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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RRP1B
Full Name:
Ribosomal RNA processing protein 1 homolog B
Alias:
KIAA0179; RRP1-like protein B
Type:
Mass (Da):
84411
Number AA:
758
UniProt ID:
Q14684
International Prot ID:
IPI00290952
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005730
GO:0030688
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005515
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006364
GO:0006364
GO:0006396
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
Q
F
A
Q
R
L
A
S
S
E
K
G
I
R
D
Site 2
Y34
A
V
K
K
L
R
Q
Y
I
S
V
K
T
Q
R
Site 3
S36
K
K
L
R
Q
Y
I
S
V
K
T
Q
R
E
T
Site 4
T39
R
Q
Y
I
S
V
K
T
Q
R
E
T
G
G
F
Site 5
T43
S
V
K
T
Q
R
E
T
G
G
F
S
Q
E
E
Site 6
S47
Q
R
E
T
G
G
F
S
Q
E
E
L
L
K
I
Site 7
Y117
D
R
L
R
L
D
K
Y
Y
M
L
I
R
L
V
Site 8
S128
I
R
L
V
L
R
Q
S
F
E
V
L
K
R
N
Site 9
S140
K
R
N
G
W
E
E
S
R
I
K
V
F
L
D
Site 10
S158
K
E
V
L
C
P
E
S
Q
S
P
N
G
V
R
Site 11
S160
V
L
C
P
E
S
Q
S
P
N
G
V
R
F
H
Site 12
S177
D
I
Y
L
D
E
L
S
K
V
G
G
K
E
L
Site 13
T207
A
A
K
T
K
D
H
T
L
V
Q
T
I
A
R
Site 14
S224
F
E
A
I
V
D
Q
S
P
F
V
P
E
E
T
Site 15
T237
E
T
M
E
E
Q
K
T
K
V
G
D
G
D
L
Site 16
S245
K
V
G
D
G
D
L
S
A
E
E
I
P
E
N
Site 17
S255
E
I
P
E
N
E
V
S
L
R
R
A
V
S
K
Site 18
S261
V
S
L
R
R
A
V
S
K
K
K
T
A
L
G
Site 19
T265
R
A
V
S
K
K
K
T
A
L
G
K
N
H
S
Site 20
S272
T
A
L
G
K
N
H
S
R
K
D
G
L
S
D
Site 21
S278
H
S
R
K
D
G
L
S
D
E
R
G
R
D
D
Site 22
T288
R
G
R
D
D
C
G
T
F
E
D
T
G
P
L
Site 23
Y300
G
P
L
L
Q
F
D
Y
K
A
V
A
D
R
L
Site 24
T311
A
D
R
L
L
E
M
T
S
R
K
N
T
P
H
Site 25
S312
D
R
L
L
E
M
T
S
R
K
N
T
P
H
F
Site 26
T316
E
M
T
S
R
K
N
T
P
H
F
N
R
K
R
Site 27
S325
H
F
N
R
K
R
L
S
K
L
I
K
K
F
Q
Site 28
S335
I
K
K
F
Q
D
L
S
E
G
S
S
I
S
Q
Site 29
S338
F
Q
D
L
S
E
G
S
S
I
S
Q
L
S
F
Site 30
S339
Q
D
L
S
E
G
S
S
I
S
Q
L
S
F
A
Site 31
S341
L
S
E
G
S
S
I
S
Q
L
S
F
A
E
D
Site 32
S344
G
S
S
I
S
Q
L
S
F
A
E
D
I
S
A
Site 33
S350
L
S
F
A
E
D
I
S
A
D
E
D
D
Q
I
Site 34
S359
D
E
D
D
Q
I
L
S
Q
G
K
H
K
K
K
Site 35
S392
F
C
V
E
E
E
D
S
E
S
S
L
Q
K
R
Site 36
S394
V
E
E
E
D
S
E
S
S
L
Q
K
R
R
R
Site 37
S395
E
E
E
D
S
E
S
S
L
Q
K
R
R
R
K
Site 38
S422
G
P
G
G
A
A
P
S
L
E
Q
N
R
G
R
Site 39
S434
R
G
R
E
P
E
A
S
G
P
K
A
L
K
A
Site 40
T451
A
E
