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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GNMT
Full Name:
Glycine N-methyltransferase
Alias:
Type:
Mass (Da):
32742
Number AA:
295
UniProt ID:
Q14749
International Prot ID:
IPI00215925
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005542
GO:0017174
GO:0016594
PhosphoSite+
KinaseNET
Biological Process:
GO:0046500
GO:0006555
GO:0051289
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
D
S
V
Y
R
T
R
S
L
G
V
A
A
E
G
Site 2
Y22
A
E
G
L
P
D
Q
Y
A
D
G
E
A
A
R
Site 3
Y34
A
A
R
V
W
Q
L
Y
I
G
D
T
R
S
R
Site 4
T38
W
Q
L
Y
I
G
D
T
R
S
R
T
A
E
Y
Site 5
S40
L
Y
I
G
D
T
R
S
R
T
A
E
Y
K
A
Site 6
T42
I
G
D
T
R
S
R
T
A
E
Y
K
A
W
L
Site 7
S72
A
C
G
T
G
V
D
S
I
M
L
V
E
E
G
Site 8
S84
E
E
G
F
S
V
T
S
V
D
A
S
D
K
M
Site 9
S88
S
V
T
S
V
D
A
S
D
K
M
L
K
Y
A
Site 10
Y94
A
S
D
K
M
L
K
Y
A
L
K
E
R
W
N
Site 11
S142
A
V
I
C
L
G
N
S
F
A
H
L
P
D
C
Site 12
S154
P
D
C
K
G
D
Q
S
E
H
R
L
A
L
K
Site 13
Y180
L
V
I
D
H
R
N
Y
D
H
I
L
S
T
G
Site 14
S185
R
N
Y
D
H
I
L
S
T
G
C
A
P
P
G
Site 15
T186
N
Y
D
H
I
L
S
T
G
C
A
P
P
G
K
Site 16
Y196
A
P
P
G
K
N
I
Y
Y
K
S
D
L
T
K
Site 17
Y197
P
P
G
K
N
I
Y
Y
K
S
D
L
T
K
D
Site 18
S199
G
K
N
I
Y
Y
K
S
D
L
T
K
D
V
T
Site 19
T202
I
Y
Y
K
S
D
L
T
K
D
V
T
T
S
V
Site 20
T220
N
N
K
A
H
M
V
T
L
D
Y
T
V
Q
V
Site 21
Y223
A
H
M
V
T
L
D
Y
T
V
Q
V
P
G
A
Site 22
T224
H
M
V
T
L
D
Y
T
V
Q
V
P
G
A
G
Site 23
S235
P
G
A
G
Q
D
G
S
P
G
L
S
K
F
R
Site 24
S239
Q
D
G
S
P
G
L
S
K
F
R
L
S
Y
Y
Site 25
S244
G
L
S
K
F
R
L
S
Y
Y
P
H
C
L
A
Site 26
Y245
L
S
K
F
R
L
S
Y
Y
P
H
C
L
A
S
Site 27
Y246
S
K
F
R
L
S
Y
Y
P
H
C
L
A
S
F
Site 28
S252
Y
Y
P
H
C
L
A
S
F
T
E
L
L
Q
A
Site 29
T254
P
H
C
L
A
S
F
T
E
L
L
Q
A
A
F
Site 30
S268
F
G
G
K
C
Q
H
S
V
L
G
D
F
K
P
Site 31
Y276
V
L
G
D
F
K
P
Y
K
P
G
Q
T
Y
I
Site 32
Y282
P
Y
K
P
G
Q
T
Y
I
P
C
Y
F
I
H
Site 33
Y286
G
Q
T
Y
I
P
C
Y
F
I
H
V
L
K
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation