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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LBR
Full Name:
Lamin-B receptor
Alias:
DHCR14B; Integral nuclear envelope inner membrane protein; Lamin B receptor; LMN2R
Type:
DNA binding protein
Mass (Da):
70703
Number AA:
615
UniProt ID:
Q14739
International Prot ID:
IPI00292135
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005639
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0050613
GO:0005521
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
V
R
G
R
W
P
G
S
S
L
Y
Y
E
V
E
Site 2
S20
R
G
R
W
P
G
S
S
L
Y
Y
E
V
E
I
Site 3
Y22
R
W
P
G
S
S
L
Y
Y
E
V
E
I
L
S
Site 4
Y23
W
P
G
S
S
L
Y
Y
E
V
E
I
L
S
H
Site 5
S29
Y
Y
E
V
E
I
L
S
H
D
S
T
S
Q
L
Site 6
S32
V
E
I
L
S
H
D
S
T
S
Q
L
Y
T
V
Site 7
T33
E
I
L
S
H
D
S
T
S
Q
L
Y
T
V
K
Site 8
S34
I
L
S
H
D
S
T
S
Q
L
Y
T
V
K
Y
Site 9
T38
D
S
T
S
Q
L
Y
T
V
K
Y
K
D
G
T
Site 10
Y41
S
Q
L
Y
T
V
K
Y
K
D
G
T
E
L
E
Site 11
T58
E
N
D
I
K
P
L
T
S
F
R
Q
R
K
G
Site 12
S59
N
D
I
K
P
L
T
S
F
R
Q
R
K
G
G
Site 13
S67
F
R
Q
R
K
G
G
S
T
S
S
S
P
S
R
Site 14
T68
R
Q
R
K
G
G
S
T
S
S
S
P
S
R
R
Site 15
S69
Q
R
K
G
G
S
T
S
S
S
P
S
R
R
R
Site 16
S70
R
K
G
G
S
T
S
S
S
P
S
R
R
R
G
Site 17
S71
K
G
G
S
T
S
S
S
P
S
R
R
R
G
S
Site 18
S73
G
S
T
S
S
S
P
S
R
R
R
G
S
R
S
Site 19
S78
S
P
S
R
R
R
G
S
R
S
R
S
R
S
R
Site 20
S80
S
R
R
R
G
S
R
S
R
S
R
S
R
S
P
Site 21
S82
R
R
G
S
R
S
R
S
R
S
R
S
P
G
R
Site 22
S84
G
S
R
S
R
S
R
S
R
S
P
G
R
P
P
Site 23
S86
R
S
R
S
R
S
R
S
P
G
R
P
P
K
S
Site 24
S93
S
P
G
R
P
P
K
S
A
R
R
S
A
S
A
Site 25
S97
P
P
K
S
A
R
R
S
A
S
A
S
H
Q
A
Site 26
S99
K
S
A
R
R
S
A
S
A
S
H
Q
A
D
I
Site 27
S101
A
R
R
S
A
S
A
S
H
Q
A
D
I
K
E
Site 28
T118
R
E
V
E
V
K
L
T
P
L
I
L
K
P
F
Site 29
S128
I
L
K
P
F
G
N
S
I
S
R
Y
N
G
E
Site 30
S130
K
P
F
G
N
S
I
S
R
Y
N
G
E
P
E
Site 31
Y132
F
G
N
S
I
S
R
Y
N
G
E
P
E
H
I
Site 32
S154
K
N
T
Q
E
K
F
S
L
S
Q
E
S
S
Y
Site 33
S156
T
Q
E
K
F
S
L
S
Q
E
S
S
Y
I
A
Site 34
S160
F
S
L
S
Q
E
S
S
Y
I
A
T
Q
Y
S
Site 35
Y161
S
L
S
Q
E
S
S
Y
I
A
T
Q
Y
S
L
Site 36
T164
Q
E
S
S
Y
I
A
T
Q
Y
S
L
R
P
R
Site 37
Y166
S
S
Y
I
A
T
Q
Y
S
L
R
P
R
R
E
Site 38
S167
S
Y
I
A
T
Q
Y
S
L
R
P
R
R
E
E
Site 39
S182
V
K
L
K
E
I
D
S
K
E
E
K
Y
V
A
Site 40
Y187
I
D
S
K
E
E
K
Y
V
A
K
E
L
A
V
Site 41
T196
A
K
E
L
A
V
R
T
F
E
V
T
P
I
R
Site 42
T200
A
V
R
T
F
E
V
T
P
I
R
A
K
D
L
Site 43
S239
M
C
K
Q
K
D
P
S
L
L
N
F
P
P
P
Site 44
Y251
P
P
P
L
P
A
L
Y
E
L
W
E
T
R
V
Site 45
T284
I
G
K
V
V
E
G
T
P
L
I
D
G
R
R
Site 46
Y294
I
D
G
R
R
L
K
Y
R
L
N
G
F
Y
A
Site 47
Y321
F
Q
G
V
E
F
H
Y
V
Y
S
H
F
L
Q
Site 48
S357
K
A
P
R
N
D
L
S
P
A
S
S
G
N
A
Site 49
S360
R
N
D
L
S
P
A
S
S
G
N
A
V
Y
D
Site 50
S361
N
D
L
S
P
A
S
S
G
N
A
V
Y
D
F
Site 51
Y366
A
S
S
G
N
A
V
Y
D
F
F
I
G
R
E
Site 52
T380
E
L
N
P
R
I
G
T
F
D
L
K
Y
F
C
Site 53
Y385
I
G
T
F
D
L
K
Y
F
C
E
L
R
P
G
Site 54
Y474
I
Y
S
F
Q
A
F
Y
L
V
S
H
P
N
E
Site 55
S506
V
I
F
R
G
A
N
S
Q
K
N
A
F
R
K
Site 56
S516
N
A
F
R
K
N
P
S
D
P
K
L
A
H
L
Site 57
T525
P
K
L
A
H
L
K
T
I
H
T
S
T
G
K
Site 58
Y589
H
R
E
A
R
D
E
Y
H
C
K
K
K
Y
G
Site 59
Y595
E
Y
H
C
K
K
K
Y
G
V
A
W
E
K
Y
Site 60
Y602
Y
G
V
A
W
E
K
Y
C
Q
R
V
P
Y
R
Site 61
Y608
K
Y
C
Q
R
V
P
Y
R
I
F
P
Y
I
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation