H
Q
R
V
H
T
G
E
K
P
Y
K
C
Site 59
S497
E
E
C
G
K
G
F
S
S
A
S
S
F
Q
S
Site 60
S498
E
C
G
K
G
F
S
S
A
S
S
F
Q
S
H
Site 61
S500
G
K
G
F
S
S
A
S
S
F
Q
S
H
Q
R
Site 62
S501
K
G
F
S
S
A
S
S
F
Q
S
H
Q
R
V
Site 63
S504
S
S
A
S
S
F
Q
S
H
Q
R
V
H
T
G
Site 64
T510
Q
S
H
Q
R
V
H
T
G
E
K
P
F
R
C
Site 65
S525
N
V
C
G
K
G
F
S
Q
S
S
Y
F
Q
A
Site 66
S528
G
K
G
F
S
Q
S
S
Y
F
Q
A
H
Q
R
Site 67
Y529
K
G
F
S
Q
S
S
Y
F
Q
A
H
Q
R
V
Site 68
T538
Q
A
H
Q
R
V
H
T
G
E
K
P
Y
K
C
Site 69
T566
H
N
H
Q
R
V
H
T
G
E
K
P
Y
K
C
Site 70
S581
E
E
C
G
K
G
F
S
Q
A
S
N
L
Q
A
Site 71
S584
G
K
G
F
S
Q
A
S
N
L
Q
A
H
Q
S
Site 72
S591
S
N
L
Q
A
H
Q
S
V
H
T
G
E
K
P
Site 73
T594
Q
A
H
Q
S
V
H
T
G
E
K
P
F
K
C
Site 74
S609
D
A
C
Q
K
R
F
S
Q
A
S
H
L
Q
A
Site 75
S612
Q
K
R
F
S
Q
A
S
H
L
Q
A
H
Q
R
Site 76
Y627
V
H
T
G
E
K
P
Y
K
C
D
T
C
G
K
Site 77
S637
D
T
C
G
K
A
F
S
Q
R
S
N
L
Q
V
Site 78
T650
Q
V
H
Q
I
I
H
T
G
E
K
P
F
K
C
Site 79
S665
E
E
C
G
K
E
F
S
W
S
A
G
L
S
A
Site 80
S667
C
G
K
E
F
S
W
S
A
G
L
S
A
H
Q
Site 81
S671
F
S
W
S
A
G
L
S
A
H
Q
R
V
H
T
Site 82
T678
S
A
H
Q
R
V
H
T
G
E
K
P
Y
T
C
Site 83
Y683
V
H
T
G
E
K
P
Y
T
C
Q
Q
C
G
K
Site 84
S696
G
K
G
F
S
Q
A
S
H
F
H
T
H
Q
R
Site 85
T700
S
Q
A
S
H
F
H
T
H
Q
R
V
H
T
G
Site 86
T706
H
T
H
Q
R
V
H
T
G
E
R
P
Y
I
C
Site 87
Y711
V
H
T
G
E
R
P
Y
I
C
D
V
C
C
K
Site 88
Y728
S
Q
R
S
H
L
I
Y
H
Q
R
V
H
T
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation