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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CBX2
Full Name:
Chromobox protein homolog 2
Alias:
Type:
Mass (Da):
56063
Number AA:
532
UniProt ID:
Q14781
International Prot ID:
IPI00651642
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000785
GO:0005634
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003677
GO:0003682
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006325
GO:0006333
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
F
A
A
E
C
I
L
S
K
R
L
R
K
G
K
Site 2
Y29
L
R
K
G
K
L
E
Y
L
V
K
W
R
G
W
Site 3
S42
G
W
S
S
K
H
N
S
W
E
P
E
E
N
I
Site 4
T84
R
G
R
P
R
K
L
T
A
M
S
S
C
S
R
Site 5
S88
R
K
L
T
A
M
S
S
C
S
R
R
S
K
L
Site 6
S90
L
T
A
M
S
S
C
S
R
R
S
K
L
K
E
Site 7
S93
M
S
S
C
S
R
R
S
K
L
K
E
P
D
A
Site 8
S102
L
K
E
P
D
A
P
S
K
S
K
S
S
S
S
Site 9
S104
E
P
D
A
P
S
K
S
K
S
S
S
S
S
S
Site 10
S106
D
A
P
S
K
S
K
S
S
S
S
S
S
S
S
Site 11
S107
A
P
S
K
S
K
S
S
S
S
S
S
S
S
T
Site 12
S108
P
S
K
S
K
S
S
S
S
S
S
S
S
T
S
Site 13
S109
S
K
S
K
S
S
S
S
S
S
S
S
T
S
S
Site 14
S110
K
S
K
S
S
S
S
S
S
S
S
T
S
S
S
Site 15
S111
S
K
S
S
S
S
S
S
S
S
T
S
S
S
S
Site 16
S112
K
S
S
S
S
S
S
S
S
T
S
S
S
S
S
Site 17
S113
S
S
S
S
S
S
S
S
T
S
S
S
S
S
S
Site 18
T114
S
S
S
S
S
S
S
T
S
S
S
S
S
S
D
Site 19
S115
S
S
S
S
S
S
T
S
S
S
S
S
S
D
E
Site 20
S116
S
S
S
S
S
T
S
S
S
S
S
S
D
E
E
Site 21
S117
S
S
S
S
T
S
S
S
S
S
S
D
E
E
D
Site 22
S118
S
S
S
T
S
S
S
S
S
S
D
E
E
D
D
Site 23
S119
S
S
T
S
S
S
S
S
S
D
E
E
D
D
S
Site 24
S120
S
T
S
S
S
S
S
S
D
E
E
D
D
S
D
Site 25
S126
S
S
D
E
E
D
D
S
D
L
D
A
K
R
G
Site 26
T139
R
G
P
R
G
R
E
T
H
P
V
P
Q
K
K
Site 27
T176
L
P
P
E
Q
K
A
T
R
R
P
V
S
L
A
Site 28
S181
K
A
T
R
R
P
V
S
L
A
K
V
L
K
T
Site 29
T188
S
L
A
K
V
L
K
T
A
R
K
D
L
G
A
Site 30
S198
K
D
L
G
A
P
A
S
K
L
P
P
P
L
S
Site 31
S226
K
E
A
C
G
G
P
S
A
M
A
T
P
E
N
Site 32
T230
G
G
P
S
A
M
A
T
P
E
N
L
A
S
L
Site 33
S236
A
T
P
E
N
L
A
S
L
M
K
G
M
A
S
Site 34
S243
S
L
M
K
G
M
A
S
S
P
G
R
G
G
I
Site 35
S244
L
M
K
G
M
A
S
S
P
G
R
G
G
I
S
Site 36
S251
S
P
G
R
G
G
I
S
W
Q
S
S
I
V
H
Site 37
Y259
W
Q
S
S
I
V
H
Y
M
N
R
M
T
Q
S
Site 38
S266
Y
M
N
R
M
T
Q
S
Q
A
Q
A
A
S
R
Site 39
T281
L
A
L
K
A
Q
A
T
N
K
C
G
L
G
L
Site 40
T294
G
L
D
L
K
V
R
T
Q
K
G
E
L
G
M
Site 41
S302
Q
K
G
E
L
G
M
S
P
P
G
S
K
I
P
Site 42
S306
L
G
M
S
P
P
G
S
K
I
P
K
A
P
S
Site 43
T330
N
T
G
G
P
P
H
T
H
G
A
S
R
V
P
Site 44
S334
P
P
H
T
H
G
A
S
R
V
P
A
G
C
P
Site 45
T348
P
G
P
Q
P
A
P
T
Q
E
L
S
L
Q
V
Site 46
S352
P
A
P
T
Q
E
L
S
L
Q
V
L
D
L
Q
Site 47
S360
L
Q
V
L
D
L
Q
S
V
K
N
G
M
P
G
Site 48
S394
A
P
G
K
G
T
G
S
G
L
I
G
A
S
G
Site 49
T406
A
S
G
A
T
M
P
T
D
T
S
K
S
E
K
Site 50
S409
A
T
M
P
T
D
T
S
K
S
E
K
L
A
S
Site 51
S411
M
P
T
D
T
S
K
S
E
K
L
A
S
R
A
Site 52
S416
S
K
S
E
K
L
A
S
R
A
V
A
P
P
T
Site 53
T423
S
R
A
V
A
P
P
T
P
A
S
K
R
D
C
Site 54
S426
V
A
P
P
T
P
A
S
K
R
D
C
V
K
G
Site 55
S434
K
R
D
C
V
K
G
S
A
T
P
S
G
Q
E
Site 56
T436
D
C
V
K
G
S
A
T
P
S
G
Q
E
S
R
Site 57
S438
V
K
G
S
A
T
P
S
G
Q
E
S
R
T
A
Site 58
S442
A
T
P
S
G
Q
E
S
R
T
A
P
G
E
A
Site 59
S459
A
A
T
L
P
E
M
S
A
G
E
E
S
S
S
Site 60
S464
E
M
S
A
G
E
E
S
S
S
S
D
S
D
P
Site 61
S465
M
S
A
G
E
E
S
S
S
S
D
S
D
P
D
Site 62
S466
S
A
G
E
E
S
S
S
S
D
S
D
P
D
S
Site 63
S467
A
G
E
E
S
S
S
S
D
S
D
P
D
S
A
Site 64
S469
E
E
S
S
S
S
D
S
D
P
D
S
A
S
P
Site 65
S473
S
S
D
S
D
P
D
S
A
S
P
P
S
T
G
Site 66
S475
D
S
D
P
D
S
A
S
P
P
S
T
G
Q
N
Site 67
S478
P
D
S
A
S
P
P
S
T
G
Q
N
P
S
V
Site 68
T479
D
S
A
S
P
P
S
T
G
Q
N
P
S
V
S
Site 69
S484
P
S
T
G
Q
N
P
S
V
S
V
Q
T
S
Q
Site 70
S486
T
G
Q
N
P
S
V
S
V
Q
T
S
Q
D
W
Site 71
S490
P
S
V
S
V
Q
T
S
Q
D
W
K
P
T
R
Site 72
S498
Q
D
W
K
P
T
R
S
L
I
E
H
V
F
V
Site 73
T516
T
A
N
L
I
T
V
T
V
K
E
S
P
T
S
Site 74
S523
T
V
K
E
S
P
T
S
V
G
F
F
N
L
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation