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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
COG2
Full Name:
Conserved oligomeric Golgi complex subunit 2
Alias:
Component of oligomeric Golgi complex 2;Low density lipoprotein receptor defect C-complementing protein
Type:
Mass (Da):
83208
Number AA:
738
UniProt ID:
Q14746
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
N
L
P
K
G
P
D
T
L
C
F
D
K
D
E
Site 2
Y52
L
R
D
D
L
E
L
Y
Y
K
L
L
K
T
A
Site 3
S89
D
K
A
L
N
Q
L
S
V
P
L
G
Q
L
R
Site 4
S101
Q
L
R
E
E
V
L
S
L
R
S
S
V
S
E
Site 5
S105
E
V
L
S
L
R
S
S
V
S
E
G
I
R
A
Site 6
S107
L
S
L
R
S
S
V
S
E
G
I
R
A
V
D
Site 7
S118
R
A
V
D
E
R
M
S
K
Q
E
D
I
R
K
Site 8
S149
K
I
E
K
I
L
N
S
Q
S
S
K
E
T
S
Site 9
S151
E
K
I
L
N
S
Q
S
S
K
E
T
S
A
L
Site 10
S152
K
I
L
N
S
Q
S
S
K
E
T
S
A
L
E
Site 11
S156
S
Q
S
S
K
E
T
S
A
L
E
A
S
S
P
Site 12
T175
Q
I
L
E
R
I
A
T
E
F
N
Q
L
Q
F
Site 13
S222
L
L
E
G
L
Q
T
S
D
V
D
I
I
R
H
Site 14
T233
I
I
R
H
C
L
R
T
Y
A
T
I
D
K
T
Site 15
Y234
I
R
H
C
L
R
T
Y
A
T
I
D
K
T
R
Site 16
T240
T
Y
A
T
I
D
K
T
R
D
A
E
A
L
V
Site 17
S267
I
I
E
Q
F
V
E
S
H
P
N
G
L
Q
V
Site 18
T294
C
R
L
L
R
E
V
T
G
G
A
I
S
S
E
Site 19
S300
V
T
G
G
A
I
S
S
E
K
G
N
T
V
P
Site 20
T305
I
S
S
E
K
G
N
T
V
P
G
Y
D
F
L
Site 21
Y309
K
G
N
T
V
P
G
Y
D
F
L
V
N
S
V
Site 22
S330
G
L
E
E
K
L
P
S
L
F
N
P
G
N
P
Site 23
Y344
P
D
A
F
H
E
K
Y
T
I
S
M
D
F
V
Site 24
S360
R
L
E
R
Q
C
G
S
Q
A
S
V
K
R
L
Site 25
S363
R
Q
C
G
S
Q
A
S
V
K
R
L
R
A
H
Site 26
Y373
R
L
R
A
H
P
A
Y
H
S
F
N
K
K
W
Site 27
Y385
K
K
W
N
L
P
V
Y
F
Q
I
R
F
R
E
Site 28
S396
R
F
R
E
I
A
G
S
L
E
A
A
L
T
D
Site 29
Y414
D
A
P
A
E
S
P
Y
C
L
L
A
S
H
R
Site 30
S419
S
P
Y
C
L
L
A
S
H
R
T
W
S
S
L
Site 31
S424
L
A
S
H
R
T
W
S
S
L
R
R
C
W
S
Site 32
S425
A
S
H
R
T
W
S
S
L
R
R
C
W
S
D
Site 33
S431
S
S
L
R
R
C
W
S
D
E
M
F
L
P
L
Site 34
S462
S
V
F
V
N
E
L
S
L
R
P
I
S
N
E
Site 35
S467
E
L
S
L
R
P
I
S
N
E
S
P
K
E
I
Site 36
S470
L
R
P
I
S
N
E
S
P
K
E
I
K
K
P
Site 37
T480
E
I
K
K
P
L
V
T
G
S
K
E
P
S
I
Site 38
S482
K
K
P
L
V
T
G
S
K
E
P
S
I
T
Q
Site 39
S486
V
T
G
S
K
E
P
S
I
T
Q
G
N
T
E
Site 40
T488
G
S
K
E
P
S
I
T
Q
G
N
T
E
D
Q
Site 41
S497
G
N
T
E
D
Q
G
S
G
P
S
E
T
K
P
Site 42
T502
Q
G
S
G
P
S
E
T
K
P
V
V
S
I
S
Site 43
S550
F
K
N
F
S
S
I
S
A
A
L
E
D
S
Q
Site 44
S556
I
S
A
A
L
E
D
S
Q
S
S
F
S
A
C
Site 45
S558
A
A
L
E
D
S
Q
S
S
F
S
A
C
V
P
Site 46
S559
A
L
E
D
S
Q
S
S
F
S
A
C
V
P
S
Site 47
S561
E
D
S
Q
S
S
F
S
A
C
V
P
S
L
S
Site 48
Y593
A
L
E
V
P
R
L
Y
R
R
T
N
K
E
V
Site 49
T596
V
P
R
L
Y
R
R
T
N
K
E
V
P
T
T
Site 50
T602
R
T
N
K
E
V
P
T
T
A
S
S
Y
V
D
Site 51
T603
T
N
K
E
V
P
T
T
A
S
S
Y
V
D
S
Site 52
S605
K
E
V
P
T
T
A
S
S
Y
V
D
S
A
L
Site 53
S606
E
V
P
T
T
A
S
S
Y
V
D
S
A
L
K
Site 54
Y607
V
P
T
T
A
S
S
Y
V
D
S
A
L
K
P
Site 55
S610
T
A
S
S
Y
V
D
S
A
L
K
P
L
F
Q
Site 56
S620
K
P
L
F
Q
L
Q
S
G
H
K
D
K
L
K
Site 57
T638
I
Q
Q
W
L
E
G
T
L
S
E
S
T
H
K
Site 58
S640
Q
W
L
E
G
T
L
S
E
S
T
H
K
Y
Y
Site 59
S642
L
E
G
T
L
S
E
S
T
H
K
Y
Y
E
T
Site 60
Y646
L
S
E
S
T
H
K
Y
Y
E
T
V
S
D
V
Site 61
Y647
S
E
S
T
H
K
Y
Y
E
T
V
S
D
V
L
Site 62
T649
S
T
H
K
Y
Y
E
T
V
S
D
V
L
N
S
Site 63
S651
H
K
Y
Y
E
T
V
S
D
V
L
N
S
V
K
Site 64
S663
S
V
K
K
M
E
E
S
L
K
R
L
K
Q
A
Site 65
T673
R
L
K
Q
A
R
K
T
T
P
A
N
P
V
G
Site 66
T674
L
K
Q
A
R
K
T
T
P
A
N
P
V
G
P
Site 67
S682
P
A
N
P
V
G
P
S
G
G
M
S
D
D
D
Site 68
S686
V
G
P
S
G
G
M
S
D
D
D
K
I
R
L
Site 69
Y701
Q
L
A
L
D
V
E
Y
L
G
E
Q
I
Q
K
Site 70
S714
Q
K
L
G
L
Q
A
S
D
I
K
S
F
S
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation