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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Kir6.2
Full Name:
ATP-sensitive inward rectifier potassium channel 11
Alias:
BIR; IKATP; Inward rectifier K channel Kir6.2; Inward rectifier K(+) channel Kir6.2; IRK11; KCNJ11; Potassium channel, inwardly rectifying subfamily J member 11; Potassium channel, inwardly rectifying, subfamily J, member 11; Potassium inwardly-rectifying channel, subfamily J, member 11
Type:
Channel, potassium
Mass (Da):
43541
Number AA:
390
UniProt ID:
Q14654
International Prot ID:
IPI00291902
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0008282
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0015272
GO:0030955
PhosphoSite+
KinaseNET
Biological Process:
GO:0006006
GO:0046676
GO:0050877
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y12
K
G
I
I
P
E
E
Y
V
L
T
R
L
A
E
Site 2
T15
I
P
E
E
Y
V
L
T
R
L
A
E
D
P
A
Site 3
Y26
E
D
P
A
E
P
R
Y
R
A
R
Q
R
R
A
Site 4
S37
Q
R
R
A
R
F
V
S
K
K
G
N
C
N
V
Site 5
T112
G
T
A
E
P
C
V
T
S
I
H
S
F
S
S
Site 6
T180
Q
A
H
R
R
A
E
T
L
I
F
S
K
H
A
Site 7
T223
H
M
Q
V
V
R
K
T
T
S
P
E
G
E
V
Site 8
T224
M
Q
V
V
R
K
T
T
S
P
E
G
E
V
V
Site 9
S225
Q
V
V
R
K
T
T
S
P
E
G
E
V
V
P
Site 10
S265
Y
H
V
I
D
A
N
S
P
L
Y
D
L
A
P
Site 11
Y268
I
D
A
N
S
P
L
Y
D
L
A
P
S
D
L
Site 12
S303
I
T
T
Q
A
R
T
S
Y
L
A
D
E
I
L
Site 13
Y304
T
T
Q
A
R
T
S
Y
L
A
D
E
I
L
W
Site 14
Y326
V
A
E
E
D
G
R
Y
S
V
D
Y
S
K
F
Site 15
S327
A
E
E
D
G
R
Y
S
V
D
Y
S
K
F
G
Site 16
Y330
D
G
R
Y
S
V
D
Y
S
K
F
G
N
T
I
Site 17
S331
G
R
Y
S
V
D
Y
S
K
F
G
N
T
I
K
Site 18
T341
G
N
T
I
K
V
P
T
P
L
C
T
A
R
Q
Site 19
S354
R
Q
L
D
E
D
H
S
L
L
E
A
L
T
L
Site 20
S363
L
E
A
L
T
L
A
S
A
R
G
P
L
R
K
Site 21
S372
R
G
P
L
R
K
R
S
V
P
M
A
K
A
K
Site 22
S383
A
K
A
K
P
K
F
S
I
S
P
D
S
L
S
Site 23
S385
A
K
P
K
F
S
I
S
P
D
S
L
S
_
_
Site 24
S388
K
F
S
I
S
P
D
S
L
S
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation