PhosphoNET

           
Protein Info 
   
Short Name:  HLX1
Full Name:  H2.0-like homeobox protein
Alias:  Homeobox protein HB24;Homeobox protein HLX1
Type:  Transcription protein
Mass (Da):  50789
Number AA:  488
UniProt ID:  Q14774
International Prot ID:  IPI00292164
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0043565  GO:0003700   PhosphoSite+ KinaseNET
Biological Process:  GO:0030154  GO:0006355  GO:0006350 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S24WSAAYCSSAGPGGCS
Site 2S84GSVHPHASFQAAARS
Site 3S91SFQAAARSPLRPTPV
Site 4T96ARSPLRPTPVVAPSE
Site 5S113AGFPQRLSPLSAAYH
Site 6S116PQRLSPLSAAYHHHH
Site 7S152GALQPPASGTRVVPN
Site 8S163VVPNPHHSGSAPAPS
Site 9S165PNPHHSGSAPAPSSK
Site 10S170SGSAPAPSSKDLKFG
Site 11S171GSAPAPSSKDLKFGI
Site 12T195PKVKEGNTLRDLTSL
Site 13T200GNTLRDLTSLLTGGR
Site 14S201NTLRDLTSLLTGGRP
Site 15T204RDLTSLLTGGRPAGV
Site 16S214RPAGVHLSGLQPSAG
Site 17S219HLSGLQPSAGQFFAS
Site 18S226SAGQFFASLDPINEA
Site 19S238NEASAILSPLNSNPR
Site 20S242AILSPLNSNPRNSVQ
Site 21S247LNSNPRNSVQHQFQD
Site 22T255VQHQFQDTFPGPYAV
Site 23T264PGPYAVLTKDTMPQT
Site 24T271TKDTMPQTYKRKRSW
Site 25Y272KDTMPQTYKRKRSWS
Site 26S277QTYKRKRSWSRAVFS
Site 27S279YKRKRSWSRAVFSNL
Site 28Y300KRFEIQKYVTKPDRK
Site 29S334RRMKWRHSKEAQAQK
Site 30S366DGEQDERSPSRSEGE
Site 31S368EQDERSPSRSEGEAE
Site 32S370DERSPSRSEGEAESE
Site 33S376RSEGEAESESSDSES
Site 34S378EGEAESESSDSESLD
Site 35S379GEAESESSDSESLDM
Site 36S381AESESSDSESLDMAP
Site 37S383SESSDSESLDMAPSD
Site 38S389ESLDMAPSDTERTEG
Site 39T391LDMAPSDTERTEGSE
Site 40S397DTERTEGSERSLHQT
Site 41S400RTEGSERSLHQTTVI
Site 42T404SERSLHQTTVIKAPV
Site 43S423ITASSAGSGGSSGGG
Site 44S426SSAGSGGSSGGGGNS
Site 45S427SAGSGGSSGGGGNSF
Site 46S433SSGGGGNSFSFSSAS
Site 47S435GGGGNSFSFSSASSL
Site 48S437GGNSFSFSSASSLSS
Site 49S438GNSFSFSSASSLSSS
Site 50S440SFSFSSASSLSSSST
Site 51S441FSFSSASSLSSSSTS
Site 52S443FSSASSLSSSSTSAG
Site 53S444SSASSLSSSSTSAGC
Site 54S445SASSLSSSSTSAGCA
Site 55S446ASSLSSSSTSAGCAS
Site 56T447SSLSSSSTSAGCASS
Site 57S448SLSSSSTSAGCASSL
Site 58T467ASELLPATQPTASSA
Site 59S472PATQPTASSAPKSPE
Site 60S473ATQPTASSAPKSPEP
Site 61S477TASSAPKSPEPAQGA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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