P
G
A
E
A
T
S
S
T
G
E
E
S
Site 41
S452
T
S
S
T
G
E
E
S
G
S
E
H
P
P
A
Site 42
S453
P
G
A
E
A
T
S
S
T
G
E
E
S
G
S
Site 43
T454
G
A
E
A
T
S
S
T
G
E
E
S
G
S
E
Site 44
S458
T
S
S
T
G
E
E
S
G
S
E
H
P
P
A
Site 45
S460
S
T
G
E
E
S
G
S
E
H
P
P
A
V
P
Site 46
S479
R
K
R
P
R
K
K
S
P
R
A
H
R
E
M
Site 47
S489
A
H
R
E
M
L
E
S
A
V
L
P
P
E
D
Site 48
S498
V
L
P
P
E
D
M
S
Q
S
G
P
S
G
S
Site 49
S500
P
P
E
D
M
S
Q
S
G
P
S
G
S
H
P
Site 50
S505
S
Q
S
G
P
S
G
S
H
P
Q
G
P
R
G
Site 51
S513
H
P
Q
G
P
R
G
S
P
T
G
G
A
Q
L
Site 52
T515
Q
G
P
R
G
S
P
T
G
G
A
Q
L
L
K
Site 53
S538
P
V
N
G
S
G
L
S
T
P
A
W
P
P
L
Site 54
T539
V
N
G
S
G
L
S
T
P
A
W
P
P
L
Q
Site 55
T552
L
Q
Q
E
G
P
P
T
G
P
A
E
G
A
N
Site 56
S560
G
P
A
E
G
A
N
S
H
T
T
L
P
Q
R
Site 57
S579
K
K
K
A
G
P
G
S
L
E
L
C
G
L
P
Site 58
S587
L
E
L
C
G
L
P
S
Q
K
T
A
S
L
K
Site 59
T590
C
G
L
P
S
Q
K
T
A
S
L
K
K
R
K
Site 60
S592
L
P
S
Q
K
T
A
S
L
K
K
R
K
K
M
Site 61
S603
R
K
K
M
R
V
M
S
N
L
V
E
H
N
G
Site 62
S624
G
Q
P
Q
A
L
G
S
S
G
T
C
S
S
L
Site 63
S625
Q
P
Q
A
L
G
S
S
G
T
C
S
S
L
K
Site 64
S629
L
G
S
S
G
T
C
S
S
L
K
K
Q
K
L
Site 65
S630
G
S
S
G
T
C
S
S
L
K
K
Q
K
L
R
Site 66
S640
K
Q
K
L
R
A
E
S
D
F
V
K
F
D
T
Site 67
T647
S
D
F
V
K
F
D
T
P
F
L
P
K
P
L
Site 68
S661
L
F
F
R
R
A
K
S
S
T
A
T
H
P
P
Site 69
S662
F
F
R
R
A
K
S
S
T
A
T
H
P
P
G
Site 70
T663
F
R
R
A
K
S
S
T
A
T
H
P
P
G
P
Site 71
T665
R
A
K
S
S
T
A
T
H
P
P
G
P
A
V
Site 72
T677
P
A
V
Q
L
N
K
T
P
S
S
S
K
K
V
Site 73
S679
V
Q
L
N
K
T
P
S
S
S
K
K
V
T
F
Site 74
S680
Q
L
N
K
T
P
S
S
S
K
K
V
T
F
G
Site 75
S681
L
N
K
T
P
S
S
S
K
K
V
T
F
G
L
Site 76
T685
P
S
S
S
K
K
V
T
F
G
L
N
R
N
M
Site 77
T693
F
G
L
N
R
N
M
T
A
E
F
K
K
T
D
Site 78
T699
M
T
A
E
F
K
K
T
D
K
S
I
L
V
S
Site 79
S702
E
F
K
K
T
D
K
S
I
L
V
S
P
T
G
Site 80
S706
T
D
K
S
I
L
V
S
P
T
G
P
S
R
V
Site 81
T708
K
S
I
L
V
S
P
T
G
P
S
R
V
A
F
Site 82
S711
L
V
S
P
T
G
P
S
R
V
A
F
D
P
E
Site 83
T728
P
L
H
G
V
L
K
T
P
T
S
S
P
A
S
Site 84
T730
H
G
V
L
K
T
P
T
S
S
P
A
S
S
P
Site 85
S731
G
V
L
K
T
P
T
S
S
P
A
S
S
P
L
Site 86
S732
V
L
K
T
P
T
S
S
P
A
S
S
P
L
V
Site 87
S735
T
P
T
S
S
P
A
S
S
P
L
V
A
K
K
Site 88
S736
P
T
S
S
P
A
S
S
P
L
V
A
K
K
P
Site 89
T745
L
V
A
K
K
P
L
T
T
T
P
R
R
R
P
Site 90
T747
A
K
K
P
L
T
T
T
P
R
R
R
P
R
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